Abstract: Methods, apparatus and kits for preparing a medical mixture are disclosed. A method of preparing the medical mixture includes introducing a material into a tray, transferring the material from the tray to a scooper, releasably securing the scooper to the tray, and introducing a tubular member defining a lumen into the scooper such that the material within the scooper enters the lumen. A mixing apparatus includes a tray comprising a body defining a mixing receptacle configured to receive a material, a scooper having a proximal end with a proximal opening and a distal end with a distal opening, and a connector configured to releasably secure the scooper to the tray. A kit includes a tubular member, a stylet, a tray, and a scooper.

Abstract: Methods, apparatus and kits for preparing a medical mixture are disclosed. A method of preparing the medical mixture includes introducing a material into a tray, transferring the material from the tray to a scooper, releasably securing the scooper to the tray, and introducing a tubular member defining a lumen into the scooper such that the material within the scooper enters the lumen. A mixing apparatus includes a tray comprising a body defining a mixing receptacle configured to receive a material, a scooper having a proximal end with a proximal opening and a distal end with a distal opening, and a connector configured to releasably secure the scooper to the tray. A kit includes a tubular member, a stylet, a tray, and a scooper.

Abstract: An applicator and method for dispensing a stream of a particulate and a fluid from a cannula and a mixing tip. The mixing tip includes a housing having an inlet, an outlet, and a mixing channel extending therebetween. A fin is positioned within the housing and extends along at least a portion of the mixing channel. The fin spirals about the mixing channel from the inlet toward the outlet for mixing and distributing the particulate generally uniformly within the fluid. The stream is directed into the mixing channel of the mixing tip and spiraled along the fin within the mixing channel. The spiraling increases turbulence and mixes the stream into a mixed stream of particulate and fluid. The mixed stream is discharged from the mixing tip for being dispensed onto an anatomical site.

Abstract: A dispensing assembly includes a syringe body having a barrel and a dispensing tip. The dispensing assembly further includes a mixing and plunging assembly configured for coupling with the syringe body and comprising a mixer and a plunger. The mixer is configured for mixing material in the barrel and has a rod and a mixing element removably connected with the rod. The plunger is configured to dispense material from the barrel through the dispensing tip. Also, the rod is configured to be detached from the mixing element and used to push material out of the dispensing tip.

Abstract: A device and method for removing gas from a mixture of biomaterials includes a vacuum pump movably positioned within a cavity of a syringe at least partially defining a vacuum chamber. The vacuum pump has a pump body with proximal and distal portions, a stopper connected to the distal portion, and a flow channel. The stopper includes an inlet, and the pump body includes a port. The flow channel extends from the inlet to the port and is in fluid communication with the vacuum chamber. A first valve is positioned within the flow channel between the inlet and the port. The first valve is operable to open and close the flow channel for selectively connecting a vacuum to the vacuum chamber such that gas is withdrawn from mixture of biomaterials within the vacuum chamber.

Abstract: A device and method for removing gas from a mixture of biomaterials includes a vacuum pump movably positioned within a cavity of a syringe at least partially defining a vacuum chamber. The vacuum pump has a pump body with proximal and distal portions, a stopper connected to the distal portion, and a flow channel. The stopper includes an inlet, and the pump body includes a port. The flow channel extends from the inlet to the port and is in fluid communication with the vacuum chamber. A first valve is positioned within the flow channel between the inlet and the port. The first valve is operable to open and close the flow channel for selectively connecting a vacuum to the vacuum chamber such that gas is withdrawn from mixture of biomaterials within the vacuum chamber.

Abstract: A device and method for removing gas from a mixture of biomaterials includes a vacuum pump movably positioned within a cavity of a syringe at least partially defining a vacuum chamber. The vacuum pump has a pump body with proximal and distal portions, a stopper connected to the distal portion, and a flow channel. The stopper includes an inlet, and the pump body includes a port. The flow channel extends from the inlet to the port and is in fluid communication with the vacuum chamber. A first valve is positioned within the flow channel between the inlet and the port. The first valve is operable to open and close the flow channel for selectively connecting a vacuum to the vacuum chamber such that gas is withdrawn from mixture of biomaterials within the vacuum chamber.

Abstract: An instrument for delivery, deployment, and tamponade of a hemostat. A delivery cannula is included and has a proximal end, a distal end, and a lumen therebetween. A shaft is configured to be introduced into and move relative to the lumen. A hemostat applicator at the distal end of the shaft includes a tamponade surface. The applicator is configured to transition between a first, compact state for introduction into and movement within the lumen, and a second, expanded state as the applicator exits from the delivery cannula.

Abstract: A dispensing assembly includes a syringe body having a barrel and a dispensing tip. The dispensing assembly further includes a mixing and plunging assembly configured for coupling with the syringe body and comprising a mixer and a plunger. The mixer is configured for mixing material in the barrel and has a rod and a mixing element removably connected with the rod. The plunger is configured to dispense material from the barrel through the dispensing tip. Also, the rod is configured to be detached from the mixing element and used to push material out of the dispensing tip.

Abstract: A regulator for regulating the pressure and flow of gas traveling between a gas inlet and a gas outlet. A first pressure regulator in fluid communication with the gas inlet and configured to prevent gas flowing downstream of the first pressure regulator from exceeding a first pressure. A first line between the first pressure regulator and the gas outlet. A second pressure reducing device in fluid communication with the first line downstream of the first pressure regulator and configured to prevent gas flowing in the first line at a point downstream of the second pressure regulator from exceeding a second pressure. A control valve actuatable to an open position when gas is transmitted to a first pilot valve at or below the second pressure, the first pilot valve in fluid communication with the first line.

Abstract: A device and method for removing gas from a mixture of biomaterials includes a vacuum pump movably positioned within a cavity of a syringe at least partially defining a vacuum chamber. The vacuum pump has a pump body with proximal and distal portions, a stopper connected to the distal portion, and a flow channel. The stopper includes an inlet, and the pump body includes a port. The flow channel extends from the inlet to the port and is in fluid communication with the vacuum chamber. A first valve is positioned within the flow channel between the inlet and the port. The first valve is operable to open and close the flow channel for selectively connecting a vacuum to the vacuum chamber such that gas is withdrawn from mixture of biomaterials within the vacuum chamber.

Abstract: An applicator and method for dispensing a stream of a particulate and a fluid from a cannula and a mixing tip. The mixing tip includes a housing having an inlet, an outlet, and a mixing channel extending therebetween. A fin is positioned within the housing and extends along at least a portion of the mixing channel. The fin spirals about the mixing channel from the inlet toward the outlet for mixing and distributing the particulate generally uniformly within the fluid. The stream is directed into the mixing channel of the mixing tip and spiraled along the fin within the mixing channel. The spiraling increases turbulence and mixes the stream into a mixed stream of particulate and fluid. The mixed stream is discharged from the mixing tip for being dispensed onto an anatomical site.

Abstract: A device and method for dispensing a liquid and a gas from a tip includes a support structure, a control unit, and a drive unit. The liquid is held within a container. The support structure is adapted to hold the container. The control unit directs the drive unit to expel liquid from the container according to a predetermined rate. The control unit further directs the drive unit according to first, second, and third modes of operation. During the first mode, neither gas nor liquid is dispensed from the device. During the second mode, only gas is dispensed from the device. During the third mode, both gas and liquid are dispensed from the device. Furthermore, the control unit is only selectable and operable by a user through the first, second, and third modes in a sequential manner.

Abstract: A gas-assisted fluid-dispensing device configured to deliver an aerosol onto a surgical site. The fluid-dispensing device includes at least one fluid chamber configured to contain a fluid. The fluid chamber has a distal end and proximal end. A plunger extends at least partially into the fluid chamber from the proximal end. A spray nozzle tip is fluidly coupled to the distal end of the fluid chamber and is coupled to a gas supply. The tip is capable of generating aerosol with a gas from the gas supply and the fluid from the fluid chamber. A housing has an upper portion with a docking port configured to operably receive the fluid chamber. An actuating member is operably coupled to a plunger and is configured to apply a force to the plunger to discharge fluid from the fluid chamber and into the tip.

Abstract: A gas-assisted fluid-dispensing device (10) for delivering an aerosol. The gas-assisted fluid-dispensing device (10) includes a syringe (14) that contains a fluid and includes a distal end (18), a proximal end (20), and a plunger (24) extending proximally from the proximal end (20). A spray nozzle tip (26) is configured to generate the aerosol and is coupled to the distal end (18) of the syringe (14). The gas-assisted fluid-dispensing device (10) further includes a housing (44) having first and second housing portions (52, 54). The first housing portion (52) includes a docking port (42) for receiving the syringe (14); the second housing portion (54) is configured as a handle. A trigger (50), coupled to the housing (44), is operably coupled to an actuating member (58) that is configured to apply a force onto the plunger (24) of the syringe (14) and discharge the fluid from the syringe (14) and into the spray nozzle tip (26).

Abstract: A spray nozzle for applying a medicinal agent to a tissue. The spray nozzle comprising a tip housing and a valve. The tip housing has a distal end, a proximal end, and a lumen that extends between the ends and defines a lengthwise central axis. The valve has an elongated body that extends through the lumen of the tip housing, along the lengthwise central axis. The valve, being configured to slide within the lumen of the tip housing, in an extended position with respect therewith is configured to disperse the medicinal agent toward the tissue. When the valve is in the retracted position with respect to the tip housing, the medicinal agent is vented away from the tissue.

Abstract: A gas-assisted fluid-dispensing device (10) for delivering an aerosol. The gas-assisted fluid-dispensing device (10) includes a syringe (14) that contains a fluid and includes a distal end (18), a proximal end (20), and a plunger (24) extending proximally from the proximal end (20). A spray nozzle tip (26) is configured to generate the aerosol and is coupled to the distal end (18) of the syringe (14). The gas-assisted fluid-dispensing device (10) further includes a housing (44) having first and second housing portions (52, 54). The first housing portion (52) includes a docking port (42) for receiving the syringe (14); the second housing portion (54) is configured as a handle. A trigger (50), coupled to the housing (44), is operably coupled to an actuating member (58) that is configured to apply a force onto the plunger (24) of the syringe (14) and discharge the fluid from the syringe (14) and into the spray nozzle tip (26).

Abstract: An apparatus for making and administering two non-homogenous liquids to target tissue includes a spray comprising two syringes for containing the first and second non-homogenous liquid where the syringes are adapted to be removably coupled to an applicator. The applicator includes a pair of elongated tubes each having a tubular sheath at a proximal end, a distal end and a lumen in which the pair of elongated tubes are disposed. The apparatus includes a regulator module having an inlet port adapted for connection to a source of gas under pressure and a gas outlet port adopted for connection to the gas inlet port of the sheet. A vent gas inlet port is adapted for connection to a vent port of an endoscopic cannula where the regulator vents a quantity of gas from the endoscopic cannula approximately equal to a quantity of gas introduced at the gas inlet port of the sheet.

Abstract: An apparatus for equalizing pressure in a middle ear includes a hand-held air source for providing a continuous flow of air at a predetermined rate and a tapered sealing nostril plug adapted to be sealed against a nostril. The tapered nostril plug has a channel there through for delivering the continuous flow of air. The channel of the tapered plug is adapted to be placed in communication with the air source through an adjustable valve assembly for selecting a pressure limit for the air in the channel of the nostril plug.