Patents by Inventor Jon Edelson

Jon Edelson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization
    Patent number: 7326575
    Abstract: This invention relates to methods for the detection of one or more mRNA transcripts in paraffin-embedded tissue by “mRNA liberation in fixed-treated tissue or ‘MLIFTT’”. This method includes treating the tissue with ammonia-ethanol and sodium borohydride combined with pressure cooking of the tissue. The chemical treatments reduce the tissue autofluorescence and the physical treatments overcome the interference created by the fixation-induced chemical bonds. The methods of the present invention can be utilized to identify a plurality of mRNA transcripts in a microarray format.
    Type: Grant
    Filed: November 17, 2005
    Date of Patent: February 5, 2008
    Assignee: Aueron Laboratories, Inc.
    Inventors: Paola Capodieci, Jon Edelson
  • Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization
    Publication number: 20060141502
    Abstract: This invention relates to methods for the detection of one or more mRNA transcripts in paraffin-embedded tissue by “mRNA liberation in fixed-treated tissue or ‘MLIFTT’”. This method includes treating the tissue with ammonia-ethanol and sodium borohydride combined with pressure cooking of the tissue. The chemical treatments reduce the tissue autofluorescence and the physical treatments overcome the interference created by the fixation-induced chemical bonds. The methods of the present invention can be utilized to identify a plurality of mRNA transcripts in a microarray format.
    Type: Application
    Filed: November 17, 2005
    Publication date: June 29, 2006
    Inventors: Paola Capodieci, Jon Edelson
  • Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization
    Patent number: 6995020
    Abstract: This invention relates to methods for the detection of one or more mRNA transcripts in paraffin-embedded tissue by “mRNA liberation in fixed-treated tissue or ‘MLIFTT’”. This method includes treating the tissue with ammonia-ethanol and sodium borohydride combined with pressure cooking of the tissue. The chemical treatments reduce the tissue autofluorescence and the physical treatments overcome the interference created by the fixation-induced chemical bonds. The methods of the present invention can be utilized to identify a plurality of mRNA transcripts in a microarray format.
    Type: Grant
    Filed: July 21, 2003
    Date of Patent: February 7, 2006
    Assignee: Aureon Laboratories, Inc.
    Inventors: Paola Capodieci, Jon Edelson
  • Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization
    Publication number: 20050019779
    Abstract: This invention relates to methods for the detection of one or more mRNA transcripts in paraffin-embedded tissue by “mRNA liberation in fixed-treated tissue or ‘MLIFTT’”. This method includes treating the tissue with ammonia-ethanol and sodium borohydride combined with pressure cooking of the tissue. The chemical treatments reduce the tissue autofluorescence and the physical treatments overcome the interference created by the fixation-induced chemical bonds. The methods of the present invention can be utilized to identify a plurality of mRNA transcripts in a microarray format.
    Type: Application
    Filed: July 21, 2003
    Publication date: January 27, 2005
    Inventors: Paola Capodieci, Jon Edelson