Patents by Inventor Jon M. Steichen

Jon M. Steichen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant HIV Env polypeptides and their use
    Patent number: 12281142
    Abstract: The present disclosure relates to recombinant HIV Env polypeptides and their use in the treatment and prevention of HIV/AIDS.
    Type: Grant
    Filed: June 1, 2021
    Date of Patent: April 22, 2025
    Assignees: International AIDS Vaccine Initiative, Inc., The Scripps Research Institute
    Inventors: Jon M. Steichen, William R. Schief
  • IMMUNOGENIC COMPOSITIONS
    Publication number: 20240226272
    Abstract: Provided herein are glycan engineered SARS-CoV-2 RBD polypeptides, fusion polypeptides comprising thereof, and immunogenic compositions comprising thereof. Also provided are methods of administering the RBD polypeptide, fusion polypeptide or immunogenic composition to a subject to elicit an immune response. Also provided are polynucleotides encoding the fusion polypeptide, and methods of administering a composition comprising the polynucleotide to a subject to elicit an immune response. In some embodiments, the polynucleotide is an RNA comprising modified ribonucleotides.
    Type: Application
    Filed: December 17, 2021
    Publication date: July 11, 2024
    Inventors: William R. SCHIEF, Torben SCHIFFNER, Jon M. STEICHEN, Xiaozhen HU
  • IMMUNOGENIC COMPOSITIONS
    Publication number: 20240131148
    Abstract: Provided herein are glycan engineered SARS-CoV-2 RBD polypeptides, fusion polypeptides comprising thereof, and immunogenic compositions comprising thereof. Also provided are methods of administering the RBD polypeptide, fusion polypeptide or immunogenic composition to a subject to elicit an immune response. Also provided are polynucleotides encoding the fusion polypeptide, and methods of administering a composition comprising the polynucleotide to a subject to elicit an immune response. In some embodiments, the polynucleotide is an RNA comprising modified ribonucleotides.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 25, 2024
    Inventors: William R. SCHIEF, Torben SCHIFFNER, Jon M. STEICHEN, Xiaozhen HU
  • RECOMBINANT HIV ENV POLYPEPTIDES AND THEIR USE
    Publication number: 20210363195
    Abstract: The present disclosure relates to recombinant HIV Env polypeptides and their use in the treatment and prevention of HIV/AIDS.
    Type: Application
    Filed: June 1, 2021
    Publication date: November 25, 2021
    Inventors: Jon M. STEICHEN, William R. SCHIEF
  • FERRITIN NANOPARTICLE DISPLAYING AN HIV TRIMER
    Publication number: 20210363194
    Abstract: The present invention relates to glycosylate HIV timer nanoparticles fused to self-assembling ferritin proteins which may be utilized as immunogens to enhance trafficking to lymph nodes and germinal centers and to heighten immune responses.
    Type: Application
    Filed: June 5, 2019
    Publication date: November 25, 2021
    Inventors: Talar Tokatlian, Benjamin J. Read, Daniel W. Kulp, Sergey Menis, Jon M. Steichen, William R. Schief, Darrell J. Irvine