Abstract: Systems and methods of monitoring the position of semi-autonomous or fully-autonomous devices for safe navigation in a dynamic, unstructured environment can include processes to detect localization errors via an odometry check, a laser map alignment check, or a bimodal distribution check; detect tracking errors to monitor and/or control device trajectory and/or to avoid device rollover; regulate velocity control based on static or dynamic safety zones for collision avoidance; perform system integrity checks to maintain desired performance over time; and/or the like. These processes may interface with and/or utilize sensors on the device and may provide inputs for a safety monitor system that oversees device safety. In addition, an onboard computer system with a real time operating system may be used to enable real time monitoring and response during device navigation and to execute relevant processes associated with this system independent of other processes performed.