Patents by Inventor Jon McGrath
Jon McGrath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230356468Abstract: A system for producing a graft device for a patient may comprise: an imaging device configured to produce image data of a tubular conduit; and a processing unit configured to receive the image data from the imaging device. The processing unit may comprise an algorithm configured to process the image data, and produce a construction signal based on the image data. A material delivery device may be configured to receive the construction signal from the processor, and deliver material to produce a 3D covering based on the construction signal. The graft device may comprise the 3D covering positioned about the tubular conduit. Graft devices and methods of producing graft devices may also be provided.Type: ApplicationFiled: March 10, 2023Publication date: November 9, 2023Inventors: Matthew Mannarino, Jon McGrath, Cory Leeson, Mohammed El-Kurdi, Danielle McDowell, Kermit Santiago, J. Christopher Flaherty
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Publication number: 20230321912Abstract: A system for producing a graft device for a patient may comprise: an imaging device configured to produce image data of a tubular conduit; and a processing unit configured to receive the image data from the imaging device. The processing unit may comprise an algorithm configured to process the image data, and produce a construction signal based on the image data. A material delivery device may be configured to receive the construction signal from the processor, and deliver material to produce a 3D covering based on the construction signal. The graft device may comprise the 3D covering positioned about the tubular conduit. Graft devices and methods of producing graft devices may also be provided.Type: ApplicationFiled: March 10, 2023Publication date: October 12, 2023Inventors: Matthew Mannarino, Jon McGrath, Cory Leeson, Mohammed El-Kurdi, Danielle McDowell, Kermit Santiago, J.Christopher Flaherty
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Publication number: 20210196445Abstract: Provided herein our graft devices for a patient comprising one or more layers, such as an inner layer and an outer layer. The inner layer comprises a first porous arrangement of fibers defining a first tube comprising an inner wall and an outer wall. The outer layer comprises a second porous arrangement of fibers defining a second tube comprising an inner wall and an outer wall. The second tube surrounds the first tube. A plurality of macropores extend through at least the inner and outer wall of the first tube. The inner and/or the outer layer can comprise a biofragmentable material configured to mechanically fracture into one or more fragments over time. Methods of creating graft devices are also disclosed.Type: ApplicationFiled: June 7, 2019Publication date: July 1, 2021Inventors: Mohammed El-Kurdi, Ayotte Ryan, Anh Thi Dinh, Kevin Farrell, Jon McGrath
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Patent number: 10695162Abstract: A system for applying a fiber matrix on a tubular member is provided. A mandrel, configured for atraumatic placement within the tubular member, is included. Methods for atraumatic placement of a mandrel into a tubular member are also provided.Type: GrantFiled: December 15, 2017Date of Patent: June 30, 2020Assignee: Xeltis AGInventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, J. Christopher Flaherty, Liem Vu, Jerry Brightbill, Stephen Evans, Joseph Ting, David Rezac, Timothy Robinson
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Publication number: 20190263068Abstract: A system for producing a graft device for a patient may comprise: an imaging device configured to produce image data of a tubular conduit; and a processing unit configured to receive the image data from the imaging device. The processing unit may comprise an algorithm configured to process the image data, and produce a construction signal based on the image data. A material delivery device may be configured to receive the construction signal from the processor, and deliver material to produce a 3D covering based on the construction signal. The graft device may comprise the 3D covering positioned about the tubular conduit. Graft devices and methods of producing graft devices may also be provided.Type: ApplicationFiled: June 9, 2017Publication date: August 29, 2019Inventors: Matthew MANNARINO, Jon MCGRATH, Cory LEESON, Mohammed EL-KURDI, Danielle CZARNOWSKI, Kermit SANTIAGO, J. Christopher FLAHERTY
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Patent number: 10239071Abstract: A cartridge device is provided for applying a fiber matrix to a tubular member such as a saphenous vein graft. The cartridge includes a housing, a tubular member holder, a rotational drive, and a polymer delivery assembly. The housing defines a chamber which surrounds the tubular member holder. The rotational drive rotates the tubular member during the fiber application process.Type: GrantFiled: August 4, 2016Date of Patent: March 26, 2019Assignees: Neograft Technologies, Inc., University Of Pittsburgh—of the Commonwealth System of Higher EducationInventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, Andrew Ziegler, J. Christopher Flaherty, William R. Wagner, David Vorp
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Publication number: 20180368968Abstract: Provided are systems for applying a polymer fiber matrix to a tubular conduit to create a graft device. The system comprises a polymer solution comprising at least one polymer and at least one solvent; a polymer delivery assembly constructed and arranged to receive the polymer solution and to deliver the polymer fiber matrix to the tubular conduit; a rotating assembly constructed and arranged to rotate at least one of the tubular conduit or the polymer delivery assembly; and a controller constructed and arranged to control the polymer delivery assembly and the rotating assembly. The system is constructed and arranged to reduce the amount of the solvent in the graft device. Methods of applying a polymer fiber matrix with reduced solvent are also provided.Type: ApplicationFiled: December 20, 2016Publication date: December 27, 2018Inventors: Cory LEESON, Matthew MANNARINO, Mohammed EL-KURDI, Jon MCGRATH
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Patent number: 10149750Abstract: A graft device is provided comprising a flow conduit and a surrounding covering. The graft device can connect a first body space and a second body space. In one embodiment, the flow conduit is a vein, such as a harvested saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided are methods of preparing a graft device and connecting the graft device between a first body space and a second body space, such as the aorta and a location on an occluded coronary artery, distal to the occlusion.Type: GrantFiled: February 16, 2016Date of Patent: December 11, 2018Assignee: NEOGRAFT TECHNOLOGIES, INC.Inventors: David Wagner, Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, John T. Garibotto, J. Christopher Flaherty
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Publication number: 20180289466Abstract: A system for applying a fiber matrix on a tubular member is provided. A mandrel, configured for atraumatic placement within the tubular member, is included. Methods for atraumatic placement of a mandrel into a tubular member are also provided.Type: ApplicationFiled: December 15, 2017Publication date: October 11, 2018Inventors: Lorenzo SOLETTI, Mohammed S. EL-Kurdi, Jon Mcgrath, J. Christopher Flaherty, Liem Vu, Jerry Brightbill, Stephen Evans, Joseph Ting, David Rezac, Timothy Robinson
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Patent number: 10085829Abstract: An apparatus is provided for applying a restrictive fiber matrix to a conduit to create a graft device. A rotating assembly rotates the conduit, and a polymer delivery assembly delivers the restrictive fiber matrix. A controller controls the polymer deliver assembly and the rotating assembly.Type: GrantFiled: January 13, 2012Date of Patent: October 2, 2018Assignee: Neograft Technologies, Inc.Inventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, Liem Vu, J. Christopher Flaherty
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Patent number: 10076427Abstract: In some aspects, graft devices for a mammalian patient can include a tubular member comprising a first end; and a fiber matrix surrounding the tubular member, wherein the fiber matrix is designed and constructed to be substantially continuously tapered at the first end to define a diameter that increases as it approaches the first end.Type: GrantFiled: February 13, 2017Date of Patent: September 18, 2018Assignee: Neograft Technologies, Inc.Inventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, J. Christopher Flaherty
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Patent number: 10065352Abstract: A system for electrospinning a fiber matrix on a tubular member includes at least one nozzle, a tubular member in a spaced relationship to the at least one nozzle, and a fluid source for pressurizing a lumen of the tubular member. An electrical potential is applied between the at least one nozzle and either the tubular member or fluid from the fluid source. The electrical potential draws at least one fiber from the at least one nozzle to the tubular member.Type: GrantFiled: April 27, 2017Date of Patent: September 4, 2018Assignees: Neograft Technologies, Inc., University of Pittsburgh—of the Commonwealth System of Higher EducationInventors: Jon McGrath, Lorenzo Soletti, Mohammed S. El-Kurdi, William R. Wagner, J. Christopher Flaherty
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Patent number: 9987120Abstract: In some aspects, a system for applying a fiber matrix on a tubular conduit is provided. The system can include a tubular conduit, a mandrel and a fiber matrix delivery assembly. The mandrel can comprise an elongate shaft and a rolling membrane configured to atraumatically engage the tubular conduit.Type: GrantFiled: September 11, 2015Date of Patent: June 5, 2018Assignee: Neograft Technologies, Inc.Inventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, J. Christopher Flaherty
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Patent number: 9867690Abstract: A system for applying a fiber matrix on a tubular member is provided. A mandrel, configured for atraumatic placement within the tubular member, is included. Methods for atraumatic placement of a mandrel into a tubular member are also provided.Type: GrantFiled: February 8, 2012Date of Patent: January 16, 2018Assignee: NEOGRAFT TECHNOLOGIES, INC.Inventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, J. Christopher Flaherty, Liem Vu, Jerry Brightbill, Stephen Evans, Joseph Ting, David Rezac, Timothy Robinson
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Publication number: 20170326772Abstract: A system for electrospinning a fiber matrix on a tubular member includes at least one nozzle, a tubular member in a spaced relationship to the at least one nozzle, and a fluid source for pressurizing a lumen of the tubular member. An electrical potential is applied between the at least one nozzle and either the tubular member or fluid from the fluid source. The electrical potential draws at least one fiber from the at least one nozzle to the tubular member.Type: ApplicationFiled: April 27, 2017Publication date: November 16, 2017Applicant: University of Pittsburgh - Of The Commonwealth System of Higher EducationInventors: Jon MCGRATH, Lorenzo SOLETTI, Mohammed S. EL-KURDI, William R. WAGNER, J. Christopher FLAHERTY
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Publication number: 20170312100Abstract: In some aspects, graft devices for a mammalian patient can include a tubular member comprising a first end; and a fiber matrix surrounding the tubular member, wherein the fiber matrix is designed and constructed to be substantially continuously tapered at the first end to define a diameter that increases as it approaches the first end.Type: ApplicationFiled: February 13, 2017Publication date: November 2, 2017Inventors: Lorenzo SOLETTI, Mohammed S. EL-KURDI, Jon MCGRATH, J. Christopher FLAHERTY
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Publication number: 20170258609Abstract: Methods and devices for treating a vessel for use in a medical procedure are disclosed. A vein or other vessel can be modified in situ, prior to harvesting. Subsequently, at least a portion of the vessel is removed, and subsequently implanted to treat a patient, typically in a bypass procedure in which the vessel portion fluidly connects a source of oxygenated blood to an occluded artery.Type: ApplicationFiled: January 24, 2017Publication date: September 14, 2017Inventors: Jon MCGRATH, Mohammed S. EL-KURDI, Lorenzo SOLETTI, J. Christopher FLAHERTY
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Patent number: 9656417Abstract: A system for electrospinning a fiber matrix on a tubular member includes at least one nozzle, a tubular member in a spaced relationship to the at least one nozzle, and a fluid source for pressurizing a lumen of the tubular member. An electrical potential is applied between the at least one nozzle and either the tubular member or fluid from the fluid source. The electrical potential draws at least one fiber from the at least one nozzle to the tubular member.Type: GrantFiled: December 22, 2011Date of Patent: May 23, 2017Assignees: Neograft Technologies, Inc., University of Pittsburgh—of the Commonwealth System of Higher EducationInventors: Jon McGrath, Lorenzo Soletti, Mohammed S. El-Kurdi, William R. Wagner, J. Christopher Flaherty
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Patent number: 9603729Abstract: In some aspects, graft devices for a mammalian patient can include a tubular member comprising a first end; and a fiber matrix surrounding the tubular member, wherein the fiber matrix is designed and constructed to be substantially continuously tapered at the first end to define a diameter that increases as it approaches the first end.Type: GrantFiled: December 30, 2014Date of Patent: March 28, 2017Assignee: NEOGRAFT TECHNOLOGIES, INC.Inventors: Lorenzo Soletti, Mohammed S. El-Kurdi, Jon McGrath, J. Christopher Flaherty
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Patent number: 9579224Abstract: Methods and devices for treating a vessel for use in a medical procedure are disclosed. A vein or other vessel can be modified in situ, prior to harvesting. Subsequently, at least a portion of the vessel is removed, and subsequently implanted to treat a patient, typically in a bypass procedure in which the vessel portion fluidly connects a source of oxygenated blood to an occluded artery.Type: GrantFiled: July 24, 2012Date of Patent: February 28, 2017Assignee: Neograft Technologies, Inc.Inventors: Jon McGrath, Mohammed S. El-Kurdi, Lorenzo Soletti, J. Christopher Flaherty