Abstract: The invention of the present disclosure may be a temperature probe comprising a probe body. The probe body may comprise a tip, a tube, a sleeve configured to join the tip and the tube, the sleeve having one or more tapered ends configured to at least partially enter the tip and the tube, and an end, where a cavity may extend from the proximal end to the distal end, and where the cavity may be internal to the tip, the tube, the sleeve, and the end. The temperature probe may comprise a printed circuit board (PCB) comprising a proximal rigid PCB, a flex PCB, and a distal rigid PCB and a temperature sensor disposed within the tip. A battery may be disposed between the proximal rigid PCB and the distal rigid PCB, the battery at least partially surrounded by the flex PCB.

Abstract: A venting system includes a frame and a register cover attached to the frame. The register cover includes a plurality of alternating open areas and air diverting fins vertically orientated on the register cover. Three open areas among the plurality of open areas are disposed proximate a central portion of the register cover. A tool engagement feature is located at the central portion of the register cover and includes a plurality of concave surfaces formed on at least four of the air diverting fins among the plurality of air diverting fins. The tool engagement feature further includes a forwardly projecting knuckle arranged at a center of each of the three open areas disposed at the central portion of the register cover.

Abstract: The invention of the present disclosure may be a temperature probe comprising a probe body. The probe body may comprise a tip, a tube, a sleeve configured to join the tip and the tube, the sleeve having one or more tapered ends configured to at least partially enter the tip and the tube, and an end, where a cavity may extend from the proximal end to the distal end, and where the cavity may be internal to the tip, the tube, the sleeve, and the end. The temperature probe may comprise a printed circuit board (PCB) comprising a proximal rigid PCB, a flex PCB, and a distal rigid PCB and a temperature sensor disposed within the tip. A battery may be disposed between the proximal rigid PCB and the distal rigid PCB, the battery at least partially surrounded by the flex PCB.

Abstract: The present disclosure describes methods of forming thermal barriers or breaks in tubular structures configured for inclusion in a variety of construction products and building features, such as doors and windows. Methods involve using one or more connector members to couple complementary extrusion profiles, which may comprise aluminum or other conductive materials. A low-conductivity material may then be deposited directly over the connector members coupling the extrusion profiles to form thermal barriers therebetween. At least a portion of the extrusion profiles may be knurled to improve the bond strength between the low-conductivity material, which may comprise polyurethane, and the extrusion profiles. Specialized components may be unnecessary to form the thermal barriers, such that the same connector members used to couple the extrusion profiles may be used to form the thermal barriers.

Abstract: The present disclosure describes methods of forming thermal barriers or breaks in tubular structures configured for inclusion in a variety of construction products and building features, such as doors and windows. Methods involve using one or more connector members to couple complementary extrusion profiles, which may comprise aluminum or other conductive materials. A low-conductivity material may then be deposited directly over the connector members coupling the extrusion profiles to form thermal barriers therebetween. At least a portion of the extrusion profiles may be knurled to improve the bond strength between the low-conductivity material, which may comprise polyurethane, and the extrusion profiles. Specialized components may be unnecessary to form the thermal barriers, such that the same connector members used to couple the extrusion profiles may be used to form the thermal barriers.

Abstract: The invention of the present disclosure may be a temperature probe comprising a probe body. The probe body may comprise a tip, a tube, a sleeve configured to join the tip and the tube, the sleeve having one or more tapered ends configured to at least partially enter the tip and the tube, and an end, where a cavity may extend from the proximal end to the distal end, and where the cavity may be internal to the tip, the tube, the sleeve, and the end. The temperature probe may comprise a printed circuit board (PCB) comprising a proximal rigid PCB, a flex PCB, and a distal rigid PCB and a temperature sensor disposed within the tip. A battery may be disposed between the proximal rigid PCB and the distal rigid PCB, the battery at least partially surrounded by the flex PCB.

Abstract: Methods and systems are provided for emissions reduction in a vehicle. In one example, a method includes pre-emptively adjusting engine operating parameters in response to an anticipated emissions causal event. The emissions causal event lasting for less than a threshold period of time or less than a threshold distance.

Abstract: The invention relates to a novel drug delivery vehicle. Various embodiments of the invention provide a hybrid polymerized liposomal nanoparticle comprising both polymerizable lipids and non-polymerizable lipids. Therapeutic agents can be loaded into the polymerized liposomal nanoparticle and targeting agents can be conjugated to the surface of the polymerized liposomal nanoparticle. Also described in the invention are methods, compositions and kits that utilize the hybrid polymerized liposomal nanoparticle to treat disease conditions such as various cancers.

Abstract: The invention relates to a novel drug delivery vehicle. Various embodiments of the invention provide a hybrid polymerized liposomal nanoparticle comprising both polymerizable lipids and non-polymerizable lipids. Therapeutic agents can be loaded into the polymerized liposomal nanoparticle and targeting agents can be conjugated to the surface of the polymerized liposomal nanoparticle. Also described in the invention are methods, compositions and kits that utilize the hybrid polymerized liposomal nanoparticle to treat disease conditions such as various cancers.

Abstract: A venting system includes a frame and a register cover attached to the frame. The register cover includes a plurality of alternating open areas and air diverting fins vertically orientated on the register cover. Three open areas among the plurality of open areas are disposed proximate a central portion of the register cover. A tool engagement feature is located at the central portion of the register cover and includes a plurality of concave surfaces formed on at least four of the air diverting fins among the plurality of air diverting fins. The tool engagement feature further includes a forwardly projecting knuckle arranged at a center of each of the three open areas disposed at the central portion of the register cover.

Abstract: A system for improving an air-quality of a given space serviced by an exit register of an AC system including a base frame device that is configured to engage the exit register, a metal base frame section for engaging the base frame device with a perimeter of the exit register. A register cover device that is configured to magnetically engage the base frame device. The register cover device having a plurality of alternating open space portions, a plurality of air diverting fin segments, and a magnet holder implement. The magnet holder implement includes at least four magnet holders that are disposed on each end corner portion of the register cover device. At least four height adjustable magnets are disposed on each of the magnet holders, wherein each of the height adjustable magnets is configured to magnetically engage the register cover device with the base frame device.

Abstract: Methods and systems are provided for emissions reduction in a vehicle. In one example, a method includes pre-emptively adjusting engine operating parameters in response to an anticipated emissions causal event. The emissions causal event lasting for less than a threshold period of time or less than a threshold distance.

Abstract: A method of applying a non-homogenous catalyst coating to a surface is provided. The method may include partially masking the surface with a first template; applying a first washcoat slurry to those parts of the surface not masked by the first template; partially masking the surface with a second template; and applying a second washcoat slurry to those parts of the surface not masked by the second template.

Abstract: The present disclosure provides TC-83 VEE-derived replicons, alphaviral replicon particles and immunogenic compositions containing TC-83 alphaviral replicon particles which direct the expression of at least one antigen when introduced into a suitable host cell. The TC-83 VEE-derived ARPs described herein are improved in that they are subject to a lower vector-specific immune response than prior art ARPs.

Abstract: The invention relates to a novel drug delivery vehicle. Various embodiments of the invention provide a hybrid polymerized liposomal nanoparticle comprising both polymerizable lipids and non-polymerizable lipids. Therapeutic agents can be loaded into the polymerized liposomal nanoparticle and targeting agents can be conjugated to the surface of the polymerized liposomal nanoparticle. Also described in the invention are methods, compositions and kits that utilize the hybrid polymerized liposomal nanoparticle to treat disease conditions such as various cancers.

Abstract: A system for improving an air-quality of a given space serviced by an exit register of an AC system including a base frame device that is configured to engage the exit register, a metal base frame section for engaging the base frame device with a perimeter of the exit register. A register cover device that is configured to magnetically engage the base frame device. The register cover device having a plurality of alternating open space portions, a plurality of air diverting fin segments, and a magnet holder implement. The magnet holder implement includes at least four magnet holders that are disposed on each end corner portion of the register cover device. At least four height adjustable magnets are disposed on each of the magnet holders, wherein each of the height adjustable magnets is configured to magnetically engage the register cover device with the base frame device.

Abstract: The invention relates to a novel drug delivery vehicle. Various embodiments of the invention provide a hybrid polymerized liposomal nanoparticle comprising both polymerizable lipids and non-polymerizable lipids. Therapeutic agents can be loaded into the polymerized liposomal nanoparticle and targeting agents can be conjugated to the surface of the polymerized liposomal nanoparticle. Also described in the invention are methods, compositions and kits that utilize the hybrid polymerized liposomal nanoparticle to treat disease conditions such as various cancers.

Abstract: The present invention is directed to a remotely controlled welding machine. A remote control uses the welding circuit to transfer information to a welding power source. The information to be communicated to the power source includes welding power source output command information (amperage/voltage control), welding circuit on/off information (power source output contactor control), and power source mode control (constant voltage/constant current). A transmitter transmits the desired welding operational parameters to a receiver disposed in the power source. The transmitter is constructed to use only a small amount of power which, preferably, is supplied by one or two low voltage replaceable and/or rechargeable batteries. Additionally, an open circuit voltage is not created between the power source and an electrode holder when an arc is not present.

Abstract: The present invention is directed to a remotely controlled welding machine. A remote control uses the welding circuit to transfer information to a welding power source. The information to be communicated to the power source includes welding power source output command information (amperage/voltage control), welding circuit on/off information (power source output contactor control), and power source mode control (constant voltage/constant current). A transmitter transmits the desired welding operational parameters to a receiver disposed in the power source. The transmitter is constructed to use only a small amount of power which, preferably, is supplied by one or two low voltage replaceable and/or rechargeable batteries. Additionally, an open circuit voltage is not created between the power source and an electrode holder when an arc is not present.

Abstract: A method of applying a non-homogenous catalyst coating to a surface is provided. The method may include partially masking the surface with a first template; applying a first washcoat slurry to those parts of the surface not masked by the first template; partially masking the surface with a second template; and applying a second washcoat slurry to those parts of the surface not masked by the second template.