Abstract: Embodiments disclosed herein establish the relationship between changes in cardiovascular metrics and a combination of drugs. The relationship is established based on tracing a chain of causality from drug combination to cardiovascular parameters, described by a linear relationship, and from cardiovascular parameters to cardiovascular metrics, by measuring the direction and sensitivity of the hemodynamic changes caused by the changes to the cardiovascular parameters (which in turn is caused by administration of drugs). Some embodiments model myocardial oxygen consumption—which cannot be measured directly—and also establish the relationship between hemodynamic changes to the myocardial oxygen consumption and change in one or more cardiovascular parameters.

Abstract: A data analytics system to authenticate and authorize access to multiple sources of data for access to the multiple data sources for one or more requesting devices. The system may duplicate and/or access rule sets included in the metadata of the corresponding data source and read identifiers of authorized users maintained by each of the multiple data sources. The access rule sets and authenticated identifiers may be synchronized or otherwise correlated to requesting device identifiers maintained by the data analytics system such that, as requests to access data obtained from one or more of the multiple data sources are received, the system may control access to or otherwise manage the requesting devices interactions with the data from the multiple data systems, reducing the authorization and authentication actions needed to be taken or executed by the requesting devices and the data sources.

Abstract: An approach is described for facilitating an outbound call from a calling party and a called party by displaying specific information on the communication device of the called party. The displayed specific information is based on a communication characteristic of the called party, where the communication characteristic includes a language characteristic of the called party. Based on language characteristic of the called party, customized display content is provided to the communications device of the called party, on or prior to the called party being alerted to the requested communication. The customized display content improves the answer rate and the conversion rate of the outbound call.

Abstract: Embodiments disclosed herein may include operations of receiving a plurality of current cardiovascular performance metrics of a patient and a plurality of candidate drugs to be used to reach a plurality of desired cardiovascular performance metrics and determining optimal dosages of the plurality of candidate drugs to reach the plurality of desired cardiovascular performance metrics. The determining may include optimizing a dosage combination of the plurality of candidate drugs to reach a plurality of desired cardiovascular parameters, corresponding to the plurality of desired cardiovascular performance metrics, from a plurality of current cardiovascular parameters corresponding to the plurality of current cardiovascular performance metrics and mapping the plurality of desired cardiovascular performance metrics from the plurality of desired cardiovascular parameters and the plurality' of current cardiovascular performance metrics from the plurality of current cardiovascular parameters.

Abstract: A data analytics system to authenticate and authorize access to multiple sources of data for access to the multiple data sources for one or more requesting devices. The system may duplicate and/or access rule sets included in the metadata of the corresponding data source and read identifiers of authorized users maintained by each of the multiple data sources. The access rule sets and authenticated identifiers may be synchronized or otherwise correlated to requesting device identifiers maintained by the data analytics system such that, as requests to access data obtained from one or more of the multiple data sources are received, the system may control access to or otherwise manage the requesting devices interactions with the data from the multiple data systems, reducing the authorization and authentication actions needed to be taken or executed by the requesting devices and the data sources.

Abstract: An approach is described for facilitating an outbound call from a calling party and a called party by displaying specific information on the communication device of the called party. The displayed specific information is based on a communication characteristic of the called party, where the communication characteristic includes a language characteristic of the called party. Based on language characteristic of the called party, customized display content is provided to the communications device of the called party, on or prior to the called party being alerted to the requested communication. The customized display content improves the answer rate and the conversion rate of the outbound call.

Abstract: Various embodiments are directed toward a system and method for determining an orientation of an implantable medical device (“IMD”) and automatically adjusting a subcutaneous electrocardiogram (“ECG”) signal based on the determined orientation. The method can further include tagging generated SECG signals so as to identify whether a SECG signal had been generated from an implantable monitoring device with its first electrode being superior or inferior relative to its second electrode. Further embodiments can include automatically adjusting the orientation of the generated SECG signals to match that of a preferred orientation.

Abstract: A method and system for distributing contacting information between applications is provided. The system preferably uses an ENUM-type protocol and a middleware tool kit to associate telephone numbers to other identifying information, such as e-mail addresses or URLs for web sites. The system enables the associated contacting information to be shared across multiple applications that may be implemented on a computer or a mobile telephony device. Information is shared only after verification that a requester is authorized to receive the requested contacting information.

Abstract: A method and system for distributing contacting information between applications is provided. The system preferably uses an ENUM-type protocol and a middleware tool kit to associate telephone numbers to other identifying information, such as e-mail addresses or URLs for web sites. The system enables the associated contacting information to be shared across multiple applications that may be implemented on a computer or a mobile telephony device. Information is shared only after verification that a requester is authorized to receive the requested contacting information.

Abstract: This document discusses, among other things, systems and methods to enable physician labels on a remote server and use labels to verify and improve algorithm results. A method comprises using patient data in an automated analysis to obtain a result; receiving a message from the user, wherein the message is related to the result; and using at least a portion of the message to automatically modify the analysis.

Abstract: A method and system for distributing contacting information between applications is provided. The system preferably uses an ENUM-type protocol and a middleware tool kit to associate telephone numbers to other identifying information, such as e-mail addresses or URLs for web sites. The system enables the associated contacting information to be shared across multiple applications that may be implemented on a computer or a mobile telephony device. Information is shared only after verification that a requester is authorized to receive the requested contacting information.

Abstract: Systems and methods for detecting heart failure by monitoring the time-sequence of physiological changes of a subject using a state machine circuit configured to receive information about physiological characteristics of the subject is described. The current state transitions between a first and a second state in response to a first transition trigger. The current state transitions between the second and first states in response to at least one of the expiration of a first timer or ceasing of the first transition trigger. The current state transitions between the second and third states in response to a second transition trigger. The current state transitions between the third and second states in response to at least one of expiration of a second timer or ceasing of the second transition trigger.

Abstract: Various embodiments are directed toward a system and method for determining an orientation of an implantable medical device (“IMD”) and automatically adjusting a subcutaneous electrocardiogram (“ECG”) signal based on the determined orientation. The method can further include tagging generated SECG signals so as to identify whether a SECG signal had been generated from an implantable monitoring device with its first electrode being superior or inferior relative to its second electrode. Further embodiments can include automatically adjusting the orientation of the generated SECG signals to match that of a preferred orientation.

Abstract: A method and system for distributing contacting information between applications is provided. The system preferably uses an ENUM-type protocol and a middleware tool kit to associate telephone numbers to other identifying information, such as e-mail addresses or URLs for web sites. The system enables the associated contacting information to be shared across multiple applications that may be implemented on a computer or a mobile telephony device. Information is shared only after verification that a requester is authorized to receive the requested contacting information.

Abstract: A method and system for distributing contacting information between applications is provided. The system preferably uses an ENUM-type protocol and a middleware tool kit to associate telephone numbers to other identifying information, such as e-mail addresses or URLs for web sites. The system enables the associated contacting information to be shared across multiple applications that may be implemented on a computer or a mobile telephony device. Information is shared only after verification that a requester is authorized to receive the requested contacting information.

Abstract: This document discusses, among other things, systems and methods for predicting heart failure decompensation using within-patient diagnostics. A method comprises detecting an alert status of each of one or more sensors; calculating an alert score by combining the detected alerts; and calculating a composite alert score, the composite alert score being indicative of a physiological condition and comprising a combination of two or more alert scores.

Abstract: Apparatuses and methods of sense arrays with non-uniform patterns are described. One capacitive-sense array includes a first set of electrodes and a second set of electrodes. The first set of electrodes intersect the second set of electrodes to form a unit cells each corresponding to an intersection of a pair of electrodes comprising one electrode from the first set and one electrode from the second set. At one of the second set of electrodes includes a non-uniform conductive pattern including a first region being located at the intersection of the respective unit cell and a distal region being at a location within the respective unit cell that is farther away from the intersection than the first region. The first region includes a first conductive surface area and the distal region includes a second conductive surface area that is greater than the first conductive surface area.

Abstract: Systems and methods for detecting heart failure by monitoring the time-sequence of physiological changes of a subject using a state machine circuit configured to receive information about physiological characteristics of the subject is described. The current state transitions between a first and a second state in response to a first transition trigger. The current state transitions between the second and first states in response to at least one of the expiration of a first timer or ceasing of the first transition trigger. The current state transitions between the second and third states in response to a second transition trigger. The current state transitions between the third and second states in response to at least one of expiration of a second timer or ceasing of the second transition trigger.

Abstract: Systems and methods for detecting heart failure by monitoring the time-sequence of physiological changes of a subject using a state machine circuit configured to receive information about physiological characteristics of the subject is described. The current state transitions between a first and a second state in response to a first transition trigger. The current state transitions between the second and first states in response to at least one of the expiration of a first timer or ceasing of the first transition trigger. The current state transitions between the second and third states in response to a second transition trigger. The current state transitions between the third and second states in response to at least one of expiration of a second timer or ceasing of the second transition trigger.

Abstract: This invention relates to methods to predict and monitor ovulation and fertility in female mammals by measuring the level of free salivary estradiol. Such information may be used to identify the appropriate timing for egg retrieval prior to in vitro fertilization (IVF), insemination procedures, natural or otherwise, and the timing for transfer of embryos. The ability to monitor salivary estradiol levels throughout the estrous cycle, with the optional application of an algorithm, will aid in identifying the peak time of fertility.