Patents by Inventor Jon R. Sauer
Jon R. Sauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9758824Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand.Type: GrantFiled: August 8, 2016Date of Patent: September 12, 2017Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Jon R. Sauer, Bart J. Van Zeghbroeck
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Patent number: 9410923Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand.Type: GrantFiled: June 22, 2015Date of Patent: August 9, 2016Assignee: Life Technologies CorporationInventors: Jon R. Sauer, Bart J. Van Zeghbroeck
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Patent number: 9228976Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand.Type: GrantFiled: September 27, 2013Date of Patent: January 5, 2016Assignee: Life Technologies CorporationInventors: Jon R. Sauer, Bart J. Van Zeghbroeck
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Publication number: 20150284790Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand.Type: ApplicationFiled: June 22, 2015Publication date: October 8, 2015Inventors: Jon R. Sauer, Bart J. Van Zeghbroeck
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Publication number: 20140021048Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand.Type: ApplicationFiled: September 27, 2013Publication date: January 23, 2014Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Jon R. SAUER, Bart J. VAN ZEGHBROECK
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Publication number: 20130264204Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer.Type: ApplicationFiled: September 14, 2012Publication date: October 10, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Jon R. Sauer, Bart J. van Zeghbroeck
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Publication number: 20130068619Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer.Type: ApplicationFiled: September 14, 2012Publication date: March 21, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Jon R. Sauer, Bart J. van Zeghbroeck
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Publication number: 20120199485Abstract: A system and method employ at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region. A method for manufacturing forms such a semiconductor device. The system and method can be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand. The current has characteristics representative of the component of the polymer, such as characteristics representative of the detected base of the DNA or RNA strand.Type: ApplicationFiled: March 1, 2012Publication date: August 9, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Jon R. SAUER, Bart J. Van Zeghbroeck
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Publication number: 20080119366Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand.Type: ApplicationFiled: October 30, 2007Publication date: May 22, 2008Inventors: Jon R. Sauer, Bart J. Van Zeghbroeck
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Patent number: 7001792Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand, proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand.Type: GrantFiled: April 24, 2001Date of Patent: February 21, 2006Assignee: Eagle Research & Development, LLCInventors: Jon R. Sauer, Bart J. van Zeghbroeck
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Publication number: 20030211502Abstract: A system and method employing at least one semiconductor device, or an arrangement of insulating and metal layers, having at least one detecting region which can include, for example, a recess or opening therein, for detecting a charge representative of a component of a polymer, such as a nucleic acid strand, proximate to the detecting region, and a method for manufacturing such a semiconductor device. The system and method can thus be used for sequencing individual nucleotides or bases of ribonucleic acid (RNA) or deoxyribonucleic acid (DNA). The semiconductor device includes at least two doped regions, such as two n-typed regions implanted in a p-typed semiconductor layer or two p-typed regions implanted in an n-typed semiconductor layer. The detecting region permits a current to pass between the two doped regions in response to the presence of the component of the polymer, such as a base of a DNA or RNA strand.Type: ApplicationFiled: October 24, 2002Publication date: November 13, 2003Inventors: Jon R. Sauer, Bart J. van Zeghbroeck
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Patent number: 5034944Abstract: Apparatus for controlling the transition of a number of lasers that are transmitting light to an optical bus from an off state to a sub-threshold bias state so as to minimize the transmission of light from lasers in the sub-threshold bias state. The apparatus places each laser in the sub-threshold bias state a predetermined time before it is to transmit data to the bus; and then, the apparatus places each laser in the off state after the data transmission has occurred. The lasers transmit in a sequential order onto the optical bus.Type: GrantFiled: October 31, 1988Date of Patent: July 23, 1991Assignee: AT&T Bell LaboratoriesInventors: Gary J. Grimes, Lawrence J. Haas, Jon R. Sauer
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Patent number: 4898444Abstract: A non-invasive optical fiber coupler for coupling light into an optical fiber bus through the cladding surrounding the optical fiber bus without bending the optical fiber bus. The coupler comprises a tap optical fiber free end adjacent to and facing a region of straight optical fiber bus with the tap fiber free end and optical fiber bus region encapsulated with a junction media having substantially the same index of refraction as the cladding of the optical fiber bus. Since the bus cladding is not removed nor is the optical fiber bus bent, there is no additional light lost due to the coupler from the optical fiber bus.Type: GrantFiled: November 30, 1988Date of Patent: February 6, 1990Assignees: American Telephone and Telegraph Company, AT&T Information Systems Inc.Inventors: Gary J. Grimes, Lawrence J. Haas, Jon R. Sauer