Patents by Inventor Jon Reel

Jon Reel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Publication number: 20070203108

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: May 12, 2006

Publication date: August 30, 2007

Inventors: Eugene Thorsett, Michael Pleiss, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Bruce Dressman, James Droste, Steven Henry, Russell Stucky, Warren Porter
Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis

Publication number: 20060223761

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease Also disclosed pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: February 2, 2004

Publication date: October 5, 2006

Applicants: Elan Pharmaceuticals, Inc., Eli Lilly & Company

Inventors: James Audia, Thomas Britton, James Droste, Beverly Folmer, George Huffman, Varghese John, Lee Latimer, Thomas Mabry, Jeffrey Nissen, Warren Porter, Jon Reel, Eugene Thorsett, Jay Tung, Jing Wu, Clark Eid, William Scott
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Publication number: 20060079499

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: December 2, 2004

Publication date: April 13, 2006

Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, R. Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Publication number: 20050272666

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: December 2, 2004

Publication date: December 8, 2005

Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, Jeffrey Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Publication number: 20050267150

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: December 3, 2004

Publication date: December 1, 2005

Inventors: Richard Thompson, Stephen Wilkie, Douglas Stack, Eldon Vanmeter, Qing Shi, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, Steven Henry, Stacey McDaniel, Russell Stucky, Warren Porter
CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS

Publication number: 20050215541

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: September 29, 2004

Publication date: September 29, 2005

Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, R. Jeffrey Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Publication number: 20050203080

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: December 12, 2003

Publication date: September 15, 2005

Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, R. Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Publication number: 20050192265

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: December 3, 2004

Publication date: September 1, 2005

Inventors: Richard Thompson, Stephen Wilkie, Douglas Stack, Eldon Vanmeter, Qing Shi, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, Steven Henry, Stacey McDaniel, Russell Stucky, Warren Porter
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Publication number: 20050192269

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: December 3, 2004

Publication date: September 1, 2005

Inventors: Richard Thompson, Stephen Wilkie, Douglas Stack, Eldon Vanmeter, Qing Shi, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, Steven Henry, Stacey McDaniel, Russell Stucky, Warren Porter
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds

Publication number: 20050182046

Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

Type: Application

Filed: February 13, 2004

Publication date: August 18, 2005

Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, R. Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
Purine derivatives as kinase inhibitors

Publication number: 20050090483

Abstract: The present invention provides kinase inhibitors of Formula I.

Type: Application

Filed: March 4, 2003

Publication date: April 28, 2005

Inventors: Thomas Engler, Timothy Burkholder, Joshua Clayton, Clive Diefenbacher, Kelly Furness, James Henry, Yihong Li, Sushant Malhotra, Angela Marquart, Johnathan McLean, David Mendel, Jon Reel