Patents by Inventor Jon S. Jacobs

Jon S. Jacobs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocycles useful in the treatment of alzheimer's disease
    Patent number: 7456163
    Abstract: The present invention is macrocycles of the formula (X): for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme for the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: November 25, 2008
    Assignee: Elan Pharmaceuticals, Inc.
    Inventors: Shon R. Pulley, James P. Beck, Ruth E. TenBrink, Jon S. Jacobs
  • Hydroxypropyl amides for the treatment of Alzheimer's disease
    Patent number: 7262208
    Abstract: The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: August 28, 2007
    Assignees: Elan Pharmaceuticals, Inc., Pharmacia & Upjohn Company
    Inventors: John A. Tucker, Brian A. Sherer, Ying Zi Xu, Louis Brogley, Shon R. Pulley, Jon S. Jacobs, James P. Beck, Varghese John
  • Hydroxypropylamines
    Patent number: 7244755
    Abstract: Disclosed are compounds of formula I: and the pharmaceutically acceptable salts thereof wherein the variables RN, R1, R2, R3, RP and RC are defined herein. These compounds are useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Grant
    Filed: October 4, 2002
    Date of Patent: July 17, 2007
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jed F. Fisher, Jon S. Jacobs, Brian Sherer
  • Macrocycles useful in the treatment of Alzheimer's disease
    Patent number: 7067507
    Abstract: The present invention is macrocycles of the formula (X): for treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme for the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: June 27, 2006
    Assignee: Pharmacia & Upjohn Company
    Inventors: Shon R. Pulley, James P. Beck, Ruth E. TenBrink, Jon S. Jacobs
  • Hydroxypropyl amides for the treatment of Alzheimer's disease
    Publication number: 20040039034
    Abstract: The present invention relates to compounds of formula (I): 1
    Type: Application
    Filed: April 30, 2003
    Publication date: February 26, 2004
    Inventors: John A. Tucker, Brian A. Sherer, Ying Zi Xu, Louis Brogley, Shon R. Pulley, Jon S. Jacobs, James P. Beck, Varghese John
  • Macrocycles useful in the treatment of alzheimer's disease
    Publication number: 20030236240
    Abstract: The present invention is macrocycles of the formula (X): 1
    Type: Application
    Filed: June 13, 2002
    Publication date: December 25, 2003
    Inventors: Shon R. Pulley, James P. Beck, Ruth E. TenBrink, Jon S. Jacobs
  • Hydroxypropylamines
    Publication number: 20030125365
    Abstract: Disclosed are compounds of formula I: 1
    Type: Application
    Filed: October 4, 2002
    Publication date: July 3, 2003
    Inventors: Jed F. Fisher, Jon S. Jacobs, Brian Sherer