Abstract: An electrified vehicle include a chassis, a front axle coupled to the chassis, a rear axle coupled to the chassis, an electric motor supported by the chassis, and a trailer coupled to a rear end of the chassis and configured to be towed by the electrified vehicle. The electric motor is configured to drive at least one of the front axle, the rear axle, or a component of the electrified vehicle. The trailer includes a trailer frame, a trailer axle coupled to the trailer frame, and an energy storage device supported by the trailer frame. The energy storage device includes a plurality of batteries. The energy storage device configured to power the electric motor.

Abstract: A vehicle includes a chassis including a frame rail extending longitudinally, a tractive element coupled to the chassis, an electric motor coupled to the chassis, a shaft coupling the electric motor to the tractive element such that the electric motor is configured to drive the tractive element to propel the vehicle, the shaft extending longitudinally, and a water pump configured to provide a flow of water in response to receiving mechanical energy provided by the electric motor.

Abstract: A vehicle includes a chassis, tractive elements coupled to the chassis, an electric motor coupled to the chassis and coupled to the tractive elements such that the electric motor drives the tractive elements to propel the vehicle, an accessory module coupled to the chassis and coupled to an output of the electric motor. The accessory module is configured to receive mechanical energy provided by the electric motor and provide at least one of electrical energy or fluid energy.

Abstract: Disclosed are compositions and methods for sensitive detection of one or multiple analytes. In general, the methods involve the use of special label components, referred to as reporter signals, that can be associated with, incorporated into, or otherwise linked to the analytes. In some embodiments, the reporter signals can be altered such that the altered forms of different reporter signals can be distinguished from each other. In some embodiments, sets of reporter signals can be used where two or more of the reporter signals in a set have one or more common properties that allow the reporter signals having the common property to be distinguished and/or separated from other molecules lacking the common property.

Abstract: Disclosed are compositions and methods for sensitive detection of one or multiple analytes. In general, the methods involve the use of special label components, referred to as reporter signals, that can be associated with, incorporated into, or otherwise linked to the analytes. In some embodiments, the reporter signals can be altered such that the altered forms of different reporter signals can be distinguished from each other. In some embodiments, sets of reporter signals can be used where two or more of the reporter signals in a set have one or more common properties that allow the reporter signals having the common property to be distinguished and/or separated from other molecules lacking the common property.

Abstract: The present invention provides a polypeptide of 26 amino acid residues that comprises the minimal ankyrin binding (MAB) domain. The MAB domain is responsible for the interactions between a Na,K-ATPase and ankyrin. The present invention also provides the three dimensional structure of the MAB domain. Also provided by the present invention are methods for modulating the interaction of a Na,K-ATPase and ankyrin.

Abstract: A novel cytoplasmic ankyrin protein is disclosed along with methods for selectively identifying ankyrin proteins that participate in the trafficking of integral membrane proteins and secretory proteins between the endoplasmic reticulum, Golgi and other membrane compartments. Nucleic acid and protein sequences are disclosed, along with methods for identifying agents that modulate the binding of ankyrins to their binding partners.