Abstract: Various methods, systems, and devices for treating tissue ablation are disclosed. Some embodiments disclosed herein pertain to methods of treating tumors, systems used for irradiating tissue and tumors with electromagnetic radiation, components and devices of that system, and kits for providing systems used for irradiating tissue and tumors with electromagnetic radiation. In some embodiments, the system provides sub-ablative infrared radiation that is absorbed by nanoparticles. In some embodiments, the nanoparticles absorb the radiation converting it into heat energy. In some embodiments, though the infrared radiation itself may be sub-ablative, the heat energy generated by the nanoparticles is sufficient to cause thermal coagulation, hyperthermia, and/or tissue ablation.

Abstract: Disclosed are apparatuses, systems, and methods for programmable fluidic processors. In one embodiment, the invention involves manipulating droplets across a reaction surface of the processor substantially contact-free of any surfaces. The reaction surface and the electrodes of the processor may include a coating repelling the droplets. Further, the present invention provides for a suitable suspending medium for repelling droplets away from fixed surfaces.

Abstract: Disclosed are apparatuses, systems, and methods for programmable fluidic processors. In one embodiment, the invention involves manipulating droplets across a reaction surface of the processor substantially contact-free of any surfaces. The reaction surface and the electrodes of the processor may include a coating repelling the droplets. Further, the present invention provides for a suitable suspending medium for repelling droplets away from fixed surfaces.

Abstract: Disclosed are apparatuses, systems, and methods for programmable fluidic processors. In one embodiment, the invention involves manipulating droplets across a reaction surface of the processor substantially contact-free of any surfaces. The reaction surface and the electrodes of the processor may include a coating repelling the droplets. Further, the present invention provides for a suitable suspending medium for repelling droplets away from fixed surfaces.

Abstract: Disclosed are apparatuses, systems, and methods for programmable fluidic processors. In one embodiment, the invention involves manipulating droplets across a reaction surface of the processor substantially contact-free of any surfaces. The reaction surface and the electrodes of the processor may include a coating repelling the droplets. Further, the present invention provides for a suitable suspending medium for repelling droplets away from fixed surfaces.

Abstract: Methods and apparatuses for metered injection of a fluid packet. A vessel containing a fluid is pressurized to a pressure less than or equal to a hold-off pressure. The fluid is subjected to an extraction force to form the fluid packet and extract the fluid packet from the vessel onto a surface.

Abstract: A dielectric gate and related systems and methods for controlling fluid flow. A dielectric gate includes one or more electrodes coupled between an inlet fluid pathway and an outlet fluid pathway. The electrodes are configured to draw fluid from the inlet fluid pathway to the outlet fluid pathway in a precise manner by using dielectric forces arising from electrical signals applied to the electrodes.

Abstract: A user interface includes a selection window for allowing a user to select one of a plurality of displayed objects, each of which include at least one identifying attribute. The user interface also includes an administration window disposed adjacent to the section window for displaying a plurality of user-modifiable attributes of a selected object. The selection and administration windows are synchronized such that a user selection of an object in the selection window results in a presentation of one or more attributes of the selected object within the administration window. In the other direction, a user modification of an identifying attribute of an object within the administration window results in a corresponding change to the identifying attribute of the object within the selection window.

Abstract: Devices, systems, and methods for an oligonucleotide synthesis engine. In on embodiment, the invention involves a microfluidic device including: an oligonucleotide synthesis subunit including a reaction surface and means for generating a manipulation force and routing for packet delivery; an analysis or diagnostic subunit; and a control subunit including a program to direct oligonucleotide synthesis. In another embodiment, the invention involves a method for analyzing a sample. An oligonucleotide is synthesized in a solid-phase oligonucleotide synthesis subunit, wherein the subunit includes a reaction surface and means for generating a manipulation force and routing for packet delivery. The synthesis is controlled with a control subunit, wherein the control subunit is programmed for the automatic synthesis of oligonucleotides. The sample is analyzed in an analysis or diagnostic subunit.

Abstract: A dielectric gate and related systems and methods for controlling fluid flow. A dielectric gate includes one or more electrodes coupled between an inlet fluid pathway and an outlet fluid pathway. The electrodes are configured to draw fluid from the inlet fluid pathway to the outlet fluid pathway in a precise manner by using dielectric forces arising from electrical signals applied to the electrodes.

Abstract: Methods and apparatuses for metered injection of a fluid packet. A vessel containing the packet is pressurized to a pressure less than or equal to a hold-off pressure. The packet is subjected to an extraction force to extract the packet from the vessel onto a surface.