Patents by Inventor Jon Silver

Jon Silver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150153345
    Abstract: The subject invention provides an antibody composition for detecting E6 protein of at least one HPV strain in a sample. The subject antibodies may be used to detect oncogenic HPV E6 proteins in a sample, and the antibodies find use in a variety of diagnostic and therapeutic applications, including methods of diagnosing and treating cancer. Kits for performing the subject methods and containing the subject antibodies are also provided. Also disclosed in the present invention is a method of generating an antibody that specifically binds to amino-terminus of E6 proteins of at least two HPV strains.
    Type: Application
    Filed: June 16, 2014
    Publication date: June 4, 2015
    Inventors: Eric Dixon, Rainer Blaesius, Stephen Simkins, Steven L. Knapp, George Brough, Karen Lenz, Johannes Schweizer, Peter Lu, David Garman, Jon Silver, Charles Mahoney, Chamorro Somoza Diaz-Sarmiento
  • Publication number: 20120141502
    Abstract: The subject invention provides an antibody composition for detecting E6 protein of at least one HPV strain in a sample. The subject antibodies may be used to detect oncogenic HPV E6 proteins in a sample, and the antibodies find use in a variety of diagnostic and therapeutic applications, including methods of diagnosing and treating cancer. Kits for performing the subject methods and containing the subject antibodies are also provided. Also disclosed in the present invention is a method of generating an antibody that specifically binds to amino-terminus of E6 proteins of at least two HPV strains.
    Type: Application
    Filed: April 20, 2010
    Publication date: June 7, 2012
    Inventors: Eric Dixon, Rainer Blaesius, Stephen Simkins, Steven L. Knapp, George Brough, Karen Lenz, Johannes Schweizer, Peter Lu, David Garman, Jon Silver, Charles Mahoney, Chamorro Somoza Diaz-Sarmiento
  • Publication number: 20100143884
    Abstract: The present application describes methods for detecting influenza A and/or influenza B and/or distinguishing between pathogenic and seasonal influenza A subtypes. Many of these preferred formats employ pan-specific antibodies (i.e., that react with all or at least multiple strains within an influenza type) to detect presence of influenza A and/or influenza B and PDZ domains in combination with panspecific antibodies to influenza A to distinguish pathogenic and seasonal influenza A subtypes.
    Type: Application
    Filed: January 28, 2008
    Publication date: June 10, 2010
    Applicant: Arbor Vita Corporations
    Inventors: Peter S. Lu, Michael P. Belmares, Johannes Schweizer, Jon Silver
  • Publication number: 20100028855
    Abstract: The invention provides methods for detecting influenza B from its NS1 protein. The NS1 protein is present in detectable levels in clinical samples and can be detected using antibodies that are panspecific for influenza B without binding to influenza A or other viruses.
    Type: Application
    Filed: October 21, 2006
    Publication date: February 4, 2010
    Applicant: Arbor Vista Corporation
    Inventors: Peter S. Lu, Michael P. Belmares, Johannes Schweizer, Jon Silver, Jon Silver
  • Publication number: 20070224594
    Abstract: The present application describes methods for detecting influenza A and/or influenza B and/or distinguishing between pathogenic and seasonal influenza A subtypes. Many of these preferred formats employ pan-specific antibodies (i.e., that react with all or at least multiple strains within an influenza type) to detect presence of influenza A and/or influenza B and PDZ domains in combination with panspecific antibodies to influenza A to distinguish pathogenic and seasonal influenza A subtypes.
    Type: Application
    Filed: January 26, 2007
    Publication date: September 27, 2007
    Applicant: Arbor Vita Corporation
    Inventors: Peter Lu, Michael Belmares, Johannes Schweizer, Jon Silver