Patents by Inventor Jon Steichen

Jon Steichen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNOGENIC TRIMERS
    Publication number: 20240374731
    Abstract: The invention relates to PGT121-germline-targeting designs, trimer stabilization designs, combinations of those two, trimers designed with modified surfaces helpful for immunization regimens, other trimer modifications and on development of trimer nanoparticles and methods of making and using the same.
    Type: Application
    Filed: June 4, 2024
    Publication date: November 14, 2024
    Inventors: Jon Steichen, Dan Kulp, Xiaozhen Hu, Sergey Menis, William Schief, Sebastian Raemisch
  • SARS-COV-2 RBD CONSTRUCTS
    Publication number: 20240247033
    Abstract: The present invention relates to glycan-masked and membrane-tethered SARS-CoV-2 RBD vaccine constructs and methods for making and administering the same. The present invention also encompasses a general vaccine platform for coronaviruses.
    Type: Application
    Filed: June 22, 2021
    Publication date: July 25, 2024
    Inventors: William SCHIEF, Jon STEICHEN, Torben SCHIFFNER, Xiaozhen HU, Christoper COTTRELL
  • MODIFIED IMMUNOGENIC PROTEINS
    Publication number: 20230190914
    Abstract: The invention relates to germline-targeting designs, stabilization designs, and/or combinations thereof, of proteins designed with modified surfaces helpful for immunization regimens, other protein modifications and/or development of nanoparticles, methods of making and using the same, and to (a) germline-targeting priming or boosting/shepherding immunogens to initiate or guide maturation of VRC01-class responses (b) PCT64/PG9-germline-targeting designs (c) BG18-germline-targeting designs or boosting/shepherding immunogens to initiate or guide maturation of BG18-like responses, and/or (d) trimer stabilization and presentation in a membrane-bound format.
    Type: Application
    Filed: October 24, 2022
    Publication date: June 22, 2023
    Inventors: William SCHIEF, Manyuan MA, Jon STEICHEN, Xiaozhen HU, Sebastian RAEMISCH, Alessia LIGUORI, Torben SCHIFFNER, Jordan WILLIS, Christopher COTTRELL
  • IMMUNOGENIC TRIMERS
    Publication number: 20230016284
    Abstract: The invention relates to PGT121-germline-targeting designs, trimer stabilization designs, combinations of those two, trimers designed with modified surfaces helpful for immunization regimens, other trimer modifications and on development of trimer nanoparticles and methods of making and using the same.
    Type: Application
    Filed: August 11, 2021
    Publication date: January 19, 2023
    Inventors: Jon Steichen, Dan Kulp, Xiaozhen Hu, Sergey Menis, William Schief, Sebastian Raemisch
  • Immunogenic trimers
    Patent number: 11203617
    Abstract: The invention relates to PGT121-germline-targeting designs, trimer stabilization designs, combinations of those two, trimers designed with modified surfaces helpful for immunization regimens, other trimer modifications and on development of trimer nanoparticles and methods of making and using the same.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: December 21, 2021
    Assignees: INTERNATIONAL AIDS VACCINE INITIATIVE, THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Jon Steichen, Dan Kulp, Xiaozhen Hu, Sergey Menis, William Schief, Sebastian Raemisch
  • IMMUNOGENIC TRIMERS
    Publication number: 20190085033
    Abstract: The invention relates to PGT121-germline-targeting designs, trimer stabilization designs, combinations of those two, trimers designed with modified surfaces helpful for immunization regimens, other trimer modifications and on development of trimer nanoparticles and methods of making and using the same.
    Type: Application
    Filed: September 24, 2018
    Publication date: March 21, 2019
    Inventors: Jon Steichen, Dan Kulp, Xiaozhen Hu, Sergey Menis, William Schief, Sebastian Raemisch