Abstract: A drilling riser cable management system includes a plurality of clamping mechanisms pre-installed on riser joints and a robotic arm. The robotic arm has a cable handling mechanism that is configured to securely install the cable on each clamping mechanism without relying on human manipulation of the cable during installation.

Abstract: A rotating control device (RCD) system includes a housing having a bore, a first ram assembly supported in the housing, and a second ram assembly supported within the housing. The first ram assembly includes a first ram and a first packer coupled to the first ram, and the second ram assembly includes a second ram and a second packer coupled to the second ram. The RCD system also includes a bearing assembly configured to enable the first packer and the second packer to rotate relative to the first ram and the second ram.

Abstract: A rotating control device (RCD) system includes a housing having a bore, a seal element positioned within the housing, a piston assembly supported within the housing and configured to drive the seal element to seal the bore, and a bearing assembly supported within the housing and configured to enable the seal element to rotate relative to the housing. The bearing assembly includes a first bearing section positioned between the housing and the seal element and a second bearing section positioned between a piston of the piston assembly and the seal element. The piston assembly is configured to selectively actuate the seal element into a first configuration, where the seal element extends into the bore and seals with a tubular therein, and a second configuration, where the seal element extends entirely through the bore and seals the bore without a tubular extending therein.

Abstract: A rotating control device (RCD) includes a housing defining a bore, a seal element supported within the housing and configured to form a seal against a tubular within the bore, and an active material within the housing. The active material is configured to deform upon application of a magnetic field or an electric field to thereby adjust the seal against the tubular.

Abstract: A rotating control device (RCD) system includes a housing having a bore, a first ram assembly supported in the housing, and a second ram assembly supported within the housing. The first ram assembly includes a first ram and a first packer coupled to the first ram, and the second ram assembly includes a second ram and a second packer coupled to the second ram. The RCD system also includes a bearing assembly configured to enable the first packer and the second packer to rotate relative to the first ram and the second ram.

Abstract: A rotating control device (RCD) system includes a housing having a bore, a seal element positioned within the housing, a piston assembly supported within the housing and configured to drive the seal element to seal the bore, and a bearing assembly supported within the housing and configured to enable the seal element to rotate relative to the housing. The bearing assembly includes a first bearing section positioned between the housing and the seal element and a second bearing section positioned between a piston of the piston assembly and the seal element.

Abstract: A rotating control device (RCD) system includes a housing having a bore, a seal element positioned within the housing, a piston assembly supported within the housing and configured to drive the seal element to seal the bore, and a bearing assembly supported within the housing and configured to enable the seal element to rotate relative to the housing. The bearing assembly includes a first bearing section positioned between the housing and the seal element and a second bearing section positioned between a piston of the piston assembly and the seal element.

Abstract: A connector system and method, of which the connector system includes a first conduit having a lower coupling and a first alignment feature, and a frame configured to be coupled to an oilfield tubular, and configured to receive the first conduit and a second conduit. The frame includes a second alignment feature configured to mate with the first alignment feature such that the lower coupling is aligned with the second conduit, and the first alignment feature is configured to slide vertically with respect to the second alignment feature such that the lower coupling is brought into engagement with the second conduit while the first and second alignment features are mated together.

Abstract: A drilling riser cable management system includes a plurality of clamping mechanisms pre-installed on riser joints and a robotic arm. The robotic arm has a cable handling mechanism that is configured to securely install the cable on each clamping mechanism without relying on human manipulation of the cable during installation.

Abstract: A filter has a filter center tube that includes a plurality of layers of solidified material including a first layer with a first undulating strip of solidified material extending in a first predetermined direction, and a second layer with a second undulating strip of solidified material extending in a second predetermined direction. The first layer is in contact with the second layer and the first predetermined direction is not parallel with the second predetermined direction, forming a plurality of pores therebetween.

Abstract: A filter center tube includes a plurality of layers of solidified material including a first layer with a first undulating strip of solidified material extending in a first predetermined direction, and a second layer with a second undulating strip of solidified material extending in a second predetermined direction. The first layer is in contact with the second layer and the first predetermined direction is not parallel with the second predetermined direction, forming a plurality of pores therebetween.

Abstract: A filter center tube includes a plurality of layers of solidified material including a first layer with a first undulating strip of solidified material extending in a first predetermined direction, and a second layer with a second undulating strip of solidified material extending in a second predetermined direction. The first layer is in contact with the second layer and the first predetermined direction is not parallel with the second predetermined direction, forming a plurality of pores therebetween.

Abstract: A prefilled syringe for injecting medicament into a patient includes a barrel constructed of a polymeric material, a cannula and a hub. The barrel has a diameter, a longitudinal axis, a proximal end and a distal end. The cannula has a proximal end and a tip opposite the proximal end. The proximal end of the cannula is fixed to the distal end of the barrel. The cannula is positioned generally coaxially with the longitudinal axis. The hub is integrally formed with the distal end. The hub includes a rib section and a cap. The rib section has a generally cruciform cross-section taken along a rib plane. The rib plane is generally perpendicular to the longitudinal axis. The cap has a generally U-shaped cross-section taken along a longitudinal plane. The longitudinal plane is generally parallel to the longitudinal axis.

Abstract: In one or more embodiments, the present invention provides a novel biomarker which provides a link between a distinct clinical phenotype and a biochemical effect of an autoantibody on an enzyme implicated in disease pathogenesis. In particular, the present invention provides an isolated or purified human autoantibody to PAD3 protein. Methods of diagnosis of subjects for rheumatoid arthritis (RA) using these antibodies as well as diagnosis of the severity of RA in the subject, and methods for monitoring treatment of a subject with RA are also provided. The biomarkers provided herein are also useful in the diagnosis of connective tissue-interstitial lung disease (CT-ILD) in patients having or suspected of having RA.

Abstract: In one or more embodiments, the present invention provides a novel biomarker which provides a link between a distinct clinical phenotype and a biochemical effect of an autoantibody on an enzyme implicated in disease pathogenesis. In particular, the present invention provides an isolated or purified human autoantibody to PAD3 protein. Methods of diagnosis of subjects for rheumatoid arthritis (RA) using these antibodies as well as diagnosis of the severity of RA in the subject, and methods for monitoring treatment of a subject with RA are also provided. The biomarkers provided herein are also useful in the diagnosis of connective tissue-interstitial lung disease (CT-ILD) in patients having or suspected of having RA.

Abstract: In one or more embodiments, the present invention provides a novel biomarker which provides a link between a distinct clinical phenotype and a biochemical effect of an autoantibody on an enzyme implicated in disease pathogenesis. In particular, the present invention provides an isolated or purified human autoantibody to PAD3 protein. Methods of diagnosis of subjects for rheumatoid arthritis (RA) using these antibodies as well as diagnosis of the severity of RA in the subject, and methods for monitoring treatment of a subject with RA are also provided. The biomarkers provided herein are also useful in the diagnosis of connective tissue-interstitial lung disease (CT-ILD) in patients having or suspected of having RA.

Abstract: A prefilled syringe for injecting medicament into a patient includes a barrel constructed of a polymeric material, a cannula and a hub. The barrel has a diameter, a longitudinal axis, a proximal end and a distal end. The cannula has a proximal end and a tip opposite the proximal end. The proximal end of the cannula is fixed to the distal end of the barrel. The cannula is positioned generally coaxially with the longitudinal axis. The hub is integrally formed with the distal end. The hub includes a rib section and a cap. The rib section has a generally cruciform cross-section taken along a rib plane. The rib plane is generally perpendicular to the longitudinal axis. The cap has a generally U-shaped cross-section taken along a longitudinal plane. The longitudinal plane is generally parallel to the longitudinal axis.

Abstract: A prefilled syringe for injecting medicament into a patient includes a barrel constructed of a polymeric material, a cannula and a hub. The barrel has a diameter, a longitudinal axis, a proximal end and a distal end. The cannula has a proximal end and a tip opposite the proximal end. The proximal end of the cannula is fixed to the distal end of the barrel. The cannula is positioned generally coaxially with the longitudinal axis. The hub is integrally formed with the distal end. The hub includes a rib section and a cap. The rib section has a generally cruciform cross-section taken along a rib plane. The rib plane is generally perpendicular to the longitudinal axis. The cap has a generally U-shaped cross-section taken along a longitudinal plane. The longitudinal plane is generally parallel to the longitudinal axis.

Abstract: In one or more embodiments, the present invention provides a novel biomarker which provides a link between a distinct clinical phenotype and a biochemical effect of an autoantibody on an enzyme implicated in disease pathogenesis. In particular, the present invention provides an isolated or purified human autoantibody to PAD3 protein. Methods of diagnosis of subjects for rheumatoid arthritis (RA) using these antibodies as well as diagnosis of the severity of RA in the subject, and methods for monitoring treatment of a subject with RA are also provided. The biomarkers provided herein are also useful in the diagnosis of connective tissue-interstitial lung disease (CT-ILD) in patients having or suspected of having RA.