Patents by Inventor Jon W. Hayenga

Jon W. Hayenga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020148992
    Abstract: A pneumatic valve for use in laminated plastic microfluidic structures. This zero or low dead volume valve allows flow through microfluidic channels for use in mixing, dilution, particulate suspension and other techniques necessary for flow control in analytical devices.
    Type: Application
    Filed: April 3, 2002
    Publication date: October 17, 2002
    Inventors: Jon W. Hayenga, Patrick Saltsman, Bernhard H. Weigl
  • Patent number: 6431212
    Abstract: A valve for use in laminated plastic microfluidic structures. The valve comprises first, second, and third layers of flexible material separated by first and second spacing layers to form microfluidic channels, and having an actuator section to selectively isolate the microfluidic channels from each other. The structure can also be used as a recirculating pump.
    Type: Grant
    Filed: October 2, 2000
    Date of Patent: August 13, 2002
    Inventors: Jon W. Hayenga, Clinton L. Williams
  • Publication number: 20020008032
    Abstract: A device for sensing fluid movement within a microfluidic channel which uses feedback to control its operation. The device measures electric parameters to interpret fluidic parameters such as flow speed, and the presence or absence of fluid within the channel.
    Type: Application
    Filed: June 25, 2001
    Publication date: January 24, 2002
    Inventor: Jon W. Hayenga
  • Patent number: 6130967
    Abstract: A reduced instruction set architecture implements complicated image processing algorithms that are decomposed into combinations of simple operations. The simple operations are further decomposed into multiple operations of one dimensional data with an address controller to scan data in a highly flexible fashion for multi-dimensional applications.
    Type: Grant
    Filed: July 3, 1997
    Date of Patent: October 10, 2000
    Assignee: Tri Path Imaging, Inc.
    Inventors: Shih-Jong J. Lee, Jon W. Hayenga
  • Patent number: 6067370
    Abstract: A method for checking cytological system illumination including the steps of checking global illumination variation, static field uniformity, dynamic field uniformity, specimen thickness variation, strobe repeatability, calibration plate cleanliness, and strobe dropout. A calibration plate and test target is employed for various illumination checks.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: May 23, 2000
    Assignee: TriPath Imaging, Inc.
    Inventors: William E. Ortyn, Louis R. Piloco, Jon W. Hayenga
  • Patent number: 6011861
    Abstract: A method for checking cytological system illumination including the steps of checking global illumination variation, static field uniformity, dynamic field uniformity, specimen thickness variation, strobe repeatability, calibration plate cleanliness, and strobe dropout. A calibration plate and test target is employed for various illumination checks.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: January 4, 2000
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Louis R. Piloco, Jon W. Hayenga
  • Patent number: 5995680
    Abstract: A method for checking cytological system illumination including the steps of checking global illumination variation, static field uniformity, dynamic field uniformity, specimen thickness variation, strobe repeatability, calibration plate cleanliness, and strobe dropout. A calibration plate and test target is employed for various illumination checks.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: November 30, 1999
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Louis R. Piloco, Jon W. Hayenga
  • Patent number: 5991462
    Abstract: A method for checking cytological system illumination including the steps of checking global illumination variation, static field uniformity, dynamic field uniformity, specimen thickness variation, strobe repeatability, calibration plate cleanliness, and strobe dropout. A calibration plate and test target is employed for various illumination checks.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: November 23, 1999
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Louis R. Piloco, Jon W. Hayenga
  • Patent number: 5991432
    Abstract: A method for checking cytological system illumination including the steps of checking global illumination variation, static field uniformity, dynamic field uniformity, specimen thickness variation, strobe repeatability, calibration plate cleanliness, and strobe dropout. A calibration plate and test target is employed for various illumination checks.
    Type: Grant
    Filed: August 15, 1997
    Date of Patent: November 23, 1999
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Louis R. Piloco, Jon W. Hayenga
  • Patent number: 5933519
    Abstract: The invention detects areas of interest at low magnification, locating possible abnormal cells or other cells of interest using image processing and statistical pattern recognition techniques. Next, at high magnification, the areas identified at low magnification are re-examined. The information from the low magnification and high magnification scans is collated and a determination is made about the slide--whether it is normal, abnormal, contains endocervical component, and so forth. The invention also provides a method and apparatus to train object feature and slide feature classifiers. The invention provides an automated cytology system that can process training slides for use in a feed back classifier development environment. The invention also can classify endocervical groups of cells.
    Type: Grant
    Filed: June 3, 1997
    Date of Patent: August 3, 1999
    Assignee: Neo Path, Inc.
    Inventors: Shih-Jong J. Lee, Paul S. Wilhelm, Michael G. Meyer, Wendy R. Bannister, Chih-Chau L. Kuan, William E. Ortyn, Larry A. Nelson, Keith L. Frost, Jon W. Hayenga
  • Patent number: 5912699
    Abstract: A high speed image capture apparatus includes a camera with an integration period between consecutive flashes of an illuminating light pulse, where the camera has an image read out period and an image output. A timer for provides a strobe output representative of the start of a flash. An image capture apparatus captures a first image during the integration period and a second image within a predetermined time after capturing the first image but before the image read out period has elapsed so as to substantially increase a rate of producing usable image outputs. The image capture apparatus is coupled to the strobe output and the image output.
    Type: Grant
    Filed: September 7, 1994
    Date of Patent: June 15, 1999
    Assignee: NeoPath, Inc.
    Inventors: Jon W. Hayenga, Louis R. Piloco
  • Patent number: 5892218
    Abstract: An automated method for checking cytological system autofocus integrity. The automated method includes the steps of checking focus illumination integrity, checking focus camera Modulation Transfer Function, checking focus camera position integrity, and checking closed loop accuracy. Checking focus illumination integrity includes checking focus illumination system integrity, and checking a focus noise floor level. Checking focus camera position integrity includes checking focus camera longitudinal separation, and checking focus camera lateral separation. Checking focus camera position integrity includes checking focus filter frequency response.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: April 6, 1999
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Jon W. Hayenga, Louis R. Piloco
  • Patent number: 5877489
    Abstract: An automated method for checking cytological system autofocus integrity. The automated method includes the steps of checking focus illumination integrity, checking focus camera Modulation Transfer Function, checking focus camera position integrity, and checking closed loop accuracy. Checking focus illumination integrity includes checking focus illumination system integrity, and checking a focus noise floor level. Checking focus camera position integrity includes checking focus camera longitudinal separation, and checking focus camera lateral separation. Checking focus camera position integrity includes checking focus filter frequency response.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: March 2, 1999
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Jon W. Hayenga, Louis R. Piloco
  • Patent number: 5875258
    Abstract: A suite of tests and parameter monitoring methods for at least five major subsystems that are found in most automated image processing systems, as well as calibration routines for three major system functions. The five areas of subsystem verification include processing quality, illumination quality, image collection quality, autofocus quality, and position quality. An automated biological specimen analysis system uses self measures of system parameters to provide a system status. The system status is reported to the user.
    Type: Grant
    Filed: August 26, 1996
    Date of Patent: February 23, 1999
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Louis R. Piloco, Jon W. Hayenga
  • Patent number: 5841124
    Abstract: An automated method for checking cytological system autofocus integrity. The automated method includes the steps of checking focus illumination integrity, checking focus camera Modulation Transfer Function, checking focus camera position integrity, and checking closed loop accuracy. Checking focus illumination integrity includes checking focus illumination system integrity, and checking a focus noise floor level. Checking focus camera position integrity includes checking focus camera longitudinal separation, and checking focus camera lateral separation. Checking focus camera position integrity includes checking focus filter frequency response.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: November 24, 1998
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Jon W. Hayenga, Louis R. Piloco
  • Patent number: 5763871
    Abstract: An automated method for checking cytological system autofocus integrity. The automated method includes the steps of checking focus illumination integrity, checking focus camera Modulation Transfer Function, checking focus camera position integrity, and checking closed loop accuracy. Checking focus illumination integrity includes checking focus illumination system integrity, and checking a focus noise floor level. Checking focus camera position integrity includes checking focus camera longitudinal separation, and checking focus camera lateral separation. Checking focus camera position integrity includes checking focus filter frequency response.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: June 9, 1998
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Jon W. Hayenga, Louis R. Piloco
  • Patent number: 5760387
    Abstract: An automated method for checking cytological system autofocus integrity. The automated method includes the steps of checking focus illumination integrity, checking focus camera Modulation Transfer Function, checking focus camera position integrity, and checking closed loop accuracy. Checking focus illumination integrity includes checking focus illumination system integrity, and checking a focus noise floor level. Checking focus camera position integrity includes checking focus camera longitudinal separation, and checking focus camera lateral separation. Checking focus camera position integrity includes checking focus filter frequency response.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: June 2, 1998
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Jon W. Hayenga, Louis R. Piloco
  • Patent number: 5715326
    Abstract: A method for checking cytological system illumination including the steps of checking global illumination variation, static field uniformity, dynamic field uniformity, specimen thickness variation, strobe repeatability, calibration plate cleanliness, and strobe dropout. A calibration plate and test target is employed for various illumination checks.
    Type: Grant
    Filed: September 8, 1994
    Date of Patent: February 3, 1998
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Louis R. Piloco, Jon W. Hayenga
  • Patent number: 5677762
    Abstract: An illumination device provides temporally, spatially and angularly stable illumination for microscopic evaluations. An arc lamp serves as the light source. An input optical train gathers and focuses the light through an aperture stop to place an image of the arc incident on an input aperture of a light pipe. The magnification of the arc lamp is chosen to reduce the variation due to occlusion. The light pipe spatially homogenizes the light while preserving the angular integrity. An exit window may be placed over the exit aperture of the light pipe to keep dust and debris out of focus. Another optical train receives the spatially homogenized, angularly preserved light and may focus a many arclet images to fill the pupil of a condenser lens. The condenser lens also may focus the exit aperture of the light pipe onto or near the specimen on a microscope slide. A feedback system samples the light and corrects for residual temporal variations by electronically modifying the image as it leaves a CCD.
    Type: Grant
    Filed: May 16, 1996
    Date of Patent: October 14, 1997
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Jon W. Hayenga, Louis R. Piloco
  • Patent number: 5654535
    Abstract: An automated method for checking cytological system autofocus integrity. The automated method includes the steps of checking focus illumination integrity, checking focus camera Modulation Transfer Function, checking focus camera position integrity, and checking closed loop accuracy. Checking focus illumination integrity includes checking focus illumination system integrity, and checking a focus noise floor level. Checking focus camera position integrity includes checking focus camera longitudinal separation, and checking focus camera lateral separation. Checking focus camera position integrity includes checking focus filter frequency response.
    Type: Grant
    Filed: June 19, 1996
    Date of Patent: August 5, 1997
    Assignee: NeoPath, Inc.
    Inventors: William E. Ortyn, Jon W. Hayenga, Louis R. Piloco