Abstract: A cannula for use in transferring small volumes of fluid materials, such as in a parallel reaction process. The cannula comprises a long thin needle having various end (port) configurations, and an adapter for connecting the needle to a fluid line. The adapter may include the combination of a reservoir and transition, or simply a transition.

Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including slurries, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.

Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including slurries, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.

Abstract: An apparatus for parallel processing of multiple reaction mixtures comprises a plurality of reactor vessels for holding reaction mixtures at pressures of at least about 15 psig. Cannula passages communicate with respective vessels, and a cannula is adapted to be inserted into each cannula passage. A sealing mechanism, comprising a valve and a seal, in each cannula passage maintains a respective vessel sealed when the cannula is inserted into and withdrawn from the cannula passage. A robot system is operable to insert the cannula to a location where a distal end and port of the cannula are past the open valve and seal, and to withdraw the cannula. Methods for transferring fluid reaction material to and from a series of pressurized vessels, establishing fluid communication between a cannula and a vessel of a combinatorial chemistry reactor and establishing fluid communication between a cannula and a series of pressurized vessels of a combinatorial chemistry reactor are also disclosed.

Abstract: A cannula for use in transferring small volumes of fluid materials, such as in a parallel reaction process. The cannula comprises a long thin needle having various end (port) configurations, and an adapter for connecting the needle to a fluid line. The adapter may include the combination of a reservoir and transition, or simply a transition.

Abstract: A parallel reactor system including a reactor and vessels in the reactor for holding reaction mixtures, and a cannula for introducing fluid reaction material into the vessels. A robot system is operable to insert the cannula into cannula passages in the reactor for delivery of reaction materials, including slurries, to respective vessels, and to withdraw the cannula from the cannula passages after delivery. Related methods are also disclosed.