Patents by Inventor Jonas A. Gylys

Jonas A. Gylys has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimigraine derivatives of indolylcycloalkanylamines
    Patent number: 5583149
    Abstract: A series of novel serotonergic indolyl derivatives of cycloalkanyl- and cycloalkenyl-amines of Formula I are intended for use in the alleviation of vascular headaches.
    Type: Grant
    Filed: August 21, 1995
    Date of Patent: December 10, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joseph A. Cipollina, Jonas A. Gylys, Ronald J. Mattson, Charles P. Sloan
  • Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines
    Patent number: 5521188
    Abstract: A series of novel 5-cyclobutenedione derivatives of indolylalkylpiperazinyl pyridines and pyrimidines of Formula I are intended for use in the alleviation of vascular headaches.
    Type: Grant
    Filed: July 25, 1994
    Date of Patent: May 28, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jonas A. Gylys, Edward H. Ruediger, David W. Smith, Carola Solomon, Joseph P. Yevich, Pierre Dextraze
  • Antimigraine derivatives of indolylcycloalkanylamines
    Patent number: 5468768
    Abstract: A series of novel serotonergic indolyl derivatives of cycloalkanyl- and cycloalkenyl-amines of Formula I are intended for use in the alleviation of vascular headaches.
    Type: Grant
    Filed: January 6, 1994
    Date of Patent: November 21, 1995
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joseph A. Cipollina, Jonas A. Gylys, Ronald J. Mattson, Charles P. Sloan
  • Antimigraine cyclobutenedione derivatives of tryptamines
    Patent number: 5382592
    Abstract: A series of serotonergic 5-cyclobutenedionylamino-substituted tryptamine derivatives of Formula I is disclosed for use in the alleviation of vascular headaches. ##STR1## The formula I substituents, as further defined in the specification, are: R.sup.1 is hydrogen, halogen, and alkyl; R.sup.2 and R.sup.3 can be hydrogen or alkyl; R.sup.4 is hydrogen, alkyl, acyl or alkylsulfonyl; m is 0 to 3 and n is 1 to 5; and X is amino, alkoxy, hydrogen, alkyl, aryl or alkylaryl.
    Type: Grant
    Filed: September 16, 1993
    Date of Patent: January 17, 1995
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jonas A. Gylys, Edward H. Ruediger, David W. Smith, Carola Solomon, Joseph P. Yevich