Abstract: A method of producing a preformed pavement marking prior to application to paving on the ground comprises: providing a first sheet (10a) of thermoplastic pavement marking material; providing a second sheet (10b) of thermoplastic pavement marking material; positioning the first and second sheets (10a, 10b) next to each other; transferring energy to an energization zone (28) along an edge of at least one of said first and second sheets (10a; 10b), to locally liquefy a portion of the thermoplastic material of said at least one of the first and second thermoplastic pavement marking material sheets (10a, 10b) in the energization zone (28); and solidifying the liquefied thermoplastic of the energization zone (28) to form a bond between the first and second sheets (10a, 10b).

Abstract: The present disclosure relates to a reclosable sealing arrangement for a garment, comprising inter-connectable first tubular portion and second tubular portion for encircling a body portion of a user, a releasable connection system having a first annular connection member extending circumferentially around the first tubular portion and a second annular connection member extending circumferentially around the second tubular portion, whereby the releasable connection system is configured to interconnect said first tubular portion with said second tubular portion, and wherein the reclosable sealing arrangement further comprises a first annular seal member extending circumferentially around the first tubular portion and a second annular seal member extending circumferentially around the second tubular portion to form a fluid-tight seal configuration for the releasable connection system when said first annular connection member is inter-connected to said second annular connection member.

Abstract: A method of producing a preformed pavement marking prior to application to paving on the ground comprises: providing a first sheet (10a) of thermoplastic pavement marking material; providing a second sheet (10b) of thermoplastic pavement marking material; positioning the first and second sheets (10a, 10b) next to each other; transferring energy to an energization zone (28) along an edge of at least one of said first and second sheets (10a; 10b), to locally liquefy a portion of the thermoplastic material of said at least one of the first and second thermoplastic pavement marking material sheets (10a, 10b) in the energization zone (28); and solidifying the liquefied thermoplastic of the energization zone (28) to form a bond between the first and second sheets (10a, 10b).

Abstract: A sealing arrangement for garments to sealingly connect an annular layer and a wearable layer to the sealing arrangement includes a sealing device and a reinforcement clip. The sealing device includes an annular sealing body and an annular base having inner and outer annular wall portions at least partly defining a recess in the annular base. The sealing device includes an annular sealing surface for sealingly connecting the annular layer to the annular base, and the annular sealing body is adapted to be locked into the recess to sealingly connect the wearable layer between the annular base and the annular sealing body. The reinforcement clip includes a sealing device locking portion arranged to be locked to the annular base, and a counteracting portion configured to, in use, counteract a relative movement of the outer and inner annular wall portions.

Abstract: The present inventive concept relates to a sealing arrangement for garments to sealingly connect an annular layer and a wearable layer to the sealing arrangement. The sealing arrangement comprises a sealing device and a reinforcement clip. The sealing device comprises an annular sealing body and an annular base, the latter having inner and outer annular wall portions at least partly defining a recess in the annular base. The sealing device comprises an annular sealing surface for circumferentially and sealingly connecting the annular layer to the annular base, and the annular sealing body is adapted to be locked into the recess to circumferentially and sealingly connect the wearable layer between the annular base and the annular sealing body.

Abstract: The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood com-Components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood or blood components. The present invention further relates to a process for covalent end point attachment of full length heparin to a solid substrate.

Abstract: The present inventive concept relates to a sealing device (1) for garments to sealingly connect an annular layer (3) and a wearable layer (5) to the sealing device (1). The sealing device (1) comprises an annular base (10) having an inner annular wall portion (12) and an outer annular wall portion (14), a recess (30) at least partly defined by the inner annular wall portion (12) and the outer annular wall portion (14), and an annular sealing surface (40) for circumferentially and sealingly connecting the annular layer (3) to the annular base (10). The sealing device (1) further comprises an annular sealing body (60) adapted to be locked into the recess (30) to circumferentially and sealingly connect the wearable layer (5) between the annular base (10) and the annular sealing body (60).

Abstract: The present inventive concept relates to a sealing device (1) for garments to sealingly connect an annular layer (3) and a wearable layer (5) to the sealing device (1). The sealing device (1) comprises an annular base (10) having an inner annular wall portion (12) and an outer annular wall portion (14), a recess (30) at least partly defined by the inner annular wall portion (12) and the outer annular wall portion (14), and an annular sealing surface (40) for circumferentially and sealingly connecting the annular layer (3) to the annular base (10). The sealing device (1) further comprises an annular sealing body (60) adapted to be locked into the recess (30) to circumferentially and sealingly connect the wearable layer (5) between the annular base (10) and the annular sealing body (60).

Abstract: A chimeric protein is made from the combination of (i) a pathogen recognition module derived from a scavenger receptor and (ii) an anchor domain from a different scavenger receptor. The chimeric protein binds to specific pathogens and is useful in various treatments.

Abstract: Mechanisms for complications of renal failure and processes for treating the same are disclosed. They include contacting a biological fluid (e.g. blood) with a filter body, the filter body having immobilized thereon either a CD36 receptor or a CD36 receptor fragment or a SCARB1 receptor or a SCARB1 receptor fragment, the blood having a reduced quantity of oxidatively modified proteins after contacting the filter body. They also include administering an antagonist drug to a patient that blocks the binding activity of the RAGE receptor or the CD36 receptor or the SCARB1 receptor. Diagnostic methods are also provided.

Abstract: The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood com-Components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood or blood components. The present invention further relates to a process for covalent end point attachment of full length heparin to a solid substrate.

Abstract: The present invention relates to a device for extracorporeal removal of harmful agents from blood or blood components, comprising full length heparin immobilized on a solid substrate by covalent end point attachment. The present invention also relates to a method for extracorporeal removal of a harmful agent from mammalian blood or blood components. The present invention further relates to a process for covalent end point attachment of full length heparin to a solid substrate.

Abstract: A separation medium is provided, comprising at least one megalin polypeptide and/or at least one cubilin polypeptide immobilized on a support. Also provided are devices comprising the separation medium, as well as methods and uses employing the separation medium for extracorporeal removal of low molecular weight proteins, or fragments or derivatives thereof, from complex biological fluids.