Patents by Inventor Jonas Helma

Jonas Helma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Means and methods for site-specific functionalization of polypeptides
    Patent number: 10745437
    Abstract: The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: August 18, 2020
    Assignees: LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN, FORSCHUNGSVERBUND BERLIN E.V.
    Inventors: Heinrich Leonhardt, Jonas Helma, Dominik Schumacher, Christian Hackenberger
  • MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES
    Publication number: 20190337977
    Abstract: The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.
    Type: Application
    Filed: December 19, 2018
    Publication date: November 7, 2019
    Inventors: Heinrich LEONHARDT, Jonas HELMA, Dominik SCHUMACHER, Christian HACKENBERGER
  • CHEMOSELECTIVE THIOL-CONJUGATION WITH ALKENE OR ALKYNE-PHOSPHONAMIDATES
    Publication number: 20190330264
    Abstract: Disclosed are novel conjugates and processes for the preparation thereof. A process for the preparation of alkene- or alkyne-phosphonamidates comprises the steps of (I) reacting a compound of formula (III), with an azide of formula (IV), to prepare a compound of formula (V), reacting a compound of formula (V) with a thiol-containing molecule of formula (VI), resulting in a compound of formula (VII).
    Type: Application
    Filed: September 1, 2017
    Publication date: October 31, 2019
    Inventors: Christian Hackenberger, Marc André Kasper, Maria Glanz, Tom Sauer, Dominik Schumacher, Jonas Helma-Smets, Heinrich Leonhardt, Andreas Stengl
  • UNUSUAL SUBSTRATES OF TUBULIN TYROSINE LIGASE
    Publication number: 20190144493
    Abstract: The present invention provides means and methods for functionalizing a polypeptide of interest at its C-terminus with an amino acid derivative.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 16, 2019
    Inventors: Christian HACKENBERGER, Dominik SCHUMACHER, Jonas HELMA, Heinrich LEONHARDT
  • Means and methods for site-specific functionalization of polypeptides
    Patent number: 10208084
    Abstract: The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: February 19, 2019
    Assignees: LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN, FORSCHUNGSVERBUND BERLIN E.V.
    Inventors: Heinrich Leonhardt, Jonas Helma, Dominik Schumacher, Christian Hackenberger
  • MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES
    Publication number: 20170349625
    Abstract: The present invention provides means and methods for equipping a polypeptide of interest at its C-terminus with a versatile adaptor amino acid that allows the functionalization of the polypeptide of interest.
    Type: Application
    Filed: October 29, 2015
    Publication date: December 7, 2017
    Inventors: Heinrich Leonhardt, Jonas Helma, Dominik Schumacher, Christian Hackenberger