Patent number: 9322000
Abstract: The present invention relates to a nucleic acid molecule, which encodes a polypeptide having alcohol dehydrogenase activity, in particular methanol dehydrogenase activity, comprising having a nucleotide sequence selected from the group consisting of: (i) a nucleotide sequence as set forth in any one of SEQ ID NOs: 1 (mdh2-MGA3), 3 (mdh3-MGA3), or 5 (mdh2-PB1); (ii) a nucleotide sequence having at least 90% sequence identity, more particularly at least 91, 92, 93, 94, 95, 96, 97, 98 or 99% sequence identity, with a nucleotide sequence as set forth in any one of SEQ ID NOs: 1, 3 or 5; (iii) a nucleotide sequence which is degenerate with any one of the nucleotide sequences of SEQ ID NOs: 1, 3 or 5; (iv) a nucleotide sequence which is a part of the nucleotide sequence of any one of SEQ ID NOs: 1, 3 or 5, or of a nucleotide sequence which is degenerate with a sequence of SEQ ID NOs: 1, 3 or 5; (v) a nucleotide sequence encoding all or part of a polypeptide whose amino acid sequence is set forth in any one of SEQ I
Type:
Grant
Filed:
January 25, 2013
Date of Patent:
April 26, 2016
Assignees:
SINTEF TTO AS, ETH ZURICH, RIJKSUNIVERSITEIT GRONINGEN
Inventors:
Trygve Brautaset, Tonje Marita Bjerkan Heggeset, Anne Krog, Wilhelmus Johannes Quax, Mark Jan Jacobus Bernhard Sibbald, Julia Vorholt, Jonas Müller, Patrick Kiefer, Eva Potthoff, Volker F Wendisch, Lennart Lessmeier, Stéphanie Heux, Jean-Charles Portais