Patents by Inventor Jonas Malmström

Jonas Malmström has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2-carboxamide-4-piperazinyl-benzofuran derivative
    Patent number: 9012457
    Abstract: The present invention relates to a compound of formula (I), and to pharmaceutical compositions containing said compound and to the use of said compound in therapy, for instance in treating cognitive disorders, as well as to intermediates useful in the preparation thereof.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: April 21, 2015
    Assignee: AstraZeneca AB
    Inventors: Helena Gybäck, Jonas Malmström, Elgaard Gitte Terp
  • 2-CARBOXAMIDE-4-PIPERAZINYL-BENZOFURAN DERIVATIVE
    Publication number: 20140329830
    Abstract: The present invention relates to a compound of formula (I), and to pharmaceutical compositions containing said compound and to the use of said compound in therapy, for instance in treating cognitive disorders, as well as to intermediates useful in the preparation thereof.
    Type: Application
    Filed: December 19, 2011
    Publication date: November 6, 2014
    Applicant: AstraZeneca AB
    Inventors: Helena Gybäck, Jonas Malmström, Elgaard Gitte Terp
  • 2-carboxamide-7-piperazinyl-benzofuran derivatives 774
    Patent number: 8367676
    Abstract: The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted; R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocyclyl, C1-4alkylheterocyclyl, heterocyclyl-heteroaryl, aryl-heterocyclyl, carbocyclyl-heteroaryl, heterocyclyl-aryl, optionally substituted; R3 is hydrogen or C1-4alkyl, or R2 and R3 may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms, and optionally substituted; R4 is hydrogen, halogen, methyl or methoxy; to pharmaceutical composition containing said compounds and to the use of said compounds in therapy, for instance in treating cognitive disorders. The present invention further relates to new intermediates useful in the preparation thereof.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: February 5, 2013
    Assignee: AstraZeneca AB
    Inventors: Johan Andersson, Helena Gybäck, Anh Johansson, Christian Erik Linde, Jonas Malmström, Gunnar Nordvall, Tatjana Weigelt, Gitte Terp
  • Novel Heteroaryl Substituted Benzothiazoles
    Publication number: 20120207679
    Abstract: The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses for such compounds, having the structural formula (I) below: and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzothiazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.
    Type: Application
    Filed: April 23, 2012
    Publication date: August 16, 2012
    Applicant: ASTRAZENECA AB
    Inventors: Ylva Gravenfors, Catrin Jonasson, Jonas Malmström, Gunnar Nordvall, David Pyring, Can Slivo, Daniel Sohn, Peter Ström, David Wensbo
  • 2-CARBOXAMIDE-7-PIPERAZINYL-BENZOFURAN DERIVATIVES 774
    Publication number: 20100331341
    Abstract: The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted; R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocyclyl, C1-4alkylheterocyclyl, heterocyclyl-heteroaryl, aryl-heterocyclyl, carbocyclyl-heteroaryl, heterocyclyl-aryl, optionally substituted; R3 is hydrogen or C1-4alkyl, or R2 and R3 may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms, and optionally substituted; R4 is hydrogen, halogen, methyl or methoxy; to pharmaceutical composition containing said compounds and to the use of said compounds in therapy, for instance in treating cognitive disorders. The present invention further relates to new intermediates useful in the preparation thereof.
    Type: Application
    Filed: June 28, 2010
    Publication date: December 30, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Johan ANDERSSON, Helena GYBÄCK, Anh JOHANSSON, Christian Erik LINDE, Jonas MALMSTRÖM, Gunnar NORDVALL, Tatjana WEIGELT, Gitte TERP