Patents by Inventor Jonas Malmstrom
Jonas Malmstrom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180201592Abstract: The invention provides a compound which is a diazine of formula (I) or a tautomer thereof, or a pharmaceutically acceptable salt thereof, for use as an antifungal agent: (I) wherein X, N?, C?, A and E are as defined herein. The invention also provides a compound of Formula (I) as defined herein.Type: ApplicationFiled: July 14, 2016Publication date: July 19, 2018Inventors: Graham Edward Morris SIBLEY, Lars Jonas MALMSTRÖM, Johanna Maria LARSSON
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Patent number: 9012457Abstract: The present invention relates to a compound of formula (I), and to pharmaceutical compositions containing said compound and to the use of said compound in therapy, for instance in treating cognitive disorders, as well as to intermediates useful in the preparation thereof.Type: GrantFiled: December 19, 2011Date of Patent: April 21, 2015Assignee: AstraZeneca ABInventors: Helena Gybäck, Jonas Malmström, Elgaard Gitte Terp
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Patent number: 8957215Abstract: The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses for such compounds, having the structural formula (I) below: and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzothiazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.Type: GrantFiled: April 23, 2012Date of Patent: February 17, 2015Assignee: Navidea Biopharmaceuticals, Inc.Inventors: Ylva Gravenfors, Catrin Jonasson, Jonas Malmstrom, Gunnar Nordvall, David Pyring, Can Slivo, Daniel Sohn, Peter Strom, David Wensbo
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Publication number: 20140329830Abstract: The present invention relates to a compound of formula (I), and to pharmaceutical compositions containing said compound and to the use of said compound in therapy, for instance in treating cognitive disorders, as well as to intermediates useful in the preparation thereof.Type: ApplicationFiled: December 19, 2011Publication date: November 6, 2014Applicant: AstraZeneca ABInventors: Helena Gybäck, Jonas Malmström, Elgaard Gitte Terp
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Patent number: 8859534Abstract: The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted; R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocyclyl, C1-4alkylheterocyclyl, heterocyclyl-heteroaryl, aryl-heterocyclyl, carbocyclyl-heteroaryl, heterocyclyl-aryl, optionally substituted; R3 is hydrogen or C1-4alkyl, or R2 and R3 may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms, and optionally substituted; R4 is hydrogen, halogen, methyl or methoxy; to pharmaceutical composition containing said compounds and to the use of said compounds in therapy, for instance in treating cognitive disorders. The present invention further relates to new intermediates useful in the preparation thereof.Type: GrantFiled: February 4, 2013Date of Patent: October 14, 2014Assignee: Acturum Life Science ABInventors: Johan Andersson, Helena Gyback, Anh Johansson, Christian Erik Linde, Jonas Malmstrom, Gunnar Nordvall, Tatjana Weigelt, Gitte Terp
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Patent number: 8367676Abstract: The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted; R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocyclyl, C1-4alkylheterocyclyl, heterocyclyl-heteroaryl, aryl-heterocyclyl, carbocyclyl-heteroaryl, heterocyclyl-aryl, optionally substituted; R3 is hydrogen or C1-4alkyl, or R2 and R3 may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms, and optionally substituted; R4 is hydrogen, halogen, methyl or methoxy; to pharmaceutical composition containing said compounds and to the use of said compounds in therapy, for instance in treating cognitive disorders. The present invention further relates to new intermediates useful in the preparation thereof.Type: GrantFiled: June 28, 2010Date of Patent: February 5, 2013Assignee: AstraZeneca ABInventors: Johan Andersson, Helena Gybäck, Anh Johansson, Christian Erik Linde, Jonas Malmström, Gunnar Nordvall, Tatjana Weigelt, Gitte Terp
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Publication number: 20120207679Abstract: The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses for such compounds, having the structural formula (I) below: and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzothiazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.Type: ApplicationFiled: April 23, 2012Publication date: August 16, 2012Applicant: ASTRAZENECA ABInventors: Ylva Gravenfors, Catrin Jonasson, Jonas Malmström, Gunnar Nordvall, David Pyring, Can Slivo, Daniel Sohn, Peter Ström, David Wensbo
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Patent number: 8163928Abstract: The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses for such compounds, having the structural formula (I) below: [Chemical formula should be inserted here. Please see paper copy] and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzothiazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.Type: GrantFiled: January 25, 2007Date of Patent: April 24, 2012Assignee: AstraZeneca ABInventors: Ylva Gravenfors, Catrin Jonasson, Jonas Malmstrom, Gunnar Nordvall, David Pyring, Can Slivo, Daniel Sohn, Peter Strom, David Wensbo
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Publication number: 20110098292Abstract: The present invention provides new compounds of formula (I) as well as a process for their preparation and new intermediates used therein, pharmaceutical formulations containing said therapeutically active compounds and to the use of said active compounds in therapy.Type: ApplicationFiled: June 29, 2005Publication date: April 28, 2011Applicant: AstraZeneca ABInventors: Jonas Malmstrom, Jenny Viklund
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Publication number: 20100331341Abstract: The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted; R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocyclyl, C1-4alkylheterocyclyl, heterocyclyl-heteroaryl, aryl-heterocyclyl, carbocyclyl-heteroaryl, heterocyclyl-aryl, optionally substituted; R3 is hydrogen or C1-4alkyl, or R2 and R3 may together with the nitrogen atom, form a saturated ring system containing 4, 5 or 6 ring forming atoms, and optionally substituted; R4 is hydrogen, halogen, methyl or methoxy; to pharmaceutical composition containing said compounds and to the use of said compounds in therapy, for instance in treating cognitive disorders. The present invention further relates to new intermediates useful in the preparation thereof.Type: ApplicationFiled: June 28, 2010Publication date: December 30, 2010Applicant: ASTRAZENECA ABInventors: Johan ANDERSSON, Helena GYBÄCK, Anh JOHANSSON, Christian Erik LINDE, Jonas MALMSTRÖM, Gunnar NORDVALL, Tatjana WEIGELT, Gitte TERP
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Publication number: 20100092385Abstract: The present invention relates to novel heteroaryl substituted imidazopyridine derivatives, precursors thereof, and therapeutic uses of such compounds, having the structural formula (Ia) and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted imidazopyridine derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.Type: ApplicationFiled: January 21, 2008Publication date: April 15, 2010Applicant: ASTRAZENECA ABInventors: Michaela Vallin, Jonas Malmstrom, David Pyring, Can Slivo, David Wensbo
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Patent number: 7670591Abstract: The present invention relates to novel heteroaryl substituted benzoxazole derivatives and therapeutic uses for such compounds, having the structural formula (Ia) below: and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzoxazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.Type: GrantFiled: June 14, 2007Date of Patent: March 2, 2010Assignee: AstraZeneca ABInventors: Jonas Malmstrom, David Pyring, Can Slivo, Daniel Sohn, Britt-Marie Swahn, David Wensbo
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Publication number: 20090028787Abstract: The present invention relates to novel heteroaryl substituted benzothiazole derivatives, precursors thereof, and therapeutic uses for such compounds, having the structural formula (I) below: [Chemical formula should be inserted here. Please see paper copy] and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzothiazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents.Type: ApplicationFiled: January 25, 2007Publication date: January 29, 2009Inventors: Ylva Gravenfors, Catrin Jonasson, Jonas Malmstrom, Gunnar Nordvall, David Pyring, Can Slivo, Daniel Sohn, Peter Strom, David Wensbo
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Publication number: 20080251120Abstract: The present invention relates to a thin film solar cell and a method of manufacturing such cells. In particular the invention relates to the use of a composite back contact (314) in Cu(In,Ga)Se2 (CIGS) based thin film solar cells with thin absorber layers. The composite back contact (314) is provided between the substrate (105) and the absorber (115) and comprises: a back reflector layer (311) that enhance the reflectance at the absorber/composite back contact interface; and at least a contact layer that contact layer (310, 313) that ensures suitable electrical properties of the back contact with respect to the absorber; and/or a conductance layer (312) that ensures low sheet resistance for the in-plane current flow.Type: ApplicationFiled: March 3, 2005Publication date: October 16, 2008Applicant: SOLIBRO ABInventors: Jonas Malmstrom, Lars Stolt
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Publication number: 20080027051Abstract: The present invention relates to novel heteroaryl substituted benzoxazole derivatives and therapeutic uses for such compounds, having the structural formula (Ia) below: and to their pharmaceutically acceptable salt, compositions and methods of use. Furthermore, the invention relates to novel heteroaryl substituted benzoxazole derivatives that are suitable for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. More specifically, the present invention relates to a method of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease as well as measureing clinical efficacy of Alzheimer's disease therapeutic agents.Type: ApplicationFiled: June 14, 2007Publication date: January 31, 2008Applicant: AstraZeneca ABInventors: Jonas Malmstrom, David Pyring, Can Slivo, Daniel Sohn, Britt-Marie Swahn, David Wensbo
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Patent number: 6937844Abstract: The present invention relates to a arrangement and method for providing wireless communication between GPIB devices and a host computer. An GPIB adapter (100) according to the present invention provides wireless communication between a GPIB device (200) and a computer (120), the adapter comprises a command handle (140)r adapted for communication with a wireless communication module (130). The adapter further comprises a GPIB control unit (150) and the command handler is adapted for executing GPIB function calls directed to a GPIB device through the GPIB control unit (150). The command handler comprises a GPIB driver (344) which is adapted for communication with the GPIB control unit (150). The arrangement makes it possible for the adapter to provide complete GPIB functionality.Type: GrantFiled: May 30, 2002Date of Patent: August 30, 2005Assignee: Wireless Lab Sweden ABInventors: Jonas Malmstrom, Johan Wennerberg, Marcus Jonsson
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Publication number: 20050113370Abstract: The invention provides a compound of Formula I Formula I wherein R1 is aryl or heteroaryl each of which is optionally substituted with one or more of the following R3, —OR3, —OCOR3, —COOR3, —COR3, —CONR3R4, —NHCOR3, —NR3R4, —NHSO2R3, —S2R3, —SO2NR3R4, —SR3, CN, halogeno or NO2; R2 is NO2, NH2, —NR5R6 or —NR6R7; as a free base or a pharmaceutically acceptable salt, solvate or solvate of salt thereof, a process for their preparation, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.Type: ApplicationFiled: February 11, 2003Publication date: May 26, 2005Inventors: Jonas Malmstrom, Britt-Marie Swahn
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Publication number: 20040198219Abstract: The present invention relates to a arrangement and method for providing wireless communication between GPIB devices and a host computer. An GPIB adapter (100) according to the present invention provides wireless communication between a GPIB device (200) and a computer (120), the adapter comprises a command handle (140)r adapted for communication with a wireless communication module (130). The adapter further comprises a GPIB control unit (150) and the command handler is adapted for executing GPIB function calls directed to a GPIB device through the GPIB control unit (150). The command handler comprises a GPIB driver (344) which is adapted for communication with the GPIB control unit (150). The arrangement makes it possible for the adapter to provide complete GPIB functionality.Type: ApplicationFiled: May 30, 2002Publication date: October 7, 2004Inventors: Jonas Malmstrom, Johan Wennerberg, Marcus Jonsson