Abstract: Methods for preserving catalytic activity of a PSA polymer membrane in a humid environment by immobilizing in the membrane an organic acid having a pKa greater than the pKa of the PSA polymer membrane; optical sensors based on the PSA membranes further including an immobilized organic reagent capable of reacting with a target compound in a humid environment to produce a detectable color shifted product; and non-invasive methods for estimating blood glucose concentration by utilizing an optical sensor to detect concentration of acetone in exhaled human breath and correlating it to blood glucose concentration.

Abstract: Various embodiments include methods and scanning systems for photonically detecting an object of high-interest having selective wavelength reflection. Various embodiments include sequentially scanning the environment by projecting a non-coherent pulsed electromagnetic beam of light of a first wavelength. Reflected light of the first non-coherent beam is received onto a photoelectric detector, which outputs digital intensity data. Various embodiments further include sequentially scanning the environment by projecting a non-coherent pulsed electromagnetic beam of light of a second wavelength different from the first wavelength. Reflected light of the second non-coherent beam is received onto a photoelectric detector, which outputs digital intensity data. The intensity of the reflected light of the first wavelength may be compared with the intensity reflected light of the second wavelength, and an alert may be sent to an autonomous vehicle system in response to the intensity difference exceeding a threshold.

Abstract: Various embodiments include methods and scanning systems for photonically detecting an object of high-interest having selective wavelength reflection. Various embodiments include sequentially scanning the environment by projecting a coherent pulsed electromagnetic beam of light of a first wavelength. Reflected light of the first coherent beam is received onto a photoelectric detector, which outputs digital intensity data. Various embodiments further include sequentially scanning the environment by projecting a coherent pulsed electromagnetic beam of light of a second wavelength different from the first wavelength. Reflected light of the second coherent beam is received onto a photoelectric detector, which outputs digital intensity data. The intensity of the reflected light of the first wavelength may be compared with the intensity reflected light of the second wavelength, and an alert may be sent to an autonomous vehicle system in response to the intensity difference exceeding a threshold.

Abstract: Provided herein is a method of diagnosing and treating a subject suffering from atopic dermatitis (AD), the method comprising: (a) obtaining a skin biopsy from a subject suspected of suffering from AD; (b) determining a level of RNA expression in the skin biopsy of genes selected from the 89ADGES gene panel; (c) comparing the determined level of RNA expression of the selected genes to the level of RNA expression of the selected genes in a reference sample comprising RNA expression products from normal healthy skin cells; (d) diagnosing the subject as suffering from AD when specific genes are up-regulated compared to the reference sample and when specific genes are down-regulated compared to the reference sample; and (e) treating the subject with a therapy effective for the treatment of AD. Methods of managing treatment of a subject suffering from AD are also provided.

Abstract: This disclosure provides systems and methods for delivering a neural stimulation pulse. A neural implant device can include an energy harvesting circuit configured to receive an input signal and generate an electrical signal based on the received input signal. A diode rectifier in series with the energy harvesting circuit can rectify the electrical signal. The energy harvesting circuit and the diode rectifier can be encapsulated within a biocompatible electrically insulating material. A neural electrode can be exposed through the biocompatible electrically insulating material. The neural electrode can be configured to deliver a neural stimulation pulse. The neural implant device can have a volume that is less than about 1.0 cubic millimeter.

Abstract: Electromechanical device structures are provided, as well as methods for forming them. The device structures incorporate at least a first and second substrate separated by an interface material layer, where the first substrate comprises an anchor material structure and at least one suspended material structure, optionally a spring material structure, and optionally an electrostatic sense electrode. The device structures may be formed by methods that include providing an interface material layer on one or both of the first and second substrates, bonding the interface materials to the opposing first or second substrate or to the other interface material layer, followed by forming the suspended material structure by etching.

Abstract: Electromechanical device structures are provided, as well as methods for forming them. The device structures incorporate at least a first and second substrate separated by an interface material layer, where the first substrate comprises an anchor material structure and at least one suspended material structure, optionally a spring material structure, and optionally an electrostatic sense electrode. The device structures may be formed by methods that include providing an interface material layer on one or both of the first and second substrates, bonding the interface materials to the opposing first or second substrate or to the other interface material layer, followed by forming the suspended material structure by etching.

Abstract: Electromechanical device structures are provided, as well as methods for forming them. The device structures incorporate at least a first and second substrate separated by an interface material layer, where the first substrate comprises an anchor material structure and at least one suspended material structure, optionally a spring material structure, and optionally an electrostatic sense electrode. The device structures may be formed by methods that include providing an interface material layer on one or both of the first and second substrates, bonding the interface materials to the opposing first or second substrate or to the other interface material layer, followed by forming the suspended material structure by etching.

Abstract: An item of clothing in the form of a jacket provides enhanced visibility for a cyclist. A right detection device is configured to identify a raising of a right arm and a right indictor light (103) is configured to indicate in response to the raising of the right arm. Similarly, a left detection device is configured to identify the raising of a left arm and a left indicator light 104 is configured to indicate in response to the raising of the left arm. A housing contains a power supply and a control circuit and a pocket is provided in the jacket for supporting the housing. Wires extend from the housing to the detection devices and indicators and these wires are restrained within seams used to construct the jacket.

Abstract: A jacket 101 has a detector, such as a gas detector, for detecting an environmental hazard. The jacket has a first warning device for issuing a first warning in response to detecting the environmental hazard. Furthermore, the jacket is provided with a transmission device for transmitting a warning signal to similar jackets worn by operatives within the environment. Each jacket includes a second warning device for issuing a second warning in response to receiving a warning signal from any other jackets or clothing.

Abstract: Various embodiments include methods and scanning systems for photonically detecting an object of high-interest having selective wavelength reflection. Various embodiments include sequentially scanning the environment by projecting a coherent pulsed electromagnetic beam of light of a first wavelength. Reflected light of the first coherent beam is received onto a photoelectric detector, which outputs digital intensity data. Various embodiments further include sequentially scanning the environment by projecting a coherent pulsed electromagnetic beam of light of a second wavelength different from the first wavelength. Reflected light of the second coherent beam is received onto a photoelectric detector, which outputs digital intensity data. The intensity of the reflected light of the first wavelength may be compared with the intensity reflected light of the second wavelength, and an alert may be sent to an autonomous vehicle system in response to the intensity difference exceeding a threshold.

Abstract: Provided herein is a method of diagnosing and treating a subject suffering from atopic dermatitis (AD), the method comprising: (a) obtaining a skin biopsy from a subject suspected of suffering from AD; (b) determining a level of RNA expression in the skin biopsy of genes selected from the 89ADGES gene panel; (c) comparing the determined level of RNA expression of the selected genes to the level of RNA expression of the selected genes in a reference sample comprising RNA expression products from normal healthy skin cells; (d) diagnosing the subject as suffering from AD when specific genes are up-regulated compared to the reference sample and when specific genes are down-regulated compared to the reference sample; and (e) treating the subject with a therapy effective for the treatment of AD. Methods of managing treatment of a subject suffering from AD are also provided.

Abstract: A control module (105) is supported within an item of clothing. The control module is located within a pocket (503). A visual indicator (1201) is pressed on the jacket at a position in front of the activation button on the control module. The activation button has a surface area that covers at least 40% of a surface area of the control module. In this way, it is possible for the control module to move within the pocket while still facilitating activation and deactivation upon pressing the visual indicator.

Abstract: This disclosure provides systems and methods for delivering a neural stimulation pulse. A neural implant device can include an energy harvesting circuit configured to receive an input signal and generate an electrical signal based on the received input signal. A diode rectifier in series with the energy harvesting circuit can rectify the electrical signal. The energy harvesting circuit and the diode rectifier can be encapsulated within a biocompatible electrically insulating material. A neural electrode can be exposed through the biocompatible electrically insulating material. The neural electrode can be configured to deliver a neural stimulation pulse. The neural implant device can have a volume that is less than about 1.0 cubic millimeter.

Abstract: A jacket 101 has a detector, such as a gas detector, for detecting an environmental hazard. The jacket has a first warning device for issuing a first warning in response to detecting the environmental hazard. Furthermore, the jacket is provided with a transmission device for transmitting a warning signal to similar jackets worn by operatives within the environment. Each jacket includes a second warning device for issuing a second warning in response to receiving a warning signal from any other jackets or clothing.

Abstract: Electromechanical device structures are provided, as well as methods for forming them. The device structures incorporate at least a first and second substrate separated by an interface material layer, where the first substrate comprises an anchor material structure and at least one suspended material structure, optionally a spring material structure, and optionally an electrostatic sense electrode. The device structures may be formed by methods that include providing an interface material layer on one or both of the first and second substrates, bonding the interface materials to the opposing first or second substrate or to the other interface material layer, followed by forming the suspended material structure by etching.

Abstract: An optical sensor for monitoring an environmental condition, the optical sensor comprising a perfluorosulfonate ionomer membrane comprising a solution, wherein the solution comprises a transition metal-free dye component, wherein exposure of the optical sensor to a specific environmental condition produces a color shift on the optical sensor.