Patents by Inventor Jonathan A. Coe

Jonathan A. Coe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11596439
    Abstract: A surgical access device and methods for facilitating access through an incision or wound to a surgical site in a patient's body comprising an inferior retention member, a superior retention member, and a pliable membrane therebetween. The pliable membrane includes a base layer, a permeable membrane attached to the base layer, and a fluid delivery region disposed between the layers. The fluid delivery region is fluidly coupled to a fluid source. The fluid is delivered to the surgical site via the permeable membrane. The inferior retention member provides for fluid removal from the surgical site. Methods are provided for use of the surgical access device to retract tissue and deliver fluid to the tissue from the pliable membrane.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: March 7, 2023
    Assignee: Prescient Surgical, Inc.
    Inventors: Jonathan Coe, Jeremy Koehler, Nicholas Spinelli, Edward Ruppel, III, Kevin McDermott
  • Publication number: 20220409600
    Abstract: The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.
    Type: Application
    Filed: May 24, 2022
    Publication date: December 29, 2022
    Inventors: Celia Dominguez, Jonathan Bard, Matthew R. Lee, Longbin Liu, Michael Edward Prime, Samuel Coe
  • Patent number: 11389438
    Abstract: The present disclosure relates generally to compounds that simultaneously bind both mutant huntingtin protein (mHTT) and an ubiquitin E3 ligase and their use as therapeutic agents, for example, in treating diseases, such as neurodegenerative disorders caused by aggregation of mHTT.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: July 19, 2022
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Jonathan Bard, Matthew R. Lee, Longbin Liu, Michael Edward Prime, Samuel Coe
  • Patent number: 10993709
    Abstract: A surgical access system facilitates access to a surgical site within a patient's body through an incision in the body. Surgical access systems can have at least one retention member and a fluid transportation member configured to deliver fluid to a surgical site or to remove fluid from a surgical site. In some embodiments, a surgical access device irrigates a surgical site to reduce surgical site infections and removes fluid from the surgical site to increase a physician's visibility into the surgical site.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: May 4, 2021
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Insoo Suh, Jonathan Coe, Swaminadhan Gnanashanmugam, Jeremy Koehler, Mark Welton
  • Publication number: 20210000501
    Abstract: A surgical access device and methods for facilitating access through an incision or wound to a surgical site in a patient's body comprising an inferior retention member, a superior retention member, and a pliable membrane therebetween. The pliable membrane includes a base layer, a permeable membrane attached to the base layer, and a fluid delivery region disposed between the layers. The fluid delivery region is fluidly coupled to a fluid source. The fluid is delivered to the surgical site via the permeable membrane. The inferior retention member provides for fluid removal from the surgical site. Methods are provided for use of the surgical access device to retract tissue and deliver fluid to the tissue from the pliable membrane.
    Type: Application
    Filed: May 7, 2020
    Publication date: January 7, 2021
    Inventors: Jonathan Coe, Jeremy Koehler, Nicholas Spinelli, Edward Ruppel, III, Kevin McDermott
  • Patent number: 10709496
    Abstract: A forceps includes an end effector assembly including first and second jaw members. One or both of the jaw members is movable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One or both of the jaw members is configured to conduct energy between the jaw members and through tissue grasped therebetween to treat tissue. An insulative tubular member is movable relative to the end effector assembly between a retracted position, wherein the insulative tubular member is positioned proximally of the end effector assembly, and an extended position, wherein the insulative tubular member is disposed about the end effector assembly. A monopolar member is configured to apply energy to tissue to treat tissue when the insulative tubular member is disposed in the extended position.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: July 14, 2020
    Assignee: Covidien LP
    Inventors: Tony Moua, David N. Heard, Jonathan A. Coe, John J. Kappus, Peter M. Mueller, Raymond A. Sirianne, Ryan C. Artale
  • Publication number: 20190231335
    Abstract: A surgical access system facilitates access to a surgical site within a patient's body through an incision in the body. Surgical access systems can have at least one retention member and a fluid transportation member configured to deliver fluid to a surgical site or to remove fluid from a surgical site. In some embodiments, a surgical access device irrigates a surgical site to reduce surgical site infections and removes fluid from the surgical site to increase a physician's visibility into the surgical site.
    Type: Application
    Filed: September 4, 2018
    Publication date: August 1, 2019
    Inventors: Insoo Suh, Jonathan Coe, Swaminadhan Gnanashanmugam, Jeremy Koehler, Mark Welton
  • Patent number: 10327751
    Abstract: A surgical access system that facilitates access to a surgical site through an incision in the patient's body includes a surgical retractor and a fluid delivery or fluid evacuation device. The fluid delivery or fluid evacuation device is coupled to the surgical retractor and is adapted to deliver fluid to the surgical site or evacuate fluid from the surgical site.
    Type: Grant
    Filed: March 20, 2014
    Date of Patent: June 25, 2019
    Assignee: Prescient Surgical, Inc.
    Inventors: Jonathan Coe, Insoo Suh, Jeremy Koehler
  • Publication number: 20190090902
    Abstract: A surgical access device for facilitating access through an incision to a surgical site in a patient's body has a pliable membrane which is configured to engage and expand the incision. The pliable membrane includes a base layer, a permeable membrane attached to the base layer, and a fluid channel disposed between the layers. The fluid channel is fluidly coupled to a fluid source. The fluid is delivered to the surgical site via the permeable membrane. The surgical access device may also have a locking mechanism for holding the device in a desired configuration.
    Type: Application
    Filed: April 19, 2018
    Publication date: March 28, 2019
    Inventors: Jeremy KOEHLER, Jonathan COE, Insoo SUH
  • Patent number: 10194931
    Abstract: Methods and devices are provided for performing various procedures using interchangeable end effectors. In general, the methods and devices allow a surgeon to remotely and selectively attach various interchangeable surgical end effectors to a shaft located within a patient's body, thus allowing the surgeon to perform various procedures without the need to remove the shaft from the patient's body. In an exemplary embodiment, multiple end effectors can be introduced into a body cavity. The end effectors can be disassociated or separate from one another such that they float within the body cavity. A distal end of a shaft can be positioned within the body cavity and it can be used to selectively engage one of the end effectors. In particular, the device can be configured to allow each end effector to be remotely attached and detached from the distal end of the shaft.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: February 5, 2019
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: Jonathan A. Coe, James W. Voegele, Gary L. Long, Andrew M. Zwolinski, Kyle P. Moore, Robert P. Gill
  • Patent number: 10085734
    Abstract: A surgical access system facilitates access to a surgical site within a patient's body through an incision in the body. Surgical access systems can have at least one retention member and a fluid transportation member configured to deliver fluid to a surgical site or to remove fluid from a surgical site. In some embodiments, a surgical access device irrigates a surgical site to reduce surgical site infections and removes fluid from the surgical site to increase a physician's visibility into the surgical site.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: October 2, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Insoo Suh, Jonathan Coe, Swaminadhan Gnanashanmugam, Jeremy Koehler, Mark Welton
  • Publication number: 20180206906
    Abstract: A forceps includes an end effector assembly including first and second jaw members. One or both of the jaw members is movable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One or both of the jaw members is configured to conduct energy between the jaw members and through tissue grasped therebetween to treat tissue. An insulative tubular member is movable relative to the end effector assembly between a retracted position, wherein the insulative tubular member is positioned proximally of the end effector assembly, and an extended position, wherein the insulative tubular member is disposed about the end effector assembly. A monopolar member is configured to apply energy to tissue to treat tissue when the insulative tubular member is disposed in the extended position.
    Type: Application
    Filed: March 19, 2018
    Publication date: July 26, 2018
    Inventors: TONY MOUA, DAVID N. HEARD, JONATHAN A. COE, JOHN J. KAPPUS, PETER M. MUELLER, RAYMOND A. SIRIANNE, RYAN C. ARTALE
  • Patent number: 9974564
    Abstract: A surgical access device for facilitating access through an incision to a surgical site in a patient's body has a pliable membrane which is configured to engage and expand the incision. The pliable membrane includes a base layer, a permeable membrane attached to the base layer, and a fluid channel disposed between the layers. The fluid channel is fluidly coupled to a fluid source. The fluid is delivered to the surgical site via the permeable membrane. The surgical access device may also have a locking mechanism for holding the device in a desired configuration.
    Type: Grant
    Filed: February 24, 2017
    Date of Patent: May 22, 2018
    Assignee: Prescient Surgical, Inc.
    Inventors: Jeremy Koehler, Jonathan Coe, Insoo Suh
  • Patent number: 9918784
    Abstract: A forceps includes an end effector assembly including first and second jaw members. One or both of the jaw members is movable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One or both of the jaw members is configured to conduct energy between the jaw members and through tissue grasped therebetween to treat tissue. An insulative tubular member is movable relative to the end effector assembly between a retracted position, wherein the insulative tubular member is positioned proximally of the end effector assembly, and an extended position, wherein the insulative tubular member is disposed about the end effector assembly. A monopolar member is configured to apply energy to tissue to treat tissue when the insulative tubular member is disposed in the extended position.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: March 20, 2018
    Assignee: COVIDIEN LP
    Inventors: Tony Moua, David N. Heard, Jonathan A. Coe, John J. Kappus, Peter M. Mueller, Raymond A. Sirianne, Ryan C. Artale
  • Patent number: 9833623
    Abstract: A method is described for decreasing activity of at least one sympathetic nerve, nerve fiber or neuron innervating at least one blood vessel in the pulmonary vasculature of a patient to ameliorate pulmonary hypertension. In one embodiment, the method may involve advancing an intravascular treatment device to a target location in a target blood vessel within the pulmonary vasculature of the patient and using the treatment device to decrease activity of at least one sympathetic nerve, nerve fiber or neuron innervating the target blood vessel at or near the target location to ameliorate pulmonary hypertension.
    Type: Grant
    Filed: April 13, 2015
    Date of Patent: December 5, 2017
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Swaminadhan Gnanashanmugam, Jonathan A. Coe, Insoo Suh, Jeremy Christopher Koehler
  • Patent number: 9788823
    Abstract: Several methods to reduce surgical site infections include inserting a surgical access device into an incision, retracting tissue, and introducing fluid into the surgical access device such that the fluid exits the surgical access device and irrigates a surgical site. Other methods do not include introducing fluid into a surgical access device but include suctioning a fluid into the surgical access device and removing the fluid from the body.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: October 17, 2017
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Insoo Suh, Jonathan Coe, Swaminadhan Gnanashanmugam, Jeremy Koehler, Mark Welton
  • Publication number: 20170281147
    Abstract: A surgical access device for facilitating access through an incision to a surgical site in a patient's body has a pliable membrane which is configured to engage and expand the incision. The pliable membrane includes a base layer, a permeable membrane attached to the base layer, and a fluid channel disposed between the layers. The fluid channel is fluidly coupled to a fluid source. The fluid is delivered to the surgical site via the permeable membrane. The surgical access device may also have a locking mechanism for holding the device in a desired configuration.
    Type: Application
    Filed: February 24, 2017
    Publication date: October 5, 2017
    Inventors: Jeremy Koehler, Jonathan Coe, Insoo Suh
  • Publication number: 20170258483
    Abstract: Methods and devices are provided for performing various procedures using interchangeable end effectors. In general, the methods and devices allow a surgeon to remotely and selectively attach various interchangeable surgical end effectors to a shaft located within a patient's body, thus allowing the surgeon to perform various procedures without the need to remove the shaft from the patient's body. In an exemplary embodiment, multiple end effectors can be introduced into a body cavity. The end effectors can be disassociated or separate from one another such that they float within the body cavity. A distal end of a shaft can be positioned within the body cavity and it can be used to selectively engage one of the end effectors. In particular, the device can be configured to allow each end effector to be remotely attached and detached from the distal end of the shaft.
    Type: Application
    Filed: May 25, 2017
    Publication date: September 14, 2017
    Inventors: Jonathan A. Coe, James W. Voegele, Gary L. Long, Andrew M. Zwolinski, Kyle P. Moore, Robert P. Gill
  • Publication number: 20170238992
    Abstract: A forceps includes an end effector assembly including first and second jaw members. One or both of the jaw members is movable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One or both of the jaw members is configured to conduct energy between the jaw members and through tissue grasped therebetween to treat tissue. An insulative tubular member is movable relative to the end effector assembly between a retracted position, wherein the insulative tubular member is positioned proximally of the end effector assembly, and an extended position, wherein the insulative tubular member is disposed about the end effector assembly. A monopolar member is configured to apply energy to tissue to treat tissue when the insulative tubular member is disposed in the extended position.
    Type: Application
    Filed: May 10, 2017
    Publication date: August 24, 2017
    Inventors: TONY MOUA, DAVID N. HEARD, JONATHAN A. COE, JOHN J. KAPPUS, PETER M. MUELLER, RAYMOND A. SIRIANNE, RYAN C. ARTALE
  • Patent number: 9662132
    Abstract: Methods and devices are provided for performing various procedures using interchangeable end effectors. In general, the methods and devices allow a surgeon to remotely and selectively attach various interchangeable surgical end effectors to a shaft located within a patient's body, thus allowing the surgeon to perform various procedures without the need to remove the shaft from the patient's body. In an exemplary embodiment, multiple end effectors can be introduced into a body cavity. The end effectors can be disassociated or separate from one another such that they float within the body cavity. A distal end of a shaft can be positioned within the body cavity and it can be used to selectively engage one of the end effectors. In particular, the device can be configured to allow each end effector to be remotely attached and detached from the distal end of the shaft.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: May 30, 2017
    Assignee: Ethicon Endo-Surgery, Inc.
    Inventors: Jonathan A. Coe, James W. Voegele, Gary L. Long, Andrew M. Zwolinski, Kyle P. Moore, Robert P. Gill