Abstract: The invention concerns an antidegradant blend, comprising: an aminic component comprising a hydroxylamine and/or a hydroxylamine precursor; and an inorganic antioxidant or reducing agent.

Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.

Abstract: Antibody molecules that bind to CD73 are disclosed. The anti-CD73 antibody molecules can be used to treat, prevent and/or diagnose cancer.

Abstract: The present invention relates to stabilising compositions, particularly stabilising compositions which can be used to stabilise elastomeric materials, such as rubbers and/or butadiene based elastomers. The stabilising composition comprises: a first stabilising component comprising at least one phosphite antioxidant; a second stabilising component comprising at least one aminic antioxidant; and a third stabilising component comprising at least one phenolic antioxidant. Also disclosed herein is use of the stabilising composition for stabilising elastomeric materials, a stabilised composition comprising an elastomeric material and the aforementioned stabilising composition and a useful article comprising the stabilising composition.

Abstract: The present invention provides a stabilising composition, comprising: a) a first phenolic antioxidant comprising one or more phenolic compounds having the structure of formula (I): ?wherein R1 is a linear or branched alkyl group having from 12 to 20 carbon atoms; and b) one or more second phenolic antioxidants independently selected from: ?a mono-hydroxybenzene having lower steric hindrance than the first ?phenolic antioxidant; ?a di-hydroxybenzene; and/or ?a tri-hydroxybenzene.

Abstract: The present invention provides a stabilising composition, comprising: a) a first phenolic antioxidant comprising one or more phenolic compounds having the structure of formula (I): ?wherein R1 is a linear or branched alkyl group having from 12 to 20 carbon atoms; and b) one or more second phenolic antioxidants independently selected from: ?a mono-hydroxybenzene having lower steric hindrance than the first phenolic antioxidant; ?a di-hydroxybenzene; and/or ?a tri-hydroxybenzene.

Abstract: The present invention provides a stabilising composition, comprising: a) a first phenolic antioxidant comprising one or more phenolic compounds having the structure of formula (I) wherein R1 is a linear or branched alkyl group having from 12 to 20 carbon atoms; and b) one or more second phenolic antioxidants independently selected from: a mono-hydroxybenzene having lower steric hindrance than the first phenolic antioxidant; a di-hydroxybenzene; and/or a tri-hydroxybenzene.

Abstract: The present invention concerns a stabilising antioxidative composition comprising tris(2-t-butylphenyl) phosphite in the absence of tris(2,4-di-t-butylphenyl) phosphite.

Abstract: The invention concerns an antidegradant blend for polymers, comprising: a. an antioxidant selected from one or more of: i. a phenolic antioxidant; ii. an organic phosphite antioxidant; and: b. an inorganic antioxidant or reducing agent; wherein the composition is absent any metal carboxylate or buffering agent having the capacity to buffer in aqueous solution at a pH range from 4 to 8.

Abstract: Antibody molecules that bind to CD73 are disclosed. The anti-CD73 antibody molecules can be used to treat, prevent and/or diagnose cancer.

Abstract: A shingle and a method of hanging the shingle by a fastener driven by a nail gun. The shingle can be formed from slate or made of clay, ceramic, glass, or concrete. The shingle includes at least one aperture for a fastener. The aperture is spaced a predetermined distance from an upper end of the shingle.

Abstract: Techniques for managing an application token may include providing, by a first service provider application on a communication device to a first service provider computer, a first request for a first application token, receiving, by an account management application on the communication device from a token service computer in communication with the first service provider computer, the first application token, and storing the first application token in a token container in the account management application.

Abstract: The present disclosure relates to anti-IL-27 antibodies, and antigen-binding portions thereof. The disclosure also relates to methods for treating or ameliorating one or more symptoms of a disease, such as cancer, by administering the antibodies or antigen-binding portion thereof. The disclosure also relates to methods for detecting IL-27 in, for example, a subject or a sample.

Abstract: Techniques for managing an application token may include providing, by a first service provider application on a communication device to a first service provider computer, a first request for a first application token, receiving, by an account management application on the communication device from a token service computer in communication with the first service provider computer, the first application token, and storing the first application token in a token container in the account management application.

Abstract: The present invention relates to a precursor material for an insulation composition, comprising: a crosslinkable graft polymer comprising a polyolefin component and a polyene component; and an antioxidant. The present invention also relates to an insulation composition obtained from the precursor material.

Abstract: Disclosed herein are anti-CD47 antibody molecules, their manufacture and use in treating disorders associated with CD47 expression, for example, certain hematological cancers and solid tumors.

Abstract: In accordance with the present invention there is provided an antidegradant blend, comprising: a metal carboxylate; an inorganic phosphite; and a phenolic antioxidant.

Abstract: A load bearing flexible conduit system (10) for use in a body of water and adapted for deployment from a reel (100) located on a water going vessel into the body of water is disclosed. The system comprises a number of lengths (12) of load bearing flexible conduit, each length of load bearing flexible conduit provided with an inner layer (44) having a throughbore and a load bearing outer layer (50). A joint (30) for connecting the lengths together has a body having a longitudinal axis and a throughbore and at least one flexible coupling to permit at least one of the said one ends of the respective first and second lengths of load bearing flexible conduit to move relative to the longitudinal axis of the joint. The lengths of load bearing flexible conduit are sufficiently flexible such that they are capable of being stored, prior to use, on a reel (100) and are further capable of being at least partially payed out from the reel into the body of water during use.

Abstract: The invention concerns a stabilising composition, comprising: at least one antioxidant comprising one or more of: a phenolic antioxidant, a phosphite antioxidant, a sulphur-containing antioxidant, and an aminic antioxidant; and at least one buffering agent, wherein the buffering agent has the capacity to buffer in aqueous solution at a pH range from 4 to 8.

Abstract: Disclosed herein are anti-CD47 antibody molecules, their manufacture and use in treating disorders associated with CD47 expression, for example, certain hematological cancers and solid tumors.