Patents by Inventor Jonathan A. Hodges

Jonathan A. Hodges has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COLLAGEN MIMICS
    Publication number: 20230159622
    Abstract: Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n, where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By substituting a proline derivative at either the Xaa or Yaa position in the native collagen helix, the stability of the helix is increased due solely to steric effects relative to prior known collagen-related triple helices. Methods are also disclosed for making the novel collagen mimics.
    Type: Application
    Filed: June 30, 2022
    Publication date: May 25, 2023
    Inventors: Ronald T. Raines, Matthew D. Shoulders, Jonathan A. Hodges
  • Collagen mimics
    Patent number: 11390662
    Abstract: Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n, where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By substituting a proline derivative at either the Xaa or Yaa position in the native collagen helix, the stability of the helix is increased due solely to steric effects relative to prior known collagen-related triple helices. Methods are also disclosed for making the novel collagen mimics.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: July 19, 2022
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Ronald T. Raines, Matthew D. Shoulders, Jonathan A. Hodges
  • COLLAGEN MIMICS
    Publication number: 20200024328
    Abstract: Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n, where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By substituting a proline derivative at either the Xaa or Yaa position in the native collagen helix, the stability of the helix is increased due solely to steric effects relative to prior known collagen-related triple helices. Methods are also disclosed for making the novel collagen mimics.
    Type: Application
    Filed: June 21, 2019
    Publication date: January 23, 2020
    Inventors: Ronald T. Raines, Matthew D. Shoulders, Jonathan A. Hodges
  • Collagen mimics
    Patent number: 10329341
    Abstract: Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n,where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By substituting a proline derivative at either the Xaa or Yaa position in the native collagen helix, the stability of the helix is increased due solely to steric effects relative to prior known collagen-related triple helices. Methods are also disclosed for making the novel collagen mimics.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: June 25, 2019
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ronald T. Raines, Matthew D. Shoulders, Jonathan A. Hodges
  • COLLAGEN MIMICS
    Publication number: 20180030115
    Abstract: Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n, where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By substituting a proline derivative at either the Xaa or Yaa position in the native collagen helix, the stability of the helix is increased due solely to steric effects relative to prior known collagen-related triple helices. Methods are also disclosed for making the novel collagen mimics.
    Type: Application
    Filed: August 2, 2017
    Publication date: February 1, 2018
    Inventors: Ronald T. Raines, Matthew D. Shoulders, Jonathan A. Hodges
  • Collagen mimics
    Patent number: 9758569
    Abstract: Novel collagen mimics are disclosed with a tripeptide unit having the formula (Xaa-Yaa-Gly)n, where one of the positions Xaa or Yaa is a bulky, non-electron withdrawing proline derivative. By substituting a proline derivative at either the Xaa or Yaa position in the native collagen helix, the stability of the helix is increased due solely to steric effects relative to prior known collagen-related triple helices. Methods are also disclosed for making the novel collagen mimics.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: September 12, 2017
    Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Ronald T. Raines, Matthew D. Shoulders, Jonathan A. Hodges
  • Collagen mimics
    Patent number: 7122521
    Abstract: A novel collagen mimic comprising a tripeptide unit having the formula (flpYaaGly)n, where flp is 4(S)-fluoro-L-proline, is disclosed. The collagen mimic has increased stability relative to the collagen-related triple helices (ProYaaGly)n, (hypYaaGly)n, and (HypYaaGly)n.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: October 17, 2006
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ronald T. Raines, Jonathan A. Hodges