Patents by Inventor Jonathan A. Kelber

Jonathan A. Kelber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for the Treatment and Prevention of Cancer
    Publication number: 20190216751
    Abstract: A method of treating a subject with cancer is provided. The method includes administering to a subject in need thereof an effective amount of a pharmaceutical composition that includes inhibitors of HDAC6 and/or sirtuins and an inhibitor of deoxyhypusine synthase (DHPS). Methods also include treating a subject with cancer by administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising at least one inhibitor of sirtuin and at least one inhibitor of histone deacetylase six (HDAC6); at least one inhibitor of sirtuin or at least one inhibitor of histone deacetylase six (HDAC6), or a combination thereof.
    Type: Application
    Filed: November 13, 2018
    Publication date: July 18, 2019
    Applicant: California State University Northridge
    Inventors: Jonathan A Kelber, Yvess Adamian, Lindsay Kutscher, Robert Guth, Cameron Geller
  • COMPOSITIONS AND METHODS FOR THE INHIBITION OF CRIPTO / GRP78 COMPLEX FORMATION AND SIGNALING
    Publication number: 20100135904
    Abstract: The present invention provides methods compositions and methods for treating a hyperproliferative disease comprising disrupting Cripto/GRP78 complex formation in a hyperproliferative cell. In certain embodiments, an antibody and/or siRNA may be used to inhibit Cripto/GRP78 binding, optionally coupled with other cancer therapies. Also provided are methods for identifying therapeutic compounds which can selectively inhibit Cripto/GRP78 binding.
    Type: Application
    Filed: November 9, 2009
    Publication date: June 3, 2010
    Applicant: RESEARCH DEVELOPMENT FOUNDATION
    Inventors: Peter C. Gray, Gidi Shani, Jonathan A. Kelber, Wylie Vale