Patents by Inventor Jonathan A. Mills
Jonathan A. Mills has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140038840Abstract: The present invention provides a method of identifying one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia, the method comprising a) obtaining a first group of samples comprising genomic DNA from a plurality of bipolar or schizophrenic subjects and a second group of samples comprising genomic DNA from a plurality of control subjects; b) performing DNA methylation analysis to determine methylation differences in one or more DNA regions between the first group and second group of samples, wherein a methylation difference in a DNA region is indicative of an epigenetic marker associated with bipolar disease or schizophrenia. The invention also provides one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia.Type: ApplicationFiled: August 2, 2013Publication date: February 6, 2014Applicant: CENTRE FOR ADDICTION AND MENTAL HEALTHInventors: Arturas PETRONIS, Jonathan MILL, James FLANAGAN, Sun-Chong WANG
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Publication number: 20130159008Abstract: Embodiments of the invention provide systems and method for verifying healthcare visits. Location verification information may be received from a portable device by a verification system that includes one or more computers. The portable device may be associated with an individual directed to provide a healthcare service to a patient during a healthcare visit, and the location verification information may be collected by the portable device. The verification system may compare at least a portion of the received information to stored information associated with the patient. Based at least in part upon the comparison, the verification system may determine whether the healthcare visit was performed at an approved service location for the patient.Type: ApplicationFiled: December 20, 2011Publication date: June 20, 2013Applicant: FIRST DATA CORPORATIONInventors: Jonathan Mills, Thomas M. Rempe, Chuck Eliasen, Anish Bole, Robyn M. Andersen, Valerie Stribbling
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Patent number: 8337824Abstract: The present invention is directed to compositions of a linear polyol and a salt of a crosslinked cation exchange polymer comprising a fluoro group and an acid group. These compositions are useful to bind potassium in the gastrointestinal tract.Type: GrantFiled: August 22, 2009Date of Patent: December 25, 2012Assignee: Relypsa, Inc.Inventors: Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Ramakrishnan Chidambaram, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Jonathan Mills, Werner Strüver
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Publication number: 20120220475Abstract: The present invention provides a method of identifying one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia, the method comprising a) obtaining a first group of samples comprising genomic DNA from a plurality of bipolar or schizophrenic subjects and a second group of samples comprising genomic DNA from a plurality of control subjects; b) performing DNA methylation analysis to determine methylation differences in one or more DNA regions between the first group and second group of samples, wherein a methylation difference in a DNA region is indicative of an epigenetic marker associated with bipolar disease or schizophrenia. The invention also provides one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia.Type: ApplicationFiled: December 27, 2011Publication date: August 30, 2012Applicant: CENTRE FOR ADDICTION AND MENTAL HEALTHInventors: Arturas PETRONIS, Jonathan MILL, James FLANAGAN, Sun-Chong WANG
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Publication number: 20110236340Abstract: The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.Type: ApplicationFiled: August 22, 2009Publication date: September 29, 2011Applicant: Relypsa, Inc.Inventors: Paul Mansky, Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Ramakrishnan Chidambaram, Jonathan Mills, Werner Strüver
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Publication number: 20100234242Abstract: The present invention provides a method of identifying one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia, the method comprising a) obtaining a first group of samples comprising genomic DNA from a plurality of bipolar or schizophrenic subjects and a second group of samples comprising genomic DNA from a plurality of control subjects; b) performing DNA methylation analysis to determine methylation differences in one or more DNA regions between the first group and second group of samples, wherein a methylation difference in a DNA region is indicative of an epigenetic marker associated with bipolar disease or schizophrenia. The invention also provides one or more epigenetic markers associated with psychosis-associated diseases such as bipolar disease or schizophrenia.Type: ApplicationFiled: January 23, 2008Publication date: September 16, 2010Inventors: Arturas Petronis, Jonathan Mill, James Flanagan, Sun-Chong Wang
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Patent number: 7718746Abstract: Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.Type: GrantFiled: May 22, 2009Date of Patent: May 18, 2010Assignee: Ilypsa, Inc.Inventors: Eric Connor, Dominique Charmot, Han-Ting Chang, Florence Roger, Gerrit Klaerner, Son Hoai Nguyen, Jonathan Mills, Jerry M. Buysse, Angela Lee, Deidre Madsen, Jun Shao, Michael J. Cope, John Fordtran
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Publication number: 20100111891Abstract: The present invention is directed to compositions of a linear polyol and a salt of a crosslinked cation exchange polymer comprising a fluoro group and an acid group. These compositions are useful to bind potassium in the gastrointestinal tract.Type: ApplicationFiled: August 22, 2009Publication date: May 6, 2010Applicant: RELYPSA, INC.Inventors: Detlef Albrecht, Michael Burdick, Han-Ting Chang, Dominique Charmot, Ramakrishnan Chidambaram, Eric Connor, Sherin Halfon, I-Zu Huang, Mingjun Liu, Jonathan Mills, Werner Strüver
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Publication number: 20100029897Abstract: Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.Type: ApplicationFiled: May 22, 2009Publication date: February 4, 2010Applicant: Ilypsa, Inc.Inventors: Eric Connor, Dominique Charmot, Han-Ting Chang, Florence Roger, Gerrit Klaerner, Son Hoai Nguyen, Jonathan Mills, Jerry M. Buysse, Angela Lee, Deidre Madsen, Jun Shao, Michael J. Cope, John Fordtran
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Patent number: 7608674Abstract: Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.Type: GrantFiled: November 3, 2004Date of Patent: October 27, 2009Assignee: Ilypsa, Inc.Inventors: Eric Connor, Dominique Charmot, Han-Ting Chang, Florence Roger, Gerrit Klaerner, Son Hoai Nguyen, Jonathan Mills, Jerry M. Buysse, Angela Lee, Deidre Madsen, Jun Shao, Michael J. Cope, John Fordtran
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Patent number: 7589238Abstract: Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution such that a fraction of the polymer is not available for non-interacting solutes above a certain percentage of the MW of the target ion for the polymer. In some cases, the anion-binding polymers are characterized by low ion-binding interference, where the interference is measured in, for example, a gastrointestinal simulant, relative to non-interfering buffer. Pharmaceutical composition, methods of use, and kits are also described.Type: GrantFiled: August 17, 2006Date of Patent: September 15, 2009Assignee: Ilypsa, Inc.Inventors: Eric Connor, Dominique Charmot, Han Ting Chang, Florence Roger, Gerrit Klaemer, Son Hoai Nguyen, Jonathan Mills, Jerry M. Buysse, Angela Lee, Deidre Madsen, Jun Shao, Michael J. Cope, John Fordtran
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Publication number: 20060284343Abstract: A resin transfer system having an automatic vent system operably associated therewith is provided. The automatic vent system is operable to selectively engage once a predetermined amount of mouldable material has been introduced into the resin transfer system. The automatic vent system can also selectively remove or purge any excess materials, such as excess resin, from the resin transfer system, without having to manually clean any conduits or catch pots.Type: ApplicationFiled: June 20, 2006Publication date: December 21, 2006Applicant: Magna International Inc.Inventors: Paul Trudeau, Lassi Ojanen, David Rouison, Jonathan Mills
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Patent number: 5524845Abstract: A potential target scenery image data is filtered and complex-multiplied h synthetic discriminant functions to produce a two-dimensional, cross-correlated surface. The surface is then analyzed to determine the spatial coordinates of the target, if any.Type: GrantFiled: February 6, 1995Date of Patent: June 11, 1996Assignee: The United States of America as represented by the Secretary of the ArmyInventors: S. Richard F. Sims, Thomas W. Branch, Jonathan A. Mills
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Patent number: D372956Type: GrantFiled: September 15, 1995Date of Patent: August 20, 1996Inventor: Jonathan Mills