Patents by Inventor Jonathan Abel
Jonathan Abel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11966037Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.Type: GrantFiled: May 9, 2022Date of Patent: April 23, 2024Assignee: SamanTree Medical SAInventors: Etienne Shaffer, Jonathan Abel Pirolet, Frédéric Schmitt, Bastien Rachet, Diego Joss, Aurèle Timothée Horisberger
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Publication number: 20230359007Abstract: Disclosed herein are systems for imaging of samples, for example, using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. In some embodiments, detecting optics a reused to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed.Type: ApplicationFiled: June 30, 2023Publication date: November 9, 2023Inventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Patent number: 11747603Abstract: Exemplary systems are for imaging of samples, for example using an array of micro optical elements. In some embodiments, an optical chip including an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. In some embodiments, detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed.Type: GrantFiled: April 29, 2020Date of Patent: September 5, 2023Assignee: SamanTree Medical SAInventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Patent number: 11609416Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.Type: GrantFiled: October 15, 2021Date of Patent: March 21, 2023Assignee: SamanTree Medical SAInventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Publication number: 20230051509Abstract: The implementation of modal processors, which involve the parallel combination resonant filters, may be costly for applications such as artificial reverberation that can require thousands of modes. In one embodiment, the input signal is decomposed into a plurality of subbands, the outputs of which are downsampled. In each downsampled band, resonant filters are applied at the downsampled sampling rate, and their output is upsampled and filtered to form the band output. In these and other embodiments, a feature of responses of the mode filters have been optimized to minimize an aspect of a residual error after a point in time.Type: ApplicationFiled: November 1, 2022Publication date: February 16, 2023Inventor: Jonathan Abel
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Publication number: 20220269059Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.Type: ApplicationFiled: May 9, 2022Publication date: August 25, 2022Inventors: Etienne Shaffer, Jonathan Abel Pirolet, Frédéric Schmitt, Bastien Rachet, Diego Joss, Aurèle Timothée Horisberger
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Patent number: 11333875Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.Type: GrantFiled: January 5, 2021Date of Patent: May 17, 2022Assignee: SamanTree Medical SAInventors: Etienne Shaffer, Jonathan Abel Pirolet, Frédéric Schmitt, Bastien Rachet, Diego Joss, Aurèle Timothée Horisberger
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Publication number: 20220035147Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.Type: ApplicationFiled: October 15, 2021Publication date: February 3, 2022Inventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Patent number: 11181728Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.Type: GrantFiled: August 28, 2020Date of Patent: November 23, 2021Assignee: SamanTree Medical SAInventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Publication number: 20210248746Abstract: Systems and methods to identify and/or reduce or eliminate sample motion artifacts are disclosed. Sample motion artifacts may be reduced or eliminated using scan patterns where an acquisition time difference between when perimeter pixels in adjacent tiles are acquired is reduced, as compared to a conventional raster scan to reduce or eliminate discontinuities that would otherwise appear at tile boundaries in an image. In some embodiments, test images acquired using relatively small test scan patterns or intensities of test points acquired at different times may be compared to determine whether sample motion has occurred. In some embodiments, intensity of adjacent pixels at a tile boundary are compared. In some embodiments, intensity of one or more single pixels is monitored over time to determine whether sample motion has occurred over a period of time. In some embodiments, a flattening or reshaping tool may be used to suppress sample motion during imaging.Type: ApplicationFiled: February 12, 2021Publication date: August 12, 2021Inventors: Andrey Naumenko, Aurèle Timothée Horisberger, Diego Joss, Frédéric Schmitt, Etienne Shaffer, Jonathan Abel Pirolet, Bastien Rachet, Andrew Logvinov
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Publication number: 20210124162Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.Type: ApplicationFiled: January 5, 2021Publication date: April 29, 2021Inventors: Etienne Shaffer, Jonathan Abel Pirolet, Frédéric Schmitt, Bastien Rachet, Diego Joss, Aurèle Timothée Horisberger
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Patent number: 10928621Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.Type: GrantFiled: September 28, 2018Date of Patent: February 23, 2021Assignee: SamanTree Medical SAInventors: Etienne Shaffer, Jonathan Abel Pirolet, Frédéric Schmitt, Bastien Rachet, Diego Joss, Aurèle Timothée Horisberger
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Publication number: 20200393665Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.Type: ApplicationFiled: August 28, 2020Publication date: December 17, 2020Inventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Patent number: 10816788Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.Type: GrantFiled: October 4, 2019Date of Patent: October 27, 2020Assignee: SamanTree Medical SAInventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Frédéric Schmitt
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Publication number: 20200257098Abstract: Disclosed herein are systems for imaging of samples, for example, using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. In some embodiments, detecting optics a reused to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed.Type: ApplicationFiled: April 29, 2020Publication date: August 13, 2020Inventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Publication number: 20200033581Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.Type: ApplicationFiled: October 4, 2019Publication date: January 30, 2020Inventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Patent number: 10539776Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.Type: GrantFiled: September 28, 2018Date of Patent: January 21, 2020Assignee: SamanTree Medical SAInventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss
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Publication number: 20190137752Abstract: Disclosed herein are systems for imaging of samples using an array of micro optical elements and methods of their use. In some embodiments, an optical chip comprising an array of micro optical elements moves relative to an imaging window and a detector in order to scan over a sample to produce an image. A focal plane can reside within a sample or on its surface during imaging. Detecting optics are used to detect back-emitted light collected by an array of micro optical elements that is generated by an illumination beam impinging on a sample. In some embodiments, an imaging system has a large field of view and a large optical chip such that an entire surface of a sample can be imaged quickly. In some embodiments, a sample is accessible by a user during imaging due to the sample being exposed while disposed on or over an imaging window.Type: ApplicationFiled: September 28, 2018Publication date: May 9, 2019Inventors: Etienne Shaffer, Bastien Rachet, Aurèle Timothée Horisberger, Jonathan Abel Pirolet, Diego Joss, Andrey Naumenko, Frédéric Schmitt
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Publication number: 20190129158Abstract: Disclosed herein are sample dishes for use with microscopes that are simple to mount on a microscope and facilitate easy manipulation of tissue samples disposed thereon during imaging as well as methods of their use. A sample dish comprises an optical interface and, optionally, a support member that holds the optical interface. The optical interface of a sample dish is suitably transparent and planar such that a focal plane of a microscope can reside uniformly at or within a surface of a sample during imaging. In certain embodiments, a support member comprises a dish for holding excess fluid. In certain embodiments, a sample dish comprises separation ribs. In certain embodiments, a sample dish comprises one or more manipulation members (e.g., tabs). In certain embodiments, a sample dish is used with an imaging artifact reducing fluid.Type: ApplicationFiled: September 28, 2018Publication date: May 2, 2019Inventors: Etienne Shaffer, Jonathan Abel Pirolet, Frédéric Schmitt, Bastien Rachet, Diego Joss
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Patent number: 10019980Abstract: A reverberator based on a room response modal analysis is adapted to produce distortion, pitch and time manipulation effects, as well as gated and iterated reverberation. An example “modal reverberator” is a parallel collection of resonant filters, with resonance frequencies and dampings tuned to the modal frequencies and decay times of the space or object being simulated. In one example, the resonant filters are implemented as cascades of heterodyning, smoothing, and modulation steps, forming a type of analysis/synthesis architecture. By applying memoryless nonlinearities to the modulating sinusoids, distortion effects are produced, including distortion without intermodulation products. By using different frequencies for the heterodyning and associated modulation operations, pitch manipulation effects are generated, including pitch shifting and spectral “inversion.” By resampling the smoothing filter output, the signal time axis is stretched without introducing pitch changes.Type: GrantFiled: July 1, 2016Date of Patent: July 10, 2018Inventor: Jonathan Abel