Abstract: A general illumination lighting system and/or at least one targeted surface illumination lighting system. The general illumination lighting system including a general illuminating light source configured to generate light toward one or more surfaces or materials to inactivate one or more pathogens on the one or more surfaces or materials. The at least one targeted surface illumination lighting system including one or more targeted surface illuminating light sources that are integrated into or coupled to a plurality of devices, equipment, or fixtures. The one or more targeted surface illuminating light sources configured to generate targeted light toward one or more surfaces of the devices, equipment, or fixtures to inactivate one or more pathogens on the one or more surfaces. The light from the general illuminating light source and the one or more targeted surface illuminating light source including an inactivating portion having wavelengths in a range of 280 to 380 nanometers.

Abstract: Methods and systems are provided for a sealing system for a dynamic nuclear polarization (DNP) system. In one embodiment, a system comprises: a reservoir including an inlet opening; an outer tube; and a tapered seal shaped to seal against the inlet opening and the outer tube, the tapered seal including: a first section removably coupleable to a second section; a through-hole formed by a first plurality of inner surfaces of both the first section and the second section, the through-hole shaped to encircle the outer tube; and a vacuum channel extending through, from an outer surface to an inner surface of the first plurality of inner surfaces, one of the first section and second section. In this way, the tapered seal may be coupled around the fluid passage without inserting a tip of the fluid passage through the through-hole of the tapered seal, thereby maintaining a sterility of the system.

Abstract: A cooling system is provided. The cooling system is associated with a dynamic nuclear polarization system and configured to cool a sample to a temperature suitable for dynamic nuclear polarization to be carried out on the sample while the sample is in the cooling system. The cooling system includes a cryogenic chamber that includes a cryogenic fluid. The cooling system also includes a removable sample sleeve insertable within a portion of the cryogenic chamber. The removable sample sleeve is configured to define a sample path for the sample within the cryogenic chamber that is isolated from other parts of the cooling system.

Abstract: A cooling system is provided. The cooling system is associated with a dynamic nuclear polarization system and configured to cool a sample to a temperature suitable for dynamic nuclear polarization to be carried out on the sample while the sample is in the cooling system. The cooling system includes a cryogenic chamber that includes a cryogenic fluid. The cooling system also includes a removable sample sleeve insertable within a portion of the cryogenic chamber. The removable sample sleeve is configured to define a sample path for the sample within the cryogenic chamber that is isolated from other parts of the cooling system.

Abstract: Methods and systems are provided for a sealing system for a dynamic nuclear polarization (DNP) system. In one embodiment, a system comprises: a reservoir including an inlet opening; an outer tube; and a tapered seal shaped to seal against the inlet opening and the outer tube, the tapered seal including: a first section removably coupleable to a second section; a through-hole formed by a first plurality of inner surfaces of both the first section and the second section, the through-hole shaped to encircle the outer tube; and a vacuum channel extending through, from an outer surface to an inner surface of the first plurality of inner surfaces, one of the first section and second section. In this way, the tapered seal may be coupled around the fluid passage without inserting a tip of the fluid passage through the through-hole of the tapered seal, thereby maintaining a sterility of the system.

Abstract: A general illumination lighting system and/or at least one targeted surface illumination lighting system. The general illumination lighting system including a general illuminating light source configured to generate light toward one or more surfaces or materials to inactivate one or more pathogens on the one or more surfaces or materials. The at least one targeted surface illumination lighting system including one or more targeted surface illuminating light sources that are integrated into or coupled to a plurality of devices, equipment, or fixtures. The one or more targeted surface illuminating light sources configured to generate targeted light toward one or more surfaces of the devices, equipment, or fixtures to inactivate one or more pathogens on the one or more surfaces. The light from the general illuminating light source and the one or more targeted surface illuminating light source including an inactivating portion having wavelengths in a range of 280 to 380 nanometers.

Abstract: A system and method for transporting a hyperpolarized substance is disclosed. A transport vessel for transporting such a hyperpolarized substance includes a vessel housing, a chamber formed within the vessel housing that is configured to receive a container holding a hyperpolarized substance, and an electromagnet configured to generate a magnetic containment field about the chamber when a current is supplied thereto, the magnetic containment field comprising a homogeneous magnetic field. The transport vessel also includes a non-magnetic power source to supply the current to the electromagnet and a control circuit configured to selectively interrupt the supply of current to the electromagnet so as to control generation of the magnetic containment field, with the transport vessel being magnetically inert when the supply of current to the electromagnet is interrupted by the control circuit.

Abstract: A system and method for transporting a hyperpolarized substance is disclosed. A transport vessel for transporting such a hyperpolarized substance includes a vessel housing, a chamber formed within the vessel housing that is configured to receive a container holding a hyperpolarized substance, and an electromagnet configured to generate a magnetic containment field about the chamber when a current is supplied thereto, the magnetic containment field comprising a homogeneous magnetic field. The transport vessel also includes a non-magnetic power source to supply the current to the electromagnet and a control circuit configured to selectively interrupt the supply of current to the electromagnet so as to control generation of the magnetic containment field, with the transport vessel being magnetically inert when the supply of current to the electromagnet is interrupted by the control circuit.

Abstract: An electron paramagnetic resonance imaging (EPRI) system includes a resistive magnet driven by a power supply such as a power supply module to generate radio frequency signals in a substantially coherent polyphase perfect sequence scheme. The EPRI system further includes image acquisition and processing electronics configured to generate, acquire, quantify and map pO2 information associated with a free radical agent in vivo and having a resonance line width that is sensitive to oxygen and in response to the radio frequency signals without imparting harmful heating effects to a corresponding human or animal body.

Abstract: In order to reduce bias associated with conventional ECG analysis, the present invention provides a method and apparatus to improve diagnosis of acute cardiac syndromes (ACS), such as acute myocardial infarction and acute cardiac ischemia (unstable angina), in specified groups of patients using ECG signals and automatic detection analysis. Specific criteria are developed and utilized based on a prespecified group selection for the particular patient. After identifying group membership for the particular patient, ECG data are acquired from a patient experiencing ACS symptoms. Known criteria typically used for assessing ACS are then modified for the particular group membership. Such criteria significantly reduce the bias found in a baseline group for which the known criteria were established.