Patents by Inventor Jonathan ARAMBULA

Jonathan ARAMBULA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TEXAPHYRIN-PT(IV) CONJUGATES AND COMPOSITIONS FOR USE IN OVERCOMING PLATINUM RESISTANCE
    Publication number: 20230113036
    Abstract: The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
    Type: Application
    Filed: June 16, 2022
    Publication date: April 13, 2023
    Inventors: Jonathan L. SESSLER, Jonathan ARAMBULA, Zahid H. SIDDIK, Gregory THIABAUD
  • Texaphyrin-Pt(IV) conjugates and compositions for use in overcoming platinum resistance
    Patent number: 11389459
    Abstract: The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: July 19, 2022
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jonathan L. Sessler, Jonathan Arambula, Zahid H. Siddik, Gregory Thiabaud
  • Naphthoquinone containing gold carbene complexes and methods of uses thereof
    Patent number: 11332483
    Abstract: The present disclosure relates gold carbene naphthoquinone compounds and salts thereof. In some aspects, these compounds can be used to treat cancer including cancers which are resistant to one or more other chemotherapeutic agents such as cisplatin or platinum chemotherapeutic agents. Also provided herein are pharmaceutical compositions comprising the gold carbene naphthoquinone compounds.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: May 17, 2022
    Assignees: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, GEORGIA SOUTHERN UNIVERSITY, WRIGHT STATE UNIVERSITY
    Inventors: Jonathan Arambula, Kuppuswamy Arumugam, Jonathan L. Sessler, Christopher Bielawski
  • NAPHTHOQUINONE CONTAINING GOLD CARBENE COMPLEXES AND METHODS OF USES THEREOF
    Publication number: 20200216473
    Abstract: The present disclosure relates gold carbene naphthoquinone compounds and salts thereof. In some aspects, these compounds can be used to treat cancer including cancers which are resistant to one or more other chemotherapeutic agents such as cisplatin or platinum chemotherapeutic agents. Also provided herein are pharmaceutical compositions comprising the gold carbene naphthoquinone compounds.
    Type: Application
    Filed: June 29, 2018
    Publication date: July 9, 2020
    Inventors: Jonathan ARAMBULA, Kuppuswamy ARUMUGAM, Jonathan L. SESSLER, Christopher BIELAWSKI
  • TEXAPHYRIN-PT(IV) CONJUGATES AND COMPOSITIONS FOR USE IN OVERCOMING PLATINUM RESISTANCE
    Publication number: 20200069698
    Abstract: The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
    Type: Application
    Filed: September 6, 2019
    Publication date: March 5, 2020
    Inventors: Jonathan L. SESSLER, Jonathan ARAMBULA, Zahid H. SIDDIK, Gregory THIABAUD
  • Texaphyrin-Pt(IV) conjugates and compositions for use in overcoming platinum resistance
    Patent number: 10406167
    Abstract: The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: September 10, 2019
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Jonathan L. Sessler, Jonathan Arambula, Zahid H. Siddik, Gregory Thiabaud
  • TEXAPHYRIN-PT(IV) CONJUGATES AND COMPOSITIONS FOR USE IN OVERCOMING PLATINUM RESISTANCE
    Publication number: 20170246182
    Abstract: The present disclosure relates platinum(IV) and texaphyrin linked conjugates and compositions comprising a texaphyrin and a platinum(IV) agent. The present disclosure also provides pharmaceutical compositions of the conjugates and compositions. Also, provided herein are methods of using the instant compounds in the treatment of cancer such as a platinum resistant cancer.
    Type: Application
    Filed: June 11, 2015
    Publication date: August 31, 2017
    Inventors: Jonathan L. SESSLER, Jonathan ARAMBULA, Zahid H. SIDDIK, Gregory THIABAUD