Abstract: A method of operating an ion mobility spectrometer comprises the following steps: drawing a sample of gaseous fluid into a reaction region of the ion mobility spectrometer; providing a first pulse of a pulsed ionisation source to ionise the sample of gaseous fluid, thereby to obtain first sample ions; after a first gate delay following the first trigger opening an ion shutter to permit a portion of the first sample ions to leave the reaction region; providing a second pulse of the pulsed ionisation source to further ionise the sample of gaseous fluid, thereby to obtain second sample ions; after a second gate delay following the first trigger opening the ion shutter to permit a portion of the second sample ions to leave the reaction region, wherein the second gate delay is different from the first gate delay.

Abstract: An ion filter for a mass spectrometer, the apparatus comprising an ion modifier; an ion selector configured to select a subset of a sample of ions based on their mobility in a gas; and a controller configured to operate the ion modifier in a first mode to modify the ions selected by the ion selector to provide daughter ions, and configured to operate the ion modifier in a second mode to output the ions selected by the ion selector; wherein the ion filter is adapted for providing output ions from the ion modifier to an intake of a mass spectrometer.

Abstract: A method and system for migrating contact data from a source customer relationship management (CRM) system to a target CRM system, comprising retrieving a source contact record corresponding to a source contact from a source CRM database associated with the source CRM system, the source contact record including a first set of data fields populated with information about the source contact; retrieving, from a support database, a support contact record corresponding to the source contact, the support contact record including a second set of data fields populated with information about the source contact; and determining, based on information included in the support contact record, if the source contact record meets a predefined migration criteria, and if so perform a migration process to migrate information included in the source contact record to the target CRM system.

Abstract: An ion mobility spectrometer comprising an ioniser for ionising a sample; a detector separated from the ioniser by a drift chamber along which ions can travel from the ioniser toward the detector; a gate for controlling the passage of ions from the ioniser to the drift chamber; an ion modifier arranged between the ioniser and the detector and comprising a first electrode and a second electrode; and a voltage provider configured to provide a time varying voltage between the first electrode and the second electrode wherein the time varying voltage has a frequency of at least 2.5 MHz.

Abstract: An on-demand vapour generator includes a vapour chamber configured to produce a vapour and a vapour absorption assembly configured to receive flows of vapour from the vapour chamber. The vapour absorption assembly includes a first vapour-permeable passage having a passage outlet and at least one second vapour-permeable passage that is closed. When vapour absorption assembly receives a flow of vapour from the vapour chamber, the flow of vapour passes through the first vapour-permeable passage to the passage outlet at least substantially without absorption of vapour from the flow of vapour. However, when a flow of vapour is not received from the vapour chamber, vapour entering the vapour absorption assembly from the vapour chamber passes into the first vapour-permeable passage and the at least one second vapour-permeable passage and is at least substantially absorbed.

Abstract: An ion filter for a mass spectrometer, the apparatus compr sing an ion inodifier; an ion selector configured to select a subset of a sample of ions based on their mobility in a gas; and a controller configured to operate the ion modifier in a first mode to modify the ions selected by the ion selector to provide daughter ions, and configured to operate the ion modifier in a second mode to Coutput the ions selected by the ion selector;wherein the ion filter is adapted for providing output ions from the ion modifier to an in-take of a mass spectrometer.

Abstract: An ionising apparatus for ionising a sample of gaseous fluid. The ionising apparatus comprises an ioniser configured to provide reactant ions; an ion modifier configured to modify the reactant ions, and a reaction region arranged to receive the modified reactant ions and a sample and to combine the sample with the modified reactant ions to ionise the sample for analysis by a detector configured to identify a substance of interest in the sample.

Abstract: An ion mobility spectrometer comprising an ioniser for ionising a sample; a detector separated from the ioniser by a drift chamber along which ions can travel from the ioniser toward the detector; a gate for controlling the passage of ions from the ioniser to the drift chamber; an ion modifier arranged between the ioniser and the detector and comprising a first electrode and a second electrode; and a voltage provider configured to provide a time varying voltage between the first electrode and the second electrode wherein the time varying voltage has a frequency of at least 2.5 MHz.

Abstract: An ion filter for a mass spectrometer, the apparatus comprising an ion modifier; an ion selector configured to select a subset of a sample of ions based on their mobility in a gas; and a controller configured to operate the ion modifier in a first mode to modify the ions selected by the ion selector to provide daughter ions, and configured to operate the ion modifier in a second mode to output the ions selected by the ion selector; wherein the ion filter is adapted for providing output ions from the ion modifier to an intake of a mass spectrometer.

Abstract: Ion modification An ion mobility spectrometer (100) comprising a sample inlet (108) comprising an aperture arranged to allow a sample of gaseous fluid to flow from an ambient pressure region to a low pressure region of the ion mobility spectrometer to be ionised; a controller (200) arranged to control gas pressure in the low pressure region to be lower than ambient pressure; and an ion modifier (126, 127, 202) configured to modify ions in the low pressure region, wherein the ions are obtained from the sample of gas.

Abstract: An ion mobility spectrometer comprising an ionizer for ionizing a sample; a detector separated from the ionizer by a drift chamber along which ions can travel from the ionizer toward the detector; a gate for controlling the passage of ions from the ionizer to the drift chamber; an ion modifier arranged between the ionizer and the detector and comprising a first electrode and a second electrode; and a voltage provider configured to provide a time varying voltage between the first electrode and the second electrode wherein the time varying voltage has a frequency of at least 2.5 MHz.

Abstract: Ion modification An ion mobility spectrometer (100) comprising a sample inlet (108) comprising an aperture arranged to allow a sample of gaseous fluid to flow from an ambient pressure region to a low pressure region of the ion mobility spectrometer to be ionised; a controller (200) arranged to control gas pressure in the low pressure region to be lower than ambient pressure; and an ion modifier (126, 127, 202) configured to modify ions in the low pressure region, wherein the ions are obtained from the sample of gas.

Abstract: An on-demand vapour generator includes a vapour chamber configured to produce a vapour and a vapour absorption assembly configured to receive flows of vapour from the vapour chamber. The vapour absorption assembly includes a first vapour-permeable passage having a passage outlet and at least one second vapour-permeable passage that is closed. When vapour absorption assembly receives a flow of vapour from the vapour chamber, the flow of vapour passes through the first vapour-permeable passage to the passage outlet at least substantially without absorption of vapour from the flow of vapour. However, when a flow of vapour is not received from the vapour chamber, vapour entering the vapour absorption assembly from the vapour chamber passes into the first vapour-permeable passage and the at least one second vapour-permeable passage and is at least substantially absorbed.

Abstract: Ion modification An ion mobility spectrometer (100) comprising a sample inlet (108) comprising an aperture arranged to allow a sample of gaseous fluid to flow from an ambient pressure region to a low pressure region of the ion mobility spectrometer to be ionized; a controller (200) arranged to control gas pressure in the low pressure region to be lower than ambient pressure; and an ion modifier (126, 127, 202) configured to modify ions in the low pressure region, wherein the ions are obtained from the sample of gas.

Abstract: An on-demand vapor generator includes a vapor chamber configured to produce a vapor and a vapor absorption assembly configured to receive flows of vapor from the vapor chamber. The vapor absorption assembly includes a first vapor-permeable passage having a passage outlet and at least one second vapor-permeable passage that is closed. When vapor absorption assembly receives a flow of vapor from the vapor chamber, the flow of vapor passes through the first vapor-permeable passage to the passage outlet at least substantially without absorption of vapor from the flow of vapor. However, when a flow of vapor is not received from the vapor chamber, vapor entering the vapor absorption assembly from the vapor chamber passes into the first vapor-permeable passage and the at least one second vapor-permeable passage and is at least substantially absorbed.

Abstract: An ionising apparatus for ionising a sample of gaseous fluid. The ionising apparatus comprises an ioniser configured to provide reactant ions; an ion modifier configured to modify the reactant ions, and a reaction region arranged to receive the modified reactant ions and a sample and to combine the sample with the modified reactant ions to ionise the sample for analysis by a detector configured to identify a substance of interest in the sample.

Abstract: An ionizing apparatus for ionizing a sample of gaseous fluid. The ionizing apparatus comprises an ionizer configured to provide reactant ions; an ion modifier configured to modify the reactant ions, and a reaction region arranged to receive the modified reactant ions and a sample and to combine the sample with the modified reactant ions to ionize the sample for analysis by a detector configured to identify a substance of interest in the sample.

Abstract: An on-demand vapour generator includes a vapour chamber configured to produce a vapour and a vapour absorption assembly configured to receive flows of vapour from the vapour chamber. The vapour absorption assembly includes a first vapour-permeable passage having a passage outlet and at least one second vapour-permeable passage that is closed. When vapour absorption assembly receives a flow of vapour front the vapour chamber, the flow of vapour passes through the first vapour-permeable passage to the passage outlet at least substantially without absorption of vapour from the flow of vapour. However, when a flow of vapour is not received from the vapour chamber, vapour entering the vapour absorption assembly from the vapour chamber passes into the first vapour-permeable passage and the at least one second vapour-permeable passage and is at least substantially absorbed.

Abstract: Ion modification An ion mobility spectrometer (100) comprising a sample inlet (108) comprising an aperture arranged to allow a sample of gaseous fluid to flow from an ambient pressure region to a low pressure region of the ion mobility spectrometer to be ionised; a controller (200) arranged to control gas pressure in the low pressure region to be lower than ambient pressure; and an ion modifier (126, 127, 202) configured to modify ions in the low pressure region, wherein the ions are obtained from the sample of gas.

Abstract: An ion filter for a mass spectrometer, the apparatus comprising an ion modifier; an ion selector configured to select a subset of a sample of ions based on their mobility in a gas; and a controller configured to operate the ion modifier in a first mode to modify the ions selected by the ion selector to provide daughter ions, and configured to operate the ion modifier in a second mode to output the ions selected by the ion selector; wherein the ion filter is adapted for providing output ions from the ion modifier to an intake of a mass spectrometer.