Patents by Inventor Jonathan Axon

Jonathan Axon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bi-cyclic pyrimidine inhibitors of TGF?
    Patent number: 7223766
    Abstract: Compounds in which a pyrimidine nucleus is bridged at the 5 and 6 position and are further substituted at positions 2 and 4 with substituents comprising aromatic moieties are useful in treating subjects with rheumatoid arthritis ameliorated by inhibition of TGF? activity.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: May 29, 2007
    Assignee: Scios, Inc.
    Inventors: Sundeep Dugar, Sarvajit Chakravarty, Aurelia Conte, Jonathan Axon, Glenn McEnroe, Alison Murphy
  • Fused bicyclic inhibitors of TGFbeta
    Publication number: 20070066632
    Abstract: Certain appropriately substituted fused bicyclic pyrimidine compounds having an amide-substituted pyridylamine group at C-4 of the pyrimidine ring are useful in the treatment of conditions associated with excessive TGF? activity and certain viral disorders.
    Type: Application
    Filed: March 27, 2006
    Publication date: March 22, 2007
    Applicant: Scios, Inc.
    Inventors: Barry Hart, Sarvajit Chakravarty, Jonathan Axon, Alison Murphy, Glenn McEnroe
  • Carboxamide inhibitors of TGFbeta
    Publication number: 20060281763
    Abstract: Certain appropriately substituted forms of pyrimidine having a pyridylamine group at C-4 of the pyrimidine and an amide group on the pyridine ring are useful in the treatment of conditions associated with excessive TGF? activity.
    Type: Application
    Filed: March 27, 2006
    Publication date: December 14, 2006
    Inventors: Jonathan Axon, Sarvajit Chakravarty, Barry Hart, Glenn McEnroe, Alison Murphy, Karen Pontius, Peijue Sheng, Xiaojing Wang, Shanthi Yellapregada
  • Bi-cyclic pyrimidine inhibitors of TGFbeta
    Publication number: 20050004143
    Abstract: Compounds in which a pyrimidine nucleus is bridged at the 5 and 6 position and are further substituted at positions 2 and 4 with substituents comprising aromatic moieties are useful in treating subjects with conditions ameliorated by inhibition of TGF? activity.
    Type: Application
    Filed: March 26, 2004
    Publication date: January 6, 2005
    Inventors: Sundeep Dugar, Sarvajit Chakravarty, Aurelia Conte, Jonathan Axon, Glenn McEnroe, Alison Murphy
  • Inhibitors of TGFbeta
    Publication number: 20040132730
    Abstract: Certain appropriately substituted forms of pyrimidine and triazine are useful in the treatment to conditions associated with enhanced TGF&bgr; activity.
    Type: Application
    Filed: September 10, 2003
    Publication date: July 8, 2004
    Inventors: Jonathan Axon, Sarvajit Chakravarty, Sundeep Dugar, Glenn McEnroe, Alison Murphy