Patents by Inventor Jonathan B. DeCamp

Jonathan B. DeCamp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones
    Patent number: 7947850
    Abstract: The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: May 24, 2011
    Assignee: Inspire Pharmaceuticals, Inc.
    Inventors: Jonathan B. DeCamp, Paul S. Watson, Jin She
  • METHOD FOR TREATING INFLAMMATORY CONDITIONS
    Publication number: 20100160250
    Abstract: This invention provides a method for inhibiting the release of interleukin-1? in a mammal. This invention also provides a method for preventing or treating pulmonary diseases, ophthalmic diseases, and autoimmune diseases that are associated with inflammation or inflammatory conditions. The invention also provides a method for preventing or treating neurodegenerative diseases, or pain in a mammal. The method comprises administering to a mammal in need thereof a therapeutically effective amount of a mononucleoside compound, which is an antagonist of P2X7 receptor.
    Type: Application
    Filed: December 17, 2009
    Publication date: June 24, 2010
    Inventors: James G. Douglass, III, Sammy R. Shaver, Tomas Navratil, José L. Boyer, Carl A. Samuelson, Jonathan B. DeCamp
  • PROCESS FOR THE PREPARATION OF 3,4-DISUBSTITUTED-THIAZOLIDIN-2-ONES
    Publication number: 20080287683
    Abstract: The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.
    Type: Application
    Filed: July 30, 2008
    Publication date: November 20, 2008
    Inventors: Jonathan B. DeCamp, Paul S. Watson, Jin She
  • Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones
    Patent number: 7414137
    Abstract: The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: August 19, 2008
    Assignee: Inspire Pharmaceuticals, Inc.
    Inventors: Jonathan B. DeCamp, Paul S. Watson, Jin She
  • PROCESS FOR THE PREPARATION OF 3,4-DISUBSTITUTED-THIAZOLIDIN-2-ONES
    Publication number: 20070225504
    Abstract: The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compounds of 3,4-disubstituted-thiazolidin-2-ones. The compounds prepared by the present invention are useful in the synthesis and manufacture of compounds (such as latrunculins and/or their analogs) for treating diseases or conditions associated with inhibiting actin polymerization.
    Type: Application
    Filed: March 22, 2007
    Publication date: September 27, 2007
    Inventors: Jonathan B. DeCamp, Paul S. Watson, Jin She