Abstract: The present invention provides methods for treating cancer using a6*nAChR inhibitors, such as a6*nAChR inhibitory antibodies, among others. The invention also features compositions containing a6*nAChR inhibitors, methods of diagnosing patients with a6*nAChR-associated cancer, and methods of predicting the response of cancer in a subject to treatment with a6*nAChR inhibitors.

Abstract: The present invention provides methods for treating inflammatory or autoimmune diseases or conditions using serotonin receptor activators, such as serotonin receptor activating antibodies, among others. The invention also features compositions containing serotonin receptor activators, methods of diagnosing patients with a serotonin receptor-associated inflammatory or autoimmune disease or condition, and methods of predicting the response of an inflammatory or autoimmune disease or condition in a subject to treatment with serotonin receptor activators.

Abstract: Described herein are methods for treating a subject having or at risk of developing an autoimmune or inflammatory condition or an infection by administering a neuromodulating agent.

Abstract: The present invention provides methods for treating inflammatory or autoimmune disease using mGluR8 activators, such as mGluR8 activating antibodies, among others. The invention also features compositions containing mGluR8 activators, methods of diagnosing patients with mGluR8-associated inflammatory or autoimmune disease, and methods of predicting the response of an inflammatory or autoimmune disease or condition in a subject to treatment with mGluR8 activators.

Abstract: Described herein are methods for treating a subject having or at risk of developing cancer by administering a neuromodulating agent.

Abstract: The present invention provides methods for treating cancer using serotonin receptor inhibitors, such as serotonin receptor inhibitory antibodies, among others. The invention also features compositions containing serotonin receptor inhibitors, methods of diagnosing patients with serotonin receptor-associated cancer, and methods of predicting the response of cancer in a subject to treatment with serotonin receptor inhibitors.

Abstract: Described herein are methods for treating a subject having or at risk of developing cancer administering a neuromodulating agent.

Abstract: The present invention provides methods for treating cancer using sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump inhibitors, such as SERCA pump inhibitory antibodies, among others. The invention also features compositions containing SERCA pump inhibitors, methods of diagnosing patients with SERCA pump-associated cancer, and methods of predicting the response of cancer in a subject to treatment with SERCA pump inhibitors.

Abstract: The present invention provides methods for treating inflammatory or autoimmune diseases or conditions using activators tin of nicotinic acetylcholine receptors (nAChRs) containing a cholinergic receptor nicotinic alpha 6 subunit (nAChR?S), such as activating antibodies that bind to a nAChR containing a nAChP?6 subunit and small molecule agonists of nAChRs containing a nAChR?S subunit. The invention also features compositions containing ?6*nAChR activators, methods of diagnosing patients with an ?6*nAChR-associated inflammatory or autoimmune disease or condition, and methods of predicting the response of an inflammatory or autoimmune disease or condition in a subject to treatment with ?6*nAChR activators.

Abstract: The present invention provides methods for treating cancer using mGluR8 inhibitors, such as mGluR8 inhibitory antibodies and small molecules. The invention also features compositions containing mGluR8 inhibitors, methods of diagnosing patients with mGluR8-associated cancer, and methods of predicting the response of cancer in a subject to treatment with mGluR8 inhibitors.

Abstract: Embodiments relate to illuminated electrosurgical devices and related systems and methods. An electrosurgical device can include an electrosurgical blade having a proximal end and a distal end and comprising a plurality of light elements. A plurality of separation walls and a plurality of apertures can be arranged relative to the plurality of light elements to guide light from the plurality of light elements to illuminate an area around the distal end of the electrosurgical blade.

Abstract: The present invention provides methods for treating cancer using P2RX2 inhibitors, such as P2RX2 inhibitory antibodies, among others. The invention also features compositions containing P2RX2 inhibitors, methods of diagnosing patients with P2RX2-associated cancer, and methods of predicting the response of cancer in a subject to treatment with P2RX2 inhibitors.

Abstract: Described herein are methods for treating a subject having or at risk of developing cancer administering a neuromodulating agent.

Abstract: The present invention provides methods for treating inflammatory or autoimmune disease using calcitonin receptor activators, such as calcitonin receptor activating antibodies, among others. The invention also features compositions containing calcitonin receptor activators, methods of diagnosing patients with calcitonin receptor-associated inflammatory or autoimmune disease, and methods of predicting the response of an inflammatory or autoimmune disease or condition in a subject to treatment with calcitonin receptor activators.

Abstract: Enhanced printing solutions are enabled by providing ultraviolet curing conditions without requiring complete evacuation of atmospheric oxygen. Increased ink coverage and adjusted surface appearance are also provided.

Abstract: Method for testing multiple signal transceiver devices under test (DUTs), such as data packet signal transceivers, with a shared DUT testing resource, such as a tester having a single vector signal generator (VSG) and a single vector signal analyzer (VSA). Requests by the DUTs for access to tester resources (e.g., to receive signals from the signal generator or provide signals to the signal analyzer) are prioritized based upon tester availability and whether the requesting DUT requires sole access or can share access to the tester. If the tester is unavailable, DUT requests are queued according to their respective priorities to await tester availability. As a result, access to shared tester resources can be managed dynamically to minimize test time while testing multiple DUTs concurrently.

Abstract: The disclosure provides a fluid-assisted electrosurgical device. The device comprises a first electrode, a second electrode and at least one fluid outlet. In one embodiment, the first electrode has a distal portion with an electrically conductive spherical surface, the second electrode has a distal portion with an electrically conductive spherical surface, and at least one of the first electrode and the second electrode have a blade portion.

Abstract: A system and method for facilitating comparison of radio frequency (RF) data signals transmitted by a device under test (DUT) and received by a test system. A RF data signal received from a DUT is analyzed to provide analysis data indicative of conformance of the DUT operation with one or more applicable signal standards. The RF data signal is also converted to related conversion data that can be stored with state machine data corresponding to states of the signal testing subsystem. This state machine data can then be processed as needed with the analysis data and conversion data for off-line tasks such as debugging new test programs and procedures.

Abstract: System and method for using a shared packet data signal source to test multiple packet data signal transceiver devices under test (DUTs) capable of communicating using multiple radio access technologies (RATs). The signal source provides a packet data signal that includes a plurality of sequential signal segments having respective signal timing parameters and mutually distinct signal characteristics in accordance with the RATs. Based upon the signal timing parameters, at least a portion of each signal segment is routed to a respective one of multiple signal connections for conveyance to a corresponding DUT.