Abstract: An embodiment of a composition for target material separation includes: a body and one or more molecules coupled to the body and structured for functionalization of the composition. In embodiments, each of the one or more molecules can include one or more of: a linker region; a polymerase chain reaction (PCR) segment or oligo binding region; one or more barcode region(s); a unique molecule identifier; a preparation-facilitating segment; an active segment; and a molecular scissor or cleavage region, wherein various regions can be coupled together in order to provide functionality to the composition. The invention(s) also cover manufacturing of the composition and various applications of use, in the context of target material capture (e.g., from single cells or other biological material).

Abstract: The field of this invention relates to immunohistochemistry (IHC), immunocytochemistry and in situ hybridization (ISH) for the targeted detection and mapping of biomolecules (e.g., proteins, glycans and RNAs) in tissues or cells for example, for research use and for clinical use such by pathologists (e.g., biomarker analyses of a resected tumor or tumor biopsy). In particular, the use of mass spectrometric imaging (MSI) as a mode to detect and map the biomolecules in tissues or cells for example. More specifically, the field of this invention relates to photocleavable mass-tag reagents which are attached to Probes such as antibodies and nucleic acids and used to achieve multiplex immunohistochemistry, immunocytochemistry and in situ hybridization, with mass spectrometry (MS) and mass spectrometry imaging (MSI) as the mode of detection/readout.

Abstract: An intermittent network connection between a source system and a destination system is established by establishing a first connection from a management resource to a first port of the destination system, causing a second port of the destination system to be enabled including by providing an instruction via the first connection to the first port of the destination system, establishing a second connection from the management resource to a first port of a source system, causing a second port of the source system to be enabled including by providing an instruction via the second connection to the first port of the source system, registering the destination system with the source system, and causing a third connection to be established between the second port of the source system and the second port of the destination system for transferring data from the source system to the destination system.

Abstract: An indication to perform a backup of data stored in a persistent storage associated with a source system is received. In response to the indication to perform the backup, current execution information at least in part maintained in a volatile memory is captured. The captured current execution information is caused to be stored with backup data from the backup of the data stored in the persistent storage.

Abstract: A computing device, a computer program product, and a computer-implemented method for utilizing predictive modeling in order to predict whether a driver of a vehicle is ultimately going to return to his/her house. If it is predicted that the driver is intending to return to his/her house, then an automatic action may be taken, such as opening a garage door to the house. A machine learning model may be added to the system to improve accuracy of the prediction.

Abstract: An indication to perform a backup of data stored in a persistent storage associated with a source system is received. In response to the indication to perform the backup, current execution information at least in part maintained in a volatile memory is captured.

Abstract: An embodiment of a composition for target material separation includes: a body and one or more molecules coupled to the body and structured for functionalization of the composition. In embodiments, each of the one or more molecules can include one or more of: a linker region; a polymerase chain reaction (PCR) segment or oligo binding region; one or more barcode region(s); a unique molecule identifier; a preparation-facilitating segment; an active segment; and a molecular scissor or cleavage region, wherein various regions can be coupled together in order to provide functionality to the composition. The invention(s) also cover manufacturing of the composition and various applications of use, in the context of target material capture (e.g., from single cells or other biological material).

Abstract: A system for neutralizing airborne microorganisms includes a conditioning section for accommodating a flow of air, the conditioning section including an air inlet; an air outlet; a packing chamber located downstream relative to the air inlet, a distribution chamber located downstream relative to the packing chamber and located above the packing chamber, the distribution chamber including at least one spray nozzle for spraying a liquid desiccant into the distribution chamber towards the packing chamber; a sump located below the packing chamber; a pump for propelling the liquid desiccant from the sump to the at least one spray nozzle; a droplet collection chamber located downstream relative to the at least one spray nozzle for removing droplets from the flow of air flowing through the droplet collection chamber; and a UV disinfection chamber located downstream relative to the droplet collection chamber and upstream relative to the air outlet.

Abstract: The PROCESS TRANSFORMATION AND TRANSITIONING APPARATUSES, METHODS AND SYSTEMS (“PTT”) transform unoptimized locally-deployable baseline processes via PTT components into custom globally optimized processes and transition materials. In one implementation, the PTT obtains a baseline process optimization request via a processor, including a unoptimized locally-deployable baseline process. The PTT provides a notification of receipt of the baseline process optimization request, obtains a sub-process identification input, and resolves, via the processor, the unoptimized locally-deployable baseline process into one or more baseline sub-processes. Also, the PTT accesses a process template database for sub-process templates matching the resolved baseline sub-processes, and identifies, via the processor, sub-process templates matching the resolved baseline sub-processes using a matching procedure.

Abstract: An improved method and system for managing the traceability of numerical, alphabetical, alphanumeric, character, or string entities such as critical constants or key calculations, equations, functions, and procedures that automatically enables the traceability of information entities without requiring significant manual intervention by a system user. The system allows a user to enter critical information such a critical constant or key calculation into a first document. When the user copies/exports the critical information from the first document and pastes/imports the information to a second document, the system automatically generates meta-data describing the provenance of the information, and propagates the provenance meta-data from the first document to the second document.

Abstract: An improved method and system for managing the traceability of numerical, alphabetical, alphanumeric, character, or string entities such as critical constants or key calculations, equations, functions, and procedures that automatically enables the traceability of information entities without requiring significant manual intervention by a system user. The system allows a user to enter critical information such a critical constant or key calculation into a first document. When the user copies/exports the critical information from the first document and pastes/imports the information to a second document, the system automatically generates meta-data describing the provenance of the information, and propagates the provenance meta-data from the first document to the second document.

Abstract: This document describes the design and control of a flexible, electronic display screen mechanism. The display may emit, reflect, or otherwise control visible and invisible light such that a viewer may see graphical shapes, text based characters, or time varying images on the screen. The flexibility of the display screen allows it to be physically bent, curved, wrapped, or molded without causing breakage or otherwise deteriorating the performance of the device. This flexibility allows these displays to be used, for example, within items of clothing.

Abstract: An convertible, footwear attachment device and methods of configuring it and using it on a primary footwear to provide resistance to slippage on snow, ice or other slick surfaces. The attachment device is of the sling-type, full-sole unit and is formed of an elastic, flexible and severable material. The full-sole unit is made up of a sole, a toe attachment assembly, a heel attachment assembly, and visible indicia, e.g., grooves, for indicating the boundaries of a removable portion of the full-sole unit which may be severed therefrom to form the half-sole unit. The attachment assemblies enable the device to be releasably mounted on the primary footwear irrespective of whether the device is converted from the full-sole unit to the half-sole unit or not. The sole and heel portions of the full-sole unit each include plural hard, ice-gripping projections, e.g., spikes.

Abstract: An ice-gripping attachment device for securement to the sole of primary footwear, e.g., a boot. The attachment device includes comprises a front section, a rear section, and a pair of straps interconnecting the sections. The front section includes a front sole portion having a toe box disposed over it. The rear section includes a rear sole portion and a heel cup disposed over it. The toe box is adapted for accommodating the toe portion of the boot, while the heel cup is arranged for accommodating the heel portion of the boot. The pair of straps interconnect the toe box and the heel cup along the medial and lateral sides of the boot and are located above the front sole portion and the rear sole portion so that they do not contact the ground when attachment device is in place on the boot. The straps are arranged to be releasably secured together by VELCRO.RTM.

Abstract: An ice-gripping sandal for releasable mounting on the foot of a person or on the sole of a boot or other primary footwear worn by the person. The sandal comprises a sole, a toe strapping assembly and a heel strapping assembly for mounting the sandal on the boot. The sandal's sole has a bottom surface having plural groups of cleats projecting therefrom. Some of the cleats are located within a forefoot and toe portion of the sole and extend at an acute angle to the longitudinal axis of the sole. These cleats include end portions having respective ice-gripping screws mounted therein. Grooves are provided between the cleats in the forefoot and toe portions of the sole, with the width and depth of the grooves increasing from the medial side of the sole to the lateral side of the sole. The grooves enable material which may tend to adhere to the sole within the grooves to be forced out of the grooves when the wearer walks.