Abstract: Novel tissue wound closure devices and applicator instruments are disclosed. The tissue wound closure devices have a filament or strap and a capture device that locks the filament or strap in place after application to approximate a wound in tissue. The applicator instruments have a curved insertion needle.

Abstract: Novel tissue wound closure devices and applicator instruments are disclosed. The tissue wound closure devices have a filament or strap and a capture device that locks the filament or strap in place after application to approximate a wound in tissue. The applicator instruments have a curved insertion needle.

Abstract: A vaginal insert has a flexible body either in the form of a belt or a split cylinder. In either case, the insert may be coiled into a coiled state. The body has a reduced diameter when coiled and exhibits a resilient bias toward uncoiling and expanding in diameter from the coiled state. When the insert is inserted into the vagina of a patient, it expands and presses against the vaginal wall. This pressure in itself may be therapeutic, e.g., in treating cystocele and incontinence. A medicament may be conjoined with the insert that is introduced to the patient through contact with the insert. The insert can have a simultaneous mechanical and pharmacological effect, e.g., in the instance of treating incontinence with a drug and pressure. The belt-type body may incorporate mating ridges and grooves to keep the insert in a cylindrical configuration. Latch elements may be incorporated on the insert to support the insert in an expanded, partially uncoiled state.

Abstract: A vaginal insert has a flexible body either in the form of a belt or a split cylinder. In either case, the insert may be coiled into a coiled state. The body has a reduced diameter when coiled and exhibits a resilient bias toward uncoiling and expanding in diameter from the coiled state. When the insert is inserted into the vagina of a patient, it expands and presses against the vaginal wall. This pressure in itself may be therapeutic, e.g., in treating cystocele and incontinence. A medicament may be conjoined with the insert that is introduced to the patient through contact with the insert. The insert can have a simultaneous mechanical and pharmacological effect, e.g., in the instance of treating incontinence with a drug and pressure. The belt-type body may incorporate mating ridges and grooves to keep the insert in a cylindrical configuration. Latch elements may be incorporated on the insert to support the insert in an expanded, partially uncoiled state.