Abstract: Apparatus and methods for a prosthetic heart valve are provided. The apparatus may include a prosthetic heart-valve fitting. The fitting may be seated in a valve annulus of the heart. The fitting may be a fitting that does not include a tissue-penetrating anchor. The fitting may be a fitting that does not include a tissue-penetrating barb. The apparatus may include a brace. The brace may be urged by an atrial tissue of the heart to maintain a position of the fitting in the annulus.

Abstract: Various implementations, systems and methods are disclosed for continuous, near real-time, hands-off sampling of airborne particulate matter, and qualification and/or quantification of biomolecules in the sample representative for biologic or microbial contamination. The systems and methods may utilize an electrostatic precipitator for sampling the matter; and a measurement assembly configured to illuminate, excite, or breakdown the sampled matter by electromagnetic radiation, and to detect a spectrum, or one or more wavelength bands of the scatter emitted by the sample. In an exemplary implementation, a sputter deposition process is employed to configure the sample for an enhanced plasmon resonance. The measurement data may be transferred via wireless communication means for cloud storage and signal processing.

Abstract: A collapsible and expandable prosthetic mitral valve stent is provided with improved recapture into a distal lumen of a delivery sheath. Various embodiments comprise a valve support within the interior of a stent frame and defining a flow channel therethrough, wherein the top or upstream of the valve support comprises a row, or a plurality, of stent cells that are bent radially inward at least partially over the flow channel. Some embodiments may comprise a recapture assist mechanism, such as an open paddle, attached to one or more of the inwardly bent stent cells and adapted to receive and/or engage a wire to aid in positioning, expansion, recapture and/or implanting the device in a patient's heart chamber.

Abstract: Apparatus and methods for treatment of a bone. The apparatus may include an implant. The implant may include an implant tail and an implant head configured to expand, inside the bone, from a collapsed state to an expanded state. The apparatus may include an intramedullary rod defining a central longitudinal rod axis. The intramedullary rod may include a guide segment configured to guide the implant head into the bone and support the implant tail. The intramedullary rod may include an elongated extension member spaced radially apart from the central longitudinal axis. The extension member may be configured to provide clearance for the implant head as the implant head is advanced, in the collapsed state, into the bone. The extension member may be configured to provide clearance for the implant head in the expanded state.

Abstract: Apparatus and methods for treatment of a bone. The apparatus may include an implant. The implant may include an implant tail and an implant head configured to expand, inside the bone, from a collapsed state to an expanded state. The apparatus may include an intramedullary rod defining a central longitudinal rod axis. The intramedullary rod may include a guide segment configured to guide the implant head into the bone and support the implant tail. The intramedullary rod may include an elongated extension member spaced radially apart from the central longitudinal axis. The extension member may be configured to provide clearance for the implant head as the implant head is advanced, in the collapsed state, into the bone. The extension member may be configured to provide clearance for the implant head in the expanded state.

Abstract: Apparatus and methods for delivery of an implant at a target site in an interior of a bone. The apparatus may include a plate. The plate may include a bottom surface complementing a surface contour of a bone. The plate may define first holes sized for receiving screws. The plate may define second holes sized for receiving fixation elements. The plate may define an opening. The opening may be sized for providing passage of the implant through the plate. When the bottom surface is seated complementarily against the surface contour, the first holes may point into an interior of the bone and into a volume occupied by the implant in the interior when the implant is positioned at a target site and radially expanded to form a mesh cage.

Abstract: Apparatus and methods for treatment of a bone. The apparatus may include an implant. The implant may include an implant tail and an implant head configured to expand, inside the bone, from a collapsed state to an expanded state. The apparatus may include an intramedullary rod defining a central longitudinal rod axis. The intramedullary rod may include a guide segment configured to guide the implant head into the bone and support the implant tail. The intramedullary rod may include an elongated extension member spaced radially apart from the central longitudinal axis. The extension member may be configured to provide clearance for the implant head as the implant head is advanced, in the collapsed state, into the bone. The extension member may be configured to provide clearance for the implant head in the expanded state.

Abstract: Apparatus and methods for repairing a bone. The apparatus may include a prosthesis. The prosthesis may have a first face. The first face may be shaped to conform to a native articular bone surface and define a perimeter. The prosthesis may have a second face. The second face may be shaped to conform to a bone surface prepared for receiving the prosthesis. The second face may define two or more screw-holes adjacent the perimeter. The prosthesis may define, other than the screw-holes, no anchor pass-through.

Abstract: Apparatus and methods for treating a spinal body having an interior. The method may include augmenting a height of the spinal body by radially expanding a first mesh cage in the interior. The method may include removing the first cage from the interior. The method may include supporting the spinal body in an elevated position by radially expanding a second mesh cage in the interior. The method may also include surgically enclosing the second cage in the interior.

Abstract: Apparatus and methods for delivery of an implant at a target site in an interior of a bone. The apparatus may include a plate. The plate may include a bottom surface complementing a surface contour of a bone. The plate may define first holes sized for receiving screws. The plate may define second holes sized for receiving fixation elements. The plate may define an opening. The opening may be sized for providing passage of the implant through the plate. When the bottom surface is seated complementarily against the surface contour, the first holes may point into an interior of the bone and into a volume occupied by the implant in the interior when the implant is positioned at a target site and radially expanded to form a mesh cage.