Patents by Inventor Jonathan Bromberg

Jonathan Bromberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Automated identification of cooling holes and toolpath generation
    Patent number: 12221897
    Abstract: A method of processing a part includes: identifying (2502) a location of at least one hole (62) disposed in the part using a computer-aided design (CAD) model of the part (36); aligning (2504) the part in a mounting system (56); 3D-scanning (2506) the part (36); detecting (2520) at least one boundary feature of the hole (36) based at least partially on at least one datum from 3D-scanning (2506) the part; and generating (2536) a first toolpath (92) based at least partially on the boundary feature.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: February 11, 2025
    Assignee: GE INFRASTRUCTURE TECHNOLOGY LLC
    Inventors: Rajesh Ramamurthy, Kevin George Harding, Jonathan Matthew Lomas, Vadim Bromberg
  • METHODS AND PLATFORMS FOR PROMOTING ANTIGEN-SPECIFIC TOLERANCE IN THE TREATMENT OF TYPE 1 DIABETES AND GRAFT REJECTION AND COMPOSITIONS RELATING THERETO
    Publication number: 20240245762
    Abstract: The present disclosure is directed to systems, compositions and methods for promoting immune tolerance to an antigen in a subject. Systems and methods provide for introducing directly into at least one lymph node(s) of the subject a therapeutically effective amount of a composition comprising an antigen associated with an autoimmune disease or disorder, in combination with a carrier comprising an immune modulatory agent such that an immune response to said antigen is inhibited or suppressed in the subject. The present disclosure is also directed to systems, compositions and methods for the treatment and/or prevention of autoimmune diseases and conditions, and in particular type 1 diabetes and graft rejection.
    Type: Application
    Filed: January 12, 2022
    Publication date: July 25, 2024
    Inventors: Christopher M. JEWELL, Joshua M. GAMMON, Lisa H. TOSTANOSKI, Jonathan BROMBERG
  • Inhibitors of LT?R-NF?B signaling pathways for treating inflammation and cancer
    Patent number: 11590202
    Abstract: The present invention provides compositions and methods for selective inhibition of the classical or non-classical LT?R-NF?B signaling pathway. In some embodiments, the compositions and methods of the present invention are useful for treating or preventing tissue graft rejection, inflammation, contact hypersensitivity, and cancer by decreasing cell motility.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: February 28, 2023
    Assignee: University of Maryland, Baltimore
    Inventors: Jonathan Bromberg, Wenji Piao, Yanbao Xiong
  • Compositions and Methods for Treating Inflammation and Cancer
    Publication number: 20200085912
    Abstract: The present invention provides compositions and methods for selective inhibition of the classical or non-classical LT?R-NF?B signaling pathway. In some embodiments, the compositions and methods of the present invention are useful for treating or preventing tissue graft rejection, inflammation, contact hypersensitivity, and cancer by decreasing cell motility.
    Type: Application
    Filed: April 11, 2018
    Publication date: March 19, 2020
    Inventors: Jonathan Bromberg, Wenji Piao, Yanbao Xiong