Patents by Inventor Jonathan Brostoff
Jonathan Brostoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7368137Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: GrantFiled: January 9, 2007Date of Patent: May 6, 2008Assignee: Phytopharm PLCInventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
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Patent number: 7341746Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.Type: GrantFiled: November 20, 2003Date of Patent: March 11, 2008Assignee: Phytotech LimitedInventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
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Publication number: 20070191290Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceuical compositions are also disclosed.Type: ApplicationFiled: January 9, 2007Publication date: August 16, 2007Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
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Patent number: 7166308Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: GrantFiled: October 21, 2003Date of Patent: January 23, 2007Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
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Patent number: 7125708Abstract: A novel probiotic strain termed Lactobacillus pentosus NCIMB 41114 is capable of preventing growth of pathogenic microorganisms in the GI tract. In particular, this bacterium inhibits Candida overgrowth, and can be employed to prevent and treat associated diseases, including IBS and thrush.Type: GrantFiled: October 11, 2002Date of Patent: October 24, 2006Assignee: University of Reading, School of Food BiosciencesInventors: Anthony G. Wynne, Glenn R. Gibson, Jonathan Brostoff
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Publication number: 20060182817Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: ApplicationFiled: July 17, 2004Publication date: August 17, 2006Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
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Publication number: 20050031601Abstract: A novel probiotic strain termed Lactobacillus pentosus NCIMB 41114 is capable of preventing growth of pathogenic microorganisms in the GI tract. In particular, this bacterium inhibits Candida overgrowth, and can be employed to prevent and treat associated diseases, including IBS and thrush.Type: ApplicationFiled: October 11, 2002Publication date: February 10, 2005Inventors: Anthony Wynne, Glenn Gibson, Jonathan Brostoff
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Patent number: 6812213Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: GrantFiled: February 15, 2002Date of Patent: November 2, 2004Assignee: Phytopharm, plcInventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
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Publication number: 20040101581Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.Type: ApplicationFiled: November 20, 2003Publication date: May 27, 2004Applicant: Phytotech LimitedInventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
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Publication number: 20040081709Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: ApplicationFiled: October 21, 2003Publication date: April 29, 2004Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
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Patent number: 6676975Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.Type: GrantFiled: February 14, 2002Date of Patent: January 13, 2004Assignee: Phytotech LimitedInventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
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Publication number: 20030118673Abstract: The invention discloses the use of smilagenin and anzurogenin D in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: ApplicationFiled: January 3, 2003Publication date: June 26, 2003Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
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Publication number: 20030032604Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: ApplicationFiled: August 26, 2002Publication date: February 13, 2003Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
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Publication number: 20020193317Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: ApplicationFiled: February 15, 2002Publication date: December 19, 2002Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
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Publication number: 20020192312Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.Type: ApplicationFiled: February 14, 2002Publication date: December 19, 2002Applicant: Phytotech LimitedInventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
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Patent number: 6399112Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.Type: GrantFiled: December 24, 1996Date of Patent: June 4, 2002Assignee: Phytotech LimitedInventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
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Publication number: 20010043955Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: ApplicationFiled: May 25, 2001Publication date: November 22, 2001Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
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Patent number: 6258386Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.Type: GrantFiled: July 28, 1999Date of Patent: July 10, 2001Assignee: Phytopharm PLCInventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang