Patents by Inventor Jonathan Brostoff

Jonathan Brostoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7368137
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: May 6, 2008
    Assignee: Phytopharm PLC
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Patent number: 7341746
    Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: March 11, 2008
    Assignee: Phytotech Limited
    Inventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
  • Publication number: 20070191290
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceuical compositions are also disclosed.
    Type: Application
    Filed: January 9, 2007
    Publication date: August 16, 2007
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Patent number: 7166308
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: January 23, 2007
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Patent number: 7125708
    Abstract: A novel probiotic strain termed Lactobacillus pentosus NCIMB 41114 is capable of preventing growth of pathogenic microorganisms in the GI tract. In particular, this bacterium inhibits Candida overgrowth, and can be employed to prevent and treat associated diseases, including IBS and thrush.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: October 24, 2006
    Assignee: University of Reading, School of Food Biosciences
    Inventors: Anthony G. Wynne, Glenn R. Gibson, Jonathan Brostoff
  • Publication number: 20060182817
    Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: July 17, 2004
    Publication date: August 17, 2006
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
  • Publication number: 20050031601
    Abstract: A novel probiotic strain termed Lactobacillus pentosus NCIMB 41114 is capable of preventing growth of pathogenic microorganisms in the GI tract. In particular, this bacterium inhibits Candida overgrowth, and can be employed to prevent and treat associated diseases, including IBS and thrush.
    Type: Application
    Filed: October 11, 2002
    Publication date: February 10, 2005
    Inventors: Anthony Wynne, Glenn Gibson, Jonathan Brostoff
  • Patent number: 6812213
    Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: November 2, 2004
    Assignee: Phytopharm, plc
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
  • Publication number: 20040101581
    Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.
    Type: Application
    Filed: November 20, 2003
    Publication date: May 27, 2004
    Applicant: Phytotech Limited
    Inventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
  • Publication number: 20040081709
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: October 21, 2003
    Publication date: April 29, 2004
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Patent number: 6676975
    Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: January 13, 2004
    Assignee: Phytotech Limited
    Inventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
  • Publication number: 20030118673
    Abstract: The invention discloses the use of smilagenin and anzurogenin D in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: January 3, 2003
    Publication date: June 26, 2003
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
  • Publication number: 20030032604
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: August 26, 2002
    Publication date: February 13, 2003
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Publication number: 20020193317
    Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: February 15, 2002
    Publication date: December 19, 2002
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
  • Publication number: 20020192312
    Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.
    Type: Application
    Filed: February 14, 2002
    Publication date: December 19, 2002
    Applicant: Phytotech Limited
    Inventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
  • Patent number: 6399112
    Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.
    Type: Grant
    Filed: December 24, 1996
    Date of Patent: June 4, 2002
    Assignee: Phytotech Limited
    Inventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
  • Publication number: 20010043955
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: May 25, 2001
    Publication date: November 22, 2001
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang
  • Patent number: 6258386
    Abstract: The invention discloses the use of a smilagenin in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: July 28, 1999
    Date of Patent: July 10, 2001
    Assignee: Phytopharm PLC
    Inventors: Zongqin Xia, Ian Rubin, Brian Whittle, Philip Gunning, Yaer Hu, Jonathan Brostoff, Weijun Wang