Patents by Inventor Jonathan C. Evans
Jonathan C. Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11275072Abstract: Effects of Oxygen on grease or another organic paste product can be evaluated with a modified version of the ASTM D942 test methodology for oxidation stability of lubricating greases or other organic paste products by employment of an oxidation pressure vessel, in which at least one of (A) a very small sample of the grease or other organic paste product is deployed for testing within the oxidation pressure vessel such that the sample has an enhanced surface area to mass ratio, and (B) a temperature other than about 99° C. is employed during the testing. In general, the testing is carried out under oxidation pressure conditions. The sample may be evaluated with respect to Oxygen uptake. Additional technique(s) directed to oxidation and/or other properties of the sample may be carried out before to after any Oxygen uptake evaluation, for example, FTIR analysis and/or ATR-FTIR analysis.Type: GrantFiled: April 5, 2017Date of Patent: March 15, 2022Assignee: TANNAS COMPANYInventors: Jonathan C. Evans, Theodore W. Selby, Marta Manning
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Patent number: 10914719Abstract: A significantly improved version of the ASTM D942 Test Method, with apparatus employable to effect the same, is provided. This is useful in measurement of grease oxidation.Type: GrantFiled: November 6, 2014Date of Patent: February 9, 2021Assignee: TANNAS COMPANYInventors: Theodore W. Selby, Jonathan C. Evans, Gregory C. Miiller, Calvin David Hugo, Sarah Nuss-Warren, Douglas J. Wirsing
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Patent number: 10823656Abstract: Instrumentation embraces an at least partially automated rotational tapered bearing simulator viscometer having electronic control and/or monitoring that includes task unit electronics, which includes a task unit electronics interface. With or without such electronics, the instrumentation may include a particular component configuration and/or employ at least one particular material. Further feature(s) may be extant.Type: GrantFiled: September 21, 2018Date of Patent: November 3, 2020Assignee: TANNAS COMPANYInventors: Sarah R. Nuss-Warren, Douglas J. Wirsing, Derrick D. Hilliker, Theodore W. Selby, Jonathan C. Evans, Michael T. Kelly, Robert Culver, Fernando Moreira Mendes
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Patent number: 10663449Abstract: Elevated temperature liquid testing apparatus and methodology in which a thin film of test liquid and a reactant/control gas are provided about the top of a depositor member that is surrounded by a special mantle, for example, a substantially cylindrically walled glass mantle. As an oxidative engine oil test, it may mimic turbocharger conditions of a modern internal combustion engine. For example, employing moist air, the apparatus can test a thin film of engine oil for oxidation deposits at a predetermined temperature, say, 285° C., 290° C., or cycled between 285° C. or 290° C. and 320° C. or 330° C.Type: GrantFiled: November 1, 2018Date of Patent: May 26, 2020Assignee: TANNAS COMPANYInventors: Jonathan C. Evans, Theodore W. Selby, Marta Manning, Gregory C. Miiller, William John VanBergen
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Patent number: 10625233Abstract: An active pharmaceutical ingredients (API) or related substance (RS) can be tested for stability by placing the API or RS in an instrument containing a pressure-controllable atmosphere, controlling the pressure of the atmosphere in the instrument for a predetermined time, and evaluating the API or RS for stability. Testing can be carried out also at predetermined temperature(s) and/or under the influence of gaseous trigger(s) and so forth. For instance, an API sample can be placed in a bomb test instrument/reactor, oxygen as a gaseous trigger can be introduced to contact the API sample under constant and/or ramped temperature(s) and elevated pressure(s) for predetermined time(s), and the API sample can be evaluated for stability. An insert carousel may hold a sample of API(s) and/or RS(s) and/or aliquot(s) of sample(s) of API(s) and/or RS(s) for insertion into the bomb test instrument/reactor.Type: GrantFiled: April 3, 2018Date of Patent: April 21, 2020Assignee: Tannas CompanyInventors: Jonathan C. Evans, Derrick D. Hilliker, Theodore W. Selby
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Patent number: 10422783Abstract: Apparatus includes a pivotable, cradling framework that can hold a rotatable bomb instrument, which can include a hollow cylinder and a grease rack. This may be employed to effect a significantly improved version of the ASTM D942 Test Method. The same is useful in measurement of grease oxidation.Type: GrantFiled: October 17, 2018Date of Patent: September 24, 2019Assignee: TANNAS COMPANYInventors: Theodore W. Selby, Jonathan C. Evans, Gregory C. Miiller, Calvin David Hugo, Sarah R. Nuss-Warren, Douglas J. Wirsing
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Patent number: 10302619Abstract: Grease wear test device includes a body in a form of a collar having an outer surface, a first side and an opposing second side, which are open to form a hollow, open channel through the body, which has a center axis, into which opposing vee blocks can be inserted; and perpendicular to the center axis, a pair of opposing holes through and open to the outer surface of the body and the cylindrical inside wall, through which a cylindrical test journal (falex pin) can be inserted for contact in general with opposing vee-shaped channels of the inserted, opposing vee blocks, and for rotation during testing. The device can be used to modify a falex pin and vee block device, to receive and contain a small sample of grease or another organic paste product for testing such as a modified version of an ASTM D2670 test method for measuring wear properties of fluid lubricants (falex pin and vee block method).Type: GrantFiled: April 7, 2017Date of Patent: May 28, 2019Assignee: TANNAS COMPANYInventors: Jonathan C. Evans, Theodore W. Selby, Marta Manning, Derrick D. Hilliker, Michael A. Habitz
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Publication number: 20190145948Abstract: Elevated temperature liquid testing apparatus and methodology in which a thin film of test liquid and a reactant/control gas are provided about the top of a depositor member that is surrounded by a special mantle, for example, a substantially cylindrically walled glass mantle. As an oxidative engine oil test, it may mimic turbocharger conditions of a modern internal combustion engine. For example, employing moist air, the apparatus can test a thin film of engine oil for oxidation deposits at a predetermined temperature, say, 285° C., 290° C., or cycled between 285° C. or 290° C. and 320° C. or 330° C.Type: ApplicationFiled: November 1, 2018Publication date: May 16, 2019Applicant: Tannas CompanyInventors: Jonathan C. Evans, Theodore W. Selby, Marta Manning, Gregory C. Miiller, William John VanBergen
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Publication number: 20190064137Abstract: Apparatus includes a pivotable, cradling framework that can hold a rotatable bomb instrument, which can include a hollow cylinder and a grease rack. This may be employed to effect a significantly improved version of the ASTM D942 Test Method. The same is useful in measurement of grease oxidation.Type: ApplicationFiled: October 17, 2018Publication date: February 28, 2019Applicant: Tannas CompanyInventors: Theodore W. Selby, Jonathan C. Evans, Gregory C. Miiller, Calvin David Hugo, Sarah R. Nuss-Warren, Douglas J. Wirsing
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Publication number: 20180326385Abstract: An active pharmaceutical ingredients (API) or related substance (RS) can be tested for stability by placing the API or RS in an instrument containing a pressure-controllable atmosphere, controlling the pressure of the atmosphere in the instrument for a predetermined time, and evaluating the API or RS for stability. Testing can be carried out also at predetermined temperature(s) and/or under the influence of gaseous trigger(s) and so forth. For instance, an API sample can be placed in a bomb test instrument/reactor, oxygen as a gaseous trigger can be introduced to contact the API sample under constant and/or ramped temperature(s) and elevated pressure(s) for predetermined time(s), and the API sample can be evaluated for stability. An insert carousel may hold a sample of API(s) and/or RS(s) and/or aliquot(s) of sample(s) of API(s) and/or RS(s) for insertion into the bomb test instrument/reactor.Type: ApplicationFiled: April 3, 2018Publication date: November 15, 2018Applicant: Tannas CompanyInventors: Jonathan C. Evans, Derrick D. Hilliker, Theodore W. Selby
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Publication number: 20180003692Abstract: Grease wear test device includes a body in a form of a collar having an outer surface, a first side and an opposing second side, which are open to form a hollow, open channel through the body, which has a center axis, into which opposing vee blocks can be inserted; and perpendicular to the center axis, a pair of opposing holes through and open to the outer surface of the body and the cylindrical inside wall, through which a cylindrical test journal (falex pin) can be inserted for contact in general with opposing vee-shaped channels of the inserted, opposing vee blocks, and for rotation during testing. The device can be used to modify a falex pin and vee block device, to receive and contain a small sample of grease or another organic paste product for testing such as a modified version of an ASTM D2670 test method for measuring wear properties of fluid lubricants (falex pin and vee block method).Type: ApplicationFiled: April 7, 2017Publication date: January 4, 2018Applicant: Tannas CompanyInventors: Jonathan C. Evans, Theodore W. Selby, Marta Manning, Derrick D. Hilliker, Michael A. Habitz
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Publication number: 20170284994Abstract: Effects of Oxygen on grease or another organic paste product can be evaluated with a modified version of the ASTM D942 test methodology for oxidation stability of lubricating greases or other organic paste products by employment of an oxidation pressure vessel, in which at least one of (A) a very small sample of the grease or other organic paste product is deployed for testing within the oxidation pressure vessel such that the sample has an enhanced surface area to mass ratio, and (B) a temperature other than about 99° C. is employed during the testing. In general, the testing is carried out under oxidation pressure conditions. The sample may be evaluated with respect to Oxygen uptake. Additional technique(s) directed to oxidation and/or other properties of the sample may be carried out before to after any Oxygen uptake evaluation, for example, FTIR analysis and/or ATR-FTIR analysis.Type: ApplicationFiled: April 5, 2017Publication date: October 5, 2017Applicant: Tannas CompanyInventors: Jonathan C. Evans, Theodore W. Selby, Marta Manning
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Publication number: 20170205355Abstract: A significantly improved version of the ASTM D942 Test Method, with apparatus employable to effect the same, is provided. This is useful in measurement of grease oxidation.Type: ApplicationFiled: November 6, 2014Publication date: July 20, 2017Applicant: Tannas CompanyInventors: Theodore W. Selby, Jonathan C. Evans, Gregory C. Miiller, Calvin David Hugo, Sarah Nuss-Warren, Douglas J. Wirsing
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Publication number: 20160074328Abstract: The present invention is a method for preparing micron-sized or submicron-sized drug particles comprising contacting a solution comprising a poorly water soluble drug substance and at least one freezable organic solvent with a cold surface so as to freeze the solution; and removing the organic solvent. The resulting particles are also disclosed, as are several embodiments of an apparatus that can be used in performing the method of the present invention.Type: ApplicationFiled: September 22, 2015Publication date: March 17, 2016Inventors: Brian D. SCHERZER, Jonathan C. EVANS, James E. HITT
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Patent number: 9175906Abstract: The present invention is a method for preparing micron-sized or submicron-sized drug particles comprising contacting a solution comprising a poorly water soluble drug substance and at least one freezable organic solvent with a cold surface so as to freeze the solution; and removing the organic solvent. The resulting particles are also disclosed, as are several embodiments of an apparatus that can be used in performing the method of the present invention.Type: GrantFiled: August 12, 2003Date of Patent: November 3, 2015Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Brian D. Scherzer, Jonathan C. Evans, James E. Hitt
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Publication number: 20040210061Abstract: The present invention provides various processes for the preparation of (R)-&agr;-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol.Type: ApplicationFiled: May 4, 2004Publication date: October 21, 2004Applicants: Aventis Pharmaceuticals Inc., Aventis Pharma Deutschland GmbHInventors: Thomas Heinz Eduard Hilpert, Hans-Wolfram Flemming, Sandra K. Stolz-Dunn, Jonathan C. Evans, Ian A. Tomlinson
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Publication number: 20040137070Abstract: The present invention is a method for preparing micron-sized or submicron-sized drug particles comprising contacting a solution comprising a poorly water soluble drug substance and at least one freezable organic solvent with a cold surface so as to freeze the solution; and removing the organic solvent. The resulting particles are also disclosed, as are several embodiments of an apparatus that can be used in performing the method of the present invention.Type: ApplicationFiled: August 12, 2003Publication date: July 15, 2004Inventors: Brian D. Scherzer, Jonathan C. Evans, James E. Hitt
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Patent number: 6713627Abstract: The present invention provides various processes for the preparation of (R)-&agr;-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol.Type: GrantFiled: January 11, 2002Date of Patent: March 30, 2004Assignee: Aventis Pharmaceuticals Inc.Inventors: Edward D. Daugs, Jonathan C. Evans, Hans-Wolfram Flemming, Thomas Heinz Eduard Hilpert, Johannes Nicolaas Koek, Frederick M. Laskovics, Sandra K. Stolz-Dunn, Ian A. Tomlinson
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Publication number: 20030133987Abstract: A method for producing micron-sized or submicron-sized drugs is disclosed, which comprises preparing a template emulsion comprising water and a templating agent; preparing a drug-containing mixture comprising a drug substance; and combining the template emulsion with the drug-containing mixture to form a template emulsion loaded with drug particles. Drug particles prepared from this process are also disclosed. The resulting drug particles demonstrate faster dissolution rates and enhanced bioavailability as compared to unprocessed drug particles and particles prepared using other processes.Type: ApplicationFiled: January 10, 2003Publication date: July 17, 2003Inventors: Sonke Svenson, Chris J. Tucker, Steve Lubetkin, Jonathan C. Evans, Steve S. Rosenberg
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Publication number: 20030049323Abstract: A process for preparing crystalline particles of a drug substance is disclosed, said process comprising recirculating an anti-solvent through a mixing zone, dissolving the drug substance in a solvent to form a solution, adding the solution to the mixing zone to form a particle slurry in the anti-solvent, and recirculating at least a portion of the particle slurry back through the mixing zone. Particles produced from the process are also disclosed. The present invention has the ability to be operated in a continuous fashion, resulting in a more efficient process and a more uniform product. The present invention has the additional advantage of having the ability to operate at a relatively low solvent ratio, thereby increasing the drug to excipient ratio.Type: ApplicationFiled: August 27, 2002Publication date: March 13, 2003Inventors: James E. Hitt, Christopher J. Tucker, Jonathan C. Evans, Cathy A. Curtis, Sonke Svenson