Patents by Inventor Jonathan C. Tripp

Jonathan C. Tripp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Copper catalyzed cycloaddition of organic azides and 1-haloalkynes
    Patent number: 8927736
    Abstract: This invention provides a method for preparing a 1,2,3-triazole compound comprising contacting an organic azide with a 2-substituted-1-haloalkyne, in the presence of a copper catalyst and a copper-coordinating ligand (preferably a tertiary amine) in a liquid reaction medium, thereby forming a 1,4,5-substituted-1,2,3-triazole compound including a halo substituent at the 5-position of the triazole, the organic portion of the organic azide at the 1-position of the triazole, and the substituent of the 1-iodoalkyne at the 4-position of the triazole. A method for preparing 1-iodoalkynes is also provided.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: January 6, 2015
    Assignee: The Scripps Research Institute
    Inventors: Jason E. Hein, Jonathan C. Tripp, Larissa Krasnova, K. Barry Sharpless, Valery V. Fokin
  • COPPER CATALYZED CYCLOADDITION OF ORGANIC AZIDES AND 1-HALOALKYNES
    Publication number: 20120142935
    Abstract: This invention provides a method for preparing a 1,2,3-triazole compound comprising contacting an organic azide with a 2-substituted-1-haloalkyne, in the presence of a copper catalyst and a copper-coordinating ligand (preferably a tertiary amine) in a liquid reaction medium, thereby forming a 1,4,5-substituted-1,2,3-triazole compound including a halo substituent at the 5-position of the triazole, the organic portion of the organic azide at the 1-position of the triazole, and the substituent of the 1-iodoalkyne at the 4-position of the triazole. A method for preparing 1-iodoalkynes is also provided.
    Type: Application
    Filed: August 11, 2010
    Publication date: June 7, 2012
    Inventors: Jason E. Hein, Jonathan C. Tripp, Larissa Krasnova, K.Barry Sharpless, Valery V. Fokin