Patents by Inventor Jonathan Claypool

Jonathan Claypool has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220186207
    Abstract: Solutions, reagents, and methods for nucleic acid purification. In certain aspects, cationic surfactant and, optionally, an anionic surfactant solutions are provided which can be used for phase separation and capture of nucleic acids, such as plasmid or genomic DNA, to a solid phase carrier, such as a mineral matrix.
    Type: Application
    Filed: December 17, 2021
    Publication date: June 16, 2022
    Inventors: Ryan KEMP, Jonathan A. CLAYPOOL, Marc E. VAN EDEN, Xi-Yu JIA
  • Patent number: 11236325
    Abstract: Solutions, reagents, and methods for nucleic acid purification. In certain aspects, cationic surfactant and, optionally, an anionic surfactant solutions are provided which can be used for phase separation and capture of nucleic acids, such as plasmid or genomic DNA, to a solid phase carrier, such as a mineral matrix.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: February 1, 2022
    Assignee: ZYMO RESEARCH CORPORATION
    Inventors: Ryan Kemp, Jonathan A. Claypool, Marc E. Van Eden, Xi-Yu Jia
  • Publication number: 20180371450
    Abstract: Solutions, reagents, and methods for nucleic acid purification. In certain aspects, cationic surfactant and, optionally, an anionic surfactant solutions are provided which can be used for phase separation and capture of nucleic acids, such as plasmid or genomic DNA, to a solid phase carrier, such as a mineral matrix.
    Type: Application
    Filed: April 25, 2018
    Publication date: December 27, 2018
    Inventors: Ryan KEMP, Jonathan A. CLAYPOOL, Marc E. VAN EDEN, Xi-Yu JIA
  • Publication number: 20150225713
    Abstract: Solutions, reagents, and methods for nucleic acid purification. In certain aspects, cationic surfactant and, optionally, an anionic surfactant solutions are provided which can be used for phase separation and capture of nucleic acids, such as plasmid or genomic DNA, to a solid phase carrier, such as a mineral matrix.
    Type: Application
    Filed: February 10, 2015
    Publication date: August 13, 2015
    Inventors: Ryan KEMP, Jonathan A. CLAYPOOL, Marc E. VAN EDEN, Xi-Yu JIA
  • Publication number: 20060040393
    Abstract: The present invention relates to the simple, gentle, and efficient extraction of biological material from Escherichia coli (E. coli). The use of E. coli in research laboratories depends on the ability to prepare lysates to isolate the desired products under investigation. The present invention includes methods and engineered E. coli strains that are capable of rapid controlled lysis or herein “autolysis”. The XJa strains were made from JM109 and the XJb strains from BL21 by insertion of the ? R or (? RS) lytic endolysin gene to replace the tightly regulated araB gene. Thus, arabinose becomes a non-metabolizable inducer and the controlled autolysis phenotype is induced by the PBAD promoter by the presence of saturating arabinose. Upon induction of the bacteriophage ?R endolysin, the E. coli remains intact but is efficiently lysed after one freeze-thaw cycle. The present invention is usable with many different buffer systems and is flexible in this regard.
    Type: Application
    Filed: August 16, 2005
    Publication date: February 23, 2006
    Inventors: Xiyu Jia, Jan kostal, Jonathan Claypool