Abstract: The present invention relates to a cell surface molecule, designated cadherin-like asymmetry protein-5 (“CLASP-5”). In particular, it relates to CLASP-5 polynucleotides, polypeptides, fusion proteins, and antibodies. The invention also relates to methods of modulating an immune response by interfering with CLASP-5 function.

Abstract: The present invention relates to a cell surface molecule, designated cadherin-like asymmetry protein-3 (“CLASP-3”). In particular, it relates to CLASP-3 polynucleotides, polypeptides, fusion proteins, and antibodies. The invention also relates to methods of modulating an immune response by interfering with CLASP-3 function.

Abstract: The present invention relates to a cell surface molecule, designated cadherin-like asymmetry protein-4 (“CLASP-4”). In particular, it relates to CLASP-4 polynucleotides, polypeptides, fusion proteins, and antibodies. The invention also relates to methods of modulating an immune response by interfering with CLASP-4 function.

Abstract: In accordance with the present invention, an address mapper is provided between the CPU running a MS-DOS application program and a frame buffer, so as to allow the frame buffer to be mapped into the CPU address space expected by a MS-DOS application program. A write operation by the MS-DOS application program into the CPU's display address space is translated by the address mapper to be performed in the address space of the frame buffer, providing to the user the appearance as if the frame buffer is part of the CPU's address space ("Virtual MS-DOS display"). This frame buffer may have an address space larger than that used by the MS-DOS application program for writing to the display. This additional space can be allocated to other processes, which are each protected from inadvertently reading or writing into another process' allocated memory space.

Abstract: An improved optical fiber is disclosed having particular application for use in a fiber optic communication system. The optical fiber includes an optically transparent core which is doped with a lasing material of the same type used in the diode laser transmitter of the particular communication system. The lasing dopant has the greatest density in the center of the core, and is diffused outward into an optically tranparent cladding surrounding the core which has an index of refraction lower than an index of refraction of the core. The optical fiber is "pumped" such that the lasing dopant within the fiber lases at a desired wavelength and provides gain for the original optical signal provided by the diode laser. The lasing of the dopant material within the fiber results in continuous optical gain along the length of the fiber and avoids the need for repeaters in the fiber optic communication system.