Patents by Inventor Jonathan D. Walton

Jonathan D. Walton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9932571
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
    Type: Grant
    Filed: February 20, 2017
    Date of Patent: April 3, 2018
    Assignee: Board of Trustees of Michigan State University
    Inventors: Heather E. Hallen-Adams, John S. Scott-Craig, Jonathan D. Walton, Hong Luo
  • Publication number: 20170275608
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
    Type: Application
    Filed: February 20, 2017
    Publication date: September 28, 2017
    Inventors: Heather E. Hallen-Adams, John S. Scott-Craig, Jonathan D. Walton, Hong Luo
  • Patent number: 9598686
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: March 21, 2017
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Heather E. Hallen-Adams, John S. Scott-Craig, Jonathan D. Walton, Hong Luo
  • Patent number: 9518097
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.
    Type: Grant
    Filed: November 10, 2008
    Date of Patent: December 13, 2016
    Assignee: Board of Trustees of Michigan State University
    Inventors: Heather E. Hallen, Jonathan D. Walton, Hong Luo, John S. Scott-Craig
  • Publication number: 20160281075
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
    Type: Application
    Filed: November 5, 2015
    Publication date: September 29, 2016
    Inventors: Heather E. Hallen-Adams, John S. Scott-Craig, Jonathan D. Walton, Hong Luo
  • Patent number: 9404136
    Abstract: The invention relates to increasing the availability of fermentable sugars from plant biomass, such as glucose and xylose. As described herein, ?-xylosidases can be employed with cellulases to enhance biomass conversion into free, fermentable sugar residues.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: August 2, 2016
    Assignee: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventors: Jonathan D. Walton, John S. Scott-Craig, Melissa Borrusch
  • Patent number: 9273100
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: March 1, 2016
    Assignee: Board of Trustees of Michigan State University
    Inventors: Heather E. Hallen-Adams, John S. Scott-Craig, Jonathan D. Walton, Hong Luo
  • Publication number: 20140004572
    Abstract: The invention relates to increasing the availability of fermentable sugars from plant biomass, such as glucose and xylose. As described herein, ?-xylosidases can be employed with cellulases to enhance biomass conversion into free, fermentable sugar residues.
    Type: Application
    Filed: March 8, 2013
    Publication date: January 2, 2014
    Applicant: Board of Trustees of Michigan State University
    Inventors: Jonathan D. Walton, John S. Scott-Craig, Melissa Borrusch
  • Publication number: 20120276588
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
    Type: Application
    Filed: January 31, 2012
    Publication date: November 1, 2012
    Inventors: Heather E. Hallen-Adams, John S. Scott-Craig, Jonathan D. Walton, Hong Luo
  • Publication number: 20100267019
    Abstract: The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptide toxins and toxin production in mushrooms. In particular, the present invention relates to using genes and proteins from Amanita species encoding Amanita peptides, specifically relating to amatoxins and phallotoxins. In a preferred embodiment, the present invention also relates to methods for detecting Amanita peptide toxin genes for identifying Amanita peptide-producing mushrooms and for diagnosing suspected cases of mushroom poisoning. Further, the present inventions relate to providing kits for diagnosing and monitoring suspected cases of mushroom poisoning in patients.
    Type: Application
    Filed: November 10, 2008
    Publication date: October 21, 2010
    Inventors: Heather E. Hallen, John S. Scott-Craig, Jonathan D. Walton, Hong Luo
  • Patent number: 5973229
    Abstract: The cDNA encoding safener binding protein (SafBP), also referred to as SBP1, is set forth in FIG. 5 and SEQ ID No. 1. The deduced amino acid sequence is provided in FIG. 5 and SEQ ID No. 2. Methods of making and using SBP1 and SafBP to alter a plant's sensitivity to certain herbicides or a plant's responsiveness to certain safeners are also provided, as well as expression vectors, transgenic plants or other organisms transfected with said vectors and seeds from said plants.
    Type: Grant
    Filed: April 25, 1997
    Date of Patent: October 26, 1999
    Assignee: Board of Trustees Operating Michigan State University
    Inventors: Jonathan D. Walton, John S. Scott-Craig