Patents by Inventor Jonathan D. Wren

Jonathan D. Wren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhancing progenitor cell numbers
    Patent number: 9950037
    Abstract: Therapies using IL-18 alone or in combination with IL-7 for rebuilding weakened immune systems by increasing progenitor cell yields from bone marrow stem cells and/or increasing stem cell engraftment in bone marrow.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: April 24, 2018
    Assignees: The Board of Regents of the University of Oklahoma, Oklahoma Medical Research Foundation
    Inventors: Tracy Kent Teague, Jonathan D. Wren, Siva Kumar Gandhapudi, Julie Harris Marino, Chibing Tan, Ashlee Allison Rempel, Charles Justin Van De Wiele
  • ENHANCING PROGENITOR CELL NUMBERS
    Publication number: 20160143997
    Abstract: Therapies using IL-18 alone or in combination with IL-7 for rebuilding weakened immune systems by increasing progenitor cell yields from bone marrow stem cells and/or increasing stem cell engraftment in bone marrow.
    Type: Application
    Filed: November 20, 2015
    Publication date: May 26, 2016
    Inventors: Tracy Kent Teague, Jonathan D. Wren, Siva Kumar, Julie Harris Marino, Chibing Tan, Ashlee Allison Rempel, Charles Justin Van De Wiele
  • Computer program products, systems and methods for information discovery and relational analyses
    Publication number: 20040093331
    Abstract: The present invention is a system, method for accessing domains of information to identify heretofore unknown relationships between disparate sources of data to seek and obtain knowledge, the invention includes a source of data with one or more domains of information, an Object-Relationship Database for integrating objects from one or more domains of information and a knowledge discovery engine where relationships between two or more objects are identified, retrieved, grouped, ranked, filtered and numerically evaluated.
    Type: Application
    Filed: September 19, 2003
    Publication date: May 13, 2004
    Applicant: Board of Regents, University of Texas System
    Inventors: Harold R. Garner, Jonathan D. Wren
  • Polymorphic repeats in human genes
    Patent number: 6472154
    Abstract: The invention provides computational methods and compositions for identifying polymorphic repeats in genes. Candidate polymorphic repeats are identified by detecting tandem repeats in a target coding sequence, scoring the repeats for polymorphic probability, and generating a dataset correlating the repeats with polymorphic probability. Actual polymorphic repeat are identified by further detecting the candidate polymorphic repeat in each of a population of different coding sequences, and determining whether the candidate polymorphic repeat is polymorphic in the population. Computationally derived polymorphic repeats are validated with phenotypic variations and these correlates are used to detect the presence or absence of such phenotypic variation in test genes. Variances at polymorphic repeats are identified by detecting in a test gene or coding region the presence or absence of variance at a disclosed unconventional polymorphic repeat.
    Type: Grant
    Filed: December 31, 1999
    Date of Patent: October 29, 2002
    Assignee: Board of Regents, The University of Texas System
    Inventors: Harold R. Garner, Jonathan D. Wren, John D. Minna, John W. Fondon, III