Patents by Inventor Jonathan David Gass

Jonathan David Gass has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination enzyme therapy for digestion of dietary gluten
    Patent number: 8778338
    Abstract: A combination enzyme product consisting of a glutamine specific endoprotease and a prolyl endopeptidase is provided. Both enzymes are active and stable in the stomach and can therefore be administered as lyophilized powders or simple capsules/tablets. A ratio of the two enzymes is used to maximize their synergy.
    Type: Grant
    Filed: March 14, 2008
    Date of Patent: July 15, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Jonathan David Gass, Chaitan Khosla, Michael Bethune, Matthew John Siegel
  • Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides
    Patent number: 8119125
    Abstract: Methods and compositions are provided for stabilizing polypeptides for oral administration, particularly where enteric delivery is desirable. By administering the polypeptides with a bile sequestering agent, the stability of the polypeptide can be increased. Pharmaceutical formulations for this purpose are provided.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: February 21, 2012
    Assignee: Alvine Pharmaceuticals, Inc.
    Inventor: Jonathan David Gass
  • Combination Enzyme Therapy for Digestion of Dietary Gluten
    Publication number: 20100092451
    Abstract: A combination enzyme product consisting of a glutamine specific endoprotease and a prolyl endopeptidase is provided. Both enzymes are active and stable in the stomach and can therefore be administered as lyophilized powders or simple capsules/tablets. A ratio of the two enzymes is used to maximize their synergy.
    Type: Application
    Filed: March 14, 2008
    Publication date: April 15, 2010
    Inventors: Jonathan David Gass, Chaitan Khosla, Michael Bethune, Matthew John Siegel
  • Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis
    Patent number: 7628985
    Abstract: Pharmaceutical formulations of glutenase enzymes are provided. The enzymes find particular use in the treatment of a Celiac or dermatitis herpetiformis patient.
    Type: Grant
    Filed: February 23, 2005
    Date of Patent: December 8, 2009
    Assignees: The Board of Regents of the Leland Stanford Junior University, Alvine Pharmaceuticals, Inc.
    Inventors: Lu Shan, Michael Thomas Bethune, Chaitan Khosla, Jonathan David Gass
  • Compositions and Methods for Enhanced Gastrointestinal Stability of Oligopeptides and Polypeptides
    Publication number: 20080311161
    Abstract: Methods and compositions are provided for stabilizing polypeptides for oral administration, particularly where enteric delivery is desirable. By administering the polypeptides with a bile sequestering agent, the stability of the polypeptide can be increased. Pharmaceutical formulations for this purpose are provided.
    Type: Application
    Filed: October 11, 2006
    Publication date: December 18, 2008
    Inventor: Jonathan David Gass
  • Therapeutic Enzyme Formulations And Uses Thereof
    Publication number: 20080193436
    Abstract: Pharmaceutical formulations of glutenase enzymes are provided. The enzymes find particular use in the treatment of a Celiac or dermatitis herpetiformis patient.
    Type: Application
    Filed: February 23, 2005
    Publication date: August 14, 2008
    Inventors: Lu Shan, Michael Bethune, Chaitan Khosla, Jonathan David Gass