Patents by Inventor Jonathan David Tuckwell
Jonathan David Tuckwell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10493222Abstract: Methods of fabricating and operating dry powder inhalers that include dose disks and airway channel disks with sealant layers, the airway channel disks forming radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers.Type: GrantFiled: February 6, 2017Date of Patent: December 3, 2019Assignee: Oriel Therapeutics, Inc.Inventors: Rachel Striebig, Matthew Allen, Thomas W. Ruckdeschel, Charles A. Buckner, III, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Patent number: 9795749Abstract: A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.Type: GrantFiled: February 12, 2015Date of Patent: October 24, 2017Assignee: Oriel Therapeutics, Inc.Inventors: Gerald A. Thoe, James G. Skakoon, David A. Schuelke, Thomas W. Ruckdeschel, David Harris, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Publication number: 20170143916Abstract: Methods of fabricating and operating dry powder inhalers that include dose disks and airway channel disks with sealant layers, the airway channel disks forming radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers.Type: ApplicationFiled: February 6, 2017Publication date: May 25, 2017Inventors: Rachel Striebig, Matthew Allen, Thomas W. Ruckdeschel, Charles A. Buckner, III, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Patent number: 9597465Abstract: Methods of fabricating and operating dry powder inhalers that include dose disks and airway channel disks with sealant layers, the airway channel disks forming radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers.Type: GrantFiled: January 24, 2014Date of Patent: March 21, 2017Assignee: Oriel Therapeutics, Inc.Inventors: Rachel Striebig, Matthew Allen, Thomas W. Ruckdeschel, Charles A. Buckner, III, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Patent number: 9522098Abstract: A reconstitution device having an opening surrounded by a neck, and a cap including a first end, a second end, and an inner bore having a central aperture. A stopper is positioned in the opening of the neck and includes a portion capable of being perforated. A plunger is located at the second end of the cap, is configured to slide along the inner bore of the cap, and includes a shaft extending downwardly in a direction towards the stopper and having a pointed end for piercing the stopper. A locking mechanism is located in the cap and includes an aperture. The locking mechanism is configured such that when the plunger is pushed downwardly the shaft is allowed to pass through the aperture, but when the plunger is pulled upwardly the second aperture changes shape such that the shaft cannot freely pass through the aperture.Type: GrantFiled: September 19, 2013Date of Patent: December 20, 2016Assignee: Bayer Healthcare, LLCInventors: Jonathan David Tuckwell, Robert Dyer, Robert Owen Kivlin, John Paul Palmer-Felgate, Matthew Burgess Avery, Kevin George Skinner, Chris Kadamus, Lee Wood, Peter Schwan, Ben Arlett
-
Publication number: 20150157812Abstract: A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.Type: ApplicationFiled: February 12, 2015Publication date: June 11, 2015Inventors: Gerald A. Thoe, James G. Skakoon, David A. Schuelke, Thomas W. Ruckdeschel, David Harris, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Patent number: 8985103Abstract: A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.Type: GrantFiled: January 18, 2013Date of Patent: March 24, 2015Assignee: Oriel Therapeutics, Inc.Inventors: Gerald A. Thoe, James G. Skakoon, David A. Schuelke, Thomas W. Ruckdeschel, David Harris, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Publication number: 20140166511Abstract: A reconstitution device having an opening surrounded by a neck, and a cap including a first end, a second end, and an inner bore having a central aperture. A stopper is positioned in the opening of the neck and includes a portion capable of being perforated. A plunger is located at the second end of the cap, is configured to slide along the inner bore of the cap, and includes a shaft extending downwardly in a direction towards the stopper and having a pointed end for piercing the stopper. A locking mechanism is located in the cap and includes an aperture. The locking mechanism is configured such that when the plunger is pushed downwardly the shaft is allowed to pass through the aperture, but when the plunger is pulled upwardly the second aperture changes shape such that the shaft cannot freely pass through the aperture.Type: ApplicationFiled: September 19, 2013Publication date: June 19, 2014Inventors: Jonathan David Tuckwell, Robert Dyer, Robert Owen Kivlin, John Paul Palmer-Felgate, Matthew Burgess Avery, Kevin George Skinner, Chris Kadamus, Lee Wood, Peter Schwan, Ben Arlett
-
Publication number: 20140137864Abstract: Methods of fabricating and operating dry powder inhalers that include dose disks and airway channel disks with sealant layers, the airway channel disks forming radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers.Type: ApplicationFiled: January 24, 2014Publication date: May 22, 2014Inventors: Rachel Striebig, Matthew Allen, Thomas W. Ruckdeschel, Charles A. Buckner, III, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Patent number: 8671938Abstract: Dry powder inhalers include radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers.Type: GrantFiled: January 7, 2013Date of Patent: March 18, 2014Assignee: Oriel Therapeutics, Inc.Inventors: Rachel Striebig, Matthew Allen, Thomas W. Ruckdeschel, Charles A. Buckner, III, David Harris, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Patent number: 8646446Abstract: Dry powder inhalers with rotatable piercing mechanisms facilitate the use of dose container assemblies having dose containers arranged in concentric rows. A piercing mechanism is operably associated with the dose container assembly and is configured to pierce sealants that seal a dose container. The piercing mechanism is rotatable such that it can serially alternate between the two rows of dose containers. The piercing mechanism includes a rotatable drum, an elongate piercing member, and a biasing member operably associated with the piercing member. The rotatable drum has an open end, an opposite closed end, and a cylindrical wall that extends from the closed end and terminates at the open end. The closed end includes an aperture formed therein in a location adjacent to the wall. The elongate piercing member is extended and retracted through the aperture to pierce the sealants of a dose container.Type: GrantFiled: September 25, 2009Date of Patent: February 11, 2014Assignee: Oriel Therapeutics, Inc.Inventors: Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell, Greg Beard, David Harris
-
Patent number: 8562582Abstract: A reconstitution device for storing a first component of a pharmaceutical preparation includes a receptacle, a cap having a first end secured to the receptacle, a second end, and an inner bore having a central aperture. The device further includes a stopper located between the receptacle and the cap, the stopper including a portion capable of being perforated. The device also includes a plunger secured to the second end of the cap, a locking mechanism located in the cap, and an actuating mechanism. The actuating mechanism may prevent the device from inadvertent activation.Type: GrantFiled: May 24, 2007Date of Patent: October 22, 2013Assignee: Bayer Healthcare LLCInventors: Jonathan David Tuckwell, Robert Dyer, Robert Owen Kivlin, Matthew Burgess Avery, Kevin George Skinner, Peter Schwan, John Paul Palmer-Felgate, Chris Kadamus, Lee Wood, Ben Arlett
-
Patent number: 8550071Abstract: Dry powder inhalers include radially-extending discrete, typically dose-specific, airway channels serially forming a portion of the inhalation pathway to deliver dry powder to a user using the inhalers.Type: GrantFiled: September 25, 2009Date of Patent: October 8, 2013Assignee: Oriel Therapeutics, Inc.Inventors: Rachel Striebig, Matthew Allen, Thomas W. Ruckdeschel, Charles A. Buckner, III, David Harris, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Patent number: 8381721Abstract: A dry powder inhaler includes a dose container assembly having a dose container disk with opposing upper and lower surfaces, a first row of circumferentially spaced apart dose containers at a first radius and a second row of circumferentially spaced apart dose containers at a second radius. The dose containers have dry powder therein and are sealed via a first flexible sealant over apertures in the upper surface and a second flexible sealant over apertures in the lower surface. A piercing mechanism includes two reciprocating piercers that serially alternate between the two rows of dose containers in the dose container disk. A rotatable ramp disk includes first and second sets of circumferentially spaced-apart ramp elements in staggered, concentric relationship that are configured to move the first and second piercing members between retracted and extended positions.Type: GrantFiled: September 25, 2009Date of Patent: February 26, 2013Assignee: Oriel Therapeutics, Inc.Inventors: Gerald A. Thoe, James G. Skakoon, David A. Schuelke, Thomas W. Ruckdeschel, David Harris, Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell
-
Publication number: 20110186047Abstract: Dry powder inhalers with rotatable piercing mechanisms facilitate the use of dose container assemblies having dose containers arranged in concentric rows. A piercing mechanism is operably associated with the dose container assembly and is configured to pierce sealants that seal a dose container. The piercing mechanism is rotatable such that it can serially alternate between the two rows of dose containers. The piercing mechanism includes a rotatable drum, an elongate piercing member, and a biasing member operably associated with the piercing member. The rotatable drum has an open end, an opposite closed end, and a cylindrical wall that extends from the closed end and terminates at the open end. The closed end includes an aperture formed therein in a location adjacent to the wall. The elongate piercing member is extended and retracted through the aperture to pierce the sealants of a dose container.Type: ApplicationFiled: September 25, 2009Publication date: August 4, 2011Inventors: Scott Alexander Lewis, Andrew Murray Gow, Jonathan David Tuckwell, Greg Beard
-
Publication number: 20100168712Abstract: A reconstitution device for storing a first component of a pharmaceutical preparation includes a receptacle, a cap having a first end secured to the receptacle, a second end, and an inner bore having a central aperture. The device further includes a stopper located between the receptacle and the cap, the stopper including a portion capable of being perforated. The device also includes a plunger secured to the second end of the cap, a locking mechanism located in the cap, and an actuating mechanism. The actuating mechanism may prevent the device from inadvertent activation.Type: ApplicationFiled: May 24, 2007Publication date: July 1, 2010Applicant: BAYER HEALTHCARE LLCInventors: Jonathan David Tuckwell, Robert Dyer, Robert Owen Kivlin, John Peter Palmer-Felgate, Matthew Burgess Avery, Kevin George Skinner, Chris Kadamus, Lee Wood, Peter Schwan, Ben Arlett