Patents by Inventor Jonathan David Wrigley

Jonathan David Wrigley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutants of Human App and Their Use for the Production of Transgenice Animals
    Publication number: 20100017894
    Abstract: A modified amyloid precursor protein can be expressed from a DNA construct comprising an APP DNA sequence, or a fragment or artificial substrate thereof, encoding the mutation I45W, I45Y V46W or V46Y (numbering relative to A4CT); the use of the DNA construct in the generation of cell lines or transgenic animals and the use of these proteins or such transgenic animals in the diagnosis of Alzheimer's Disease and screening putative drugs against Alzheimer's Disease are also described.
    Type: Application
    Filed: June 13, 2006
    Publication date: January 21, 2010
    Inventors: Dirk Beher, Jonathan David Wrigley
  • Treatment for Alzheimer's Disease and Related Conditions
    Publication number: 20080153817
    Abstract: Compounds of formula (I): are useful in the treatment of diseases associated with deposition of ?-amyloid in the brain.
    Type: Application
    Filed: July 29, 2004
    Publication date: June 26, 2008
    Inventors: Dirk Beher, Michela Bettati, Graham David Checksfield, Ian Churcher, Victoria Alexandra Doughty, Paul Joseph Oakley, Abdul Quddus, Martin Richard Teall, Jonathan David Wrigley